Unraveling the role of TGFβ signaling in thoracic aortic aneurysm and dissection using Fbn1 mutant mouse models

TGFβ-2 haploinsufficiency causes early death in mice with Marfan syndrome

(2023) Nalani Sachan et al.   MATRIX BIOLOGY

The Role of TGFβ and Other Cytokines in Regulating Mast Cell Functions in Allergic Inflammation

(2022) Tamara T. Haque et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Marfan syndrome

(2021) Dianna M. Milewicz et al.   Nature Reviews Disease Primers

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

(2021) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Fibrillin‐1 in the Vasculature: In Vivo Accumulation of eGFP‐Tagged Fibrillin‐1 in a Knockin Mouse Model

(2019) Noe L. Charbonneau et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Propagation-based phase-contrast synchrotron imaging of aortic dissection in mice: from individual elastic lamella to 3D analysis

(2018) Gerlinde Logghe et al.   Scientific Reports

Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue

(2017) Deanna L. Plubell et al.   MOLECULAR & CELLULAR PROTEOMICS

Sex, pregnancy and aortic disease in Marfan syndrome

(2017) Marjolijn Renard et al.   PLoS One

FBN1 : The disease-causing gene for Marfan syndrome and other genetic disorders

(2016) Lynn Y. Sakai et al.   GENE

Dimorphic Effects of Transforming Growth Factor-β Signaling During Aortic Aneurysm Progression in Mice Suggest a Combinatorial Therapy for Marfan SyndromeSignificance

(2015) Jason R. Cook et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Beneficial Outcome of Losartan Therapy Depends on Type ofFBN1Mutation in Marfan SyndromeCLINICAL PERSPECTIVE

(2015) Romy Franken et al.   Circulation-Cardiovascular Genetics

Marfan Sartan: a randomized, double-blind, placebo-controlled trial

(2015) Olivier Milleron et al.   EUROPEAN HEART JOURNAL

Mutations in a TGF-β Ligand, TGFB3, Cause Syndromic Aortic Aneurysms and Dissections

(2015) Aida M. Bertoli-Avella et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The fibrillin microfibril scaffold: A niche for growth factors and mechanosensation?

(2015) Gerhard Sengle et al.   MATRIX BIOLOGY

Beneficial Outcome of Losartan Therapy Depends on Type ofFBN1Mutation in Marfan SyndromeCLINICAL PERSPECTIVE

(2015) Romy Franken et al.   Circulation-Cardiovascular Genetics

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis

(2014) Wei Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Atenolol versus Losartan in Children and Young Adults with Marfan's Syndrome

(2014) Ronald V. Lacro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thoracic Aortic Aneurysm Frequency and Dissection Are Associated With Fibrillin-1 Fragment Concentrations in Circulation

(2013) Lynn M. Marshall et al.   CIRCULATION RESEARCH

Matrix-dependent perturbation of TGFβ signaling and disease

(2012) Jefferson J. Doyle et al.   FEBS LETTERS

Thoracic aortic-aneurysm and dissection in association with significant mitral valve disease caused by mutations in TGFB2

(2012) Marjolijn Renard et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Specificity of latent TGF-β binding protein (LTBP) incorporation into matrix: Role of fibrillins and fibronectin

(2012) Lior Zilberberg et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A cross-platform toolkit for mass spectrometry and proteomics

(2012) Matthew C Chambers et al.   NATURE BIOTECHNOLOGY

Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm

(2012) Mark E Lindsay et al.   NATURE GENETICS

TGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome

(2012) Catherine Boileau et al.   NATURE GENETICS

Comet: An open-source MS/MS sequence database search tool

(2012) Jimmy K. Eng et al.   PROTEOMICS

Mast Cell Tryptase Deficiency Attenuates Mouse Abdominal Aortic Aneurysm Formation

(2011) Jie Zhang et al.   CIRCULATION RESEARCH

In VivoStudies of Mutant Fibrillin-1 Microfibrils

(2010) Noe L. Charbonneau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Critical Role of Mast Cell Chymase in Mouse Abdominal Aortic Aneurysm Formation

(2009) Jiusong Sun et al.   CIRCULATION

Latent Transforming Growth Factor β-binding Proteins and Fibulins Compete for Fibrillin-1 and Exhibit Exquisite Specificities in Binding Sites

(2009) Robert N. Ono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY