mtDNA diversity in human populations highlights the merit of haplotype matching in gene therapies

Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes

(2016) Mitsutoshi Yamada et al.   Cell Stem Cell

The role of mitochondrial DNA copy number, variants, and haplotypes in farm animal developmental outcome

(2016) Tesha Tsai et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Segregation of Naturally Occurring Mitochondrial DNA Variants in a Mini-Pig Model

(2016) G. Cagnone et al.   GENETICS

Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease

(2016) Louise A. Hyslop et al.   NATURE

Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing

(2016) Ana Latorre-Pellicer et al.   NATURE

Mitochondrial DNA copy number and replication in reprogramming and differentiation

(2016) Justin C. St. John   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Evolutionary Inference across Eukaryotes Identifies Specific Pressures Favoring Mitochondrial Gene Retention

(2016) Iain G. Johnston et al.   Cell Systems

Mitochondrial DNA Variation in Human Radiation and Disease

(2015) Douglas C. Wallace   CELL

Risks inherent to mitochondrial replacement

(2015) E. H. Morrow et al.   EMBO REPORTS

Multiple hypothesis correction is vital and undermines reported mtDNA links to diseases including AIDS, cancer, and Huntingdon’s

(2015) Iain G. Johnston   Mitochondrial DNA

Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism

(2015) Iain G Johnston et al.   eLife

Mitochondrial DNA disease and developmental implications for reproductive strategies

(2014) Joerg Patrick Burgstaller et al.   MOLECULAR HUMAN REPRODUCTION

Limitations of Preimplantation Genetic Diagnosis for Mitochondrial DNA Diseases

(2014) Shoukhrat Mitalipov et al.   Cell Reports

mtDNA Segregation in Heteroplasmic Tissues Is Common In Vivo and Modulated by Haplotype Differences and Developmental Stage

(2014) Joerg Patrick Burgstaller et al.   Cell Reports

Evolutionary perspectives on the links between mitochondrial genotype and disease phenotype

(2013) Damian K. Dowling   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mitochondrial genetics

(2013) P. F. Chinnery et al.   BRITISH MEDICAL BULLETIN

No recombination of mtDNA after heteroplasmy for 50 generations in the mouse maternal germline

(2013) E. Hagstrom et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial Replacement, Evolution, and the Clinic

(2013) K. Reinhardt et al.   SCIENCE

Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and Disease

(2013) D. C. Wallace et al.   Cold Spring Harbor Perspectives in Biology

The Maintenance of Mitochondrial DNA Integrity--Critical Analysis and Update

(2013) M. Alexeyev et al.   Cold Spring Harbor Perspectives in Biology

Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and Cognition

(2012) Mark S. Sharpley et al.   CELL

Transmission, inheritance and replication of mitochondrial DNA in mammals: implications for reproductive processes and infertility

(2012) Justin C. St John   CELL AND TISSUE RESEARCH

Blastocyst preimplantation genetic diagnosis (PGD) of a mitochondrial DNA disorder

(2012) Nathan R. Treff et al.   FERTILITY AND STERILITY

Complete Mitochondrial Genomes Reveal Neolithic Expansion into Europe

(2012) Qiaomei Fu et al.   PLoS One

Rebooting the human mitochondrial phylogeny: an automated and scalable methodology with expert knowledge

(2011) Roberto Blanco et al.   BMC BIOINFORMATICS

Segregation of mtDNA throughout human embryofetal development: m.3243A>G as a model system

(2010) Sophie Monnot et al.   HUMAN MUTATION

Mitochondrial DNA transmission, replication and inheritance: a journey from the gamete through the embryo and into offspring and embryonic stem cells

(2010) J. C. St. John et al.   HUMAN REPRODUCTION UPDATE

Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease

(2010) Lyndsey Craven et al.   NATURE

Pronounced Segregation of Donor Mitochondria Introduced by Bovine Ooplasmic Transfer to the Female Germ-Line1

(2009) Christina Ramires Ferreira et al.   BIOLOGY OF REPRODUCTION

Mitochondrial gene replacement in primate offspring and embryonic stem cells

(2009) Masahito Tachibana et al.   NATURE

Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes

(2009) A. W. Briggs et al.   SCIENCE

The Dawn of Human Matrilineal Diversity

(2008) Doron M. Behar et al.   AMERICAN JOURNAL OF HUMAN GENETICS