Adapted risk stratification and intensive chemotherapy abrogate the poor prognosis of pediatric B acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21 (iAMP21): a National cohort analysis

The genomic landscape of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

(2023) Qingsong Gao et al.   BLOOD

Integrating copy number data of 64 iAMP21 BCP-ALL patients narrows the common region of amplification to 1.57 Mb

(2023) Femke M. Hormann et al.   Frontiers in Oncology

Characterization of unusual iAMP21 B‐lymphoblastic leukemia ( iAMP21‐ALL ) from the Mayo Clinic and Children's Oncology Group

(2022) Alaa Koleilat et al.   GENES CHROMOSOMES & CANCER

SH2B3 inactivation through CN-LOH 12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain

(2019) Paul B. Sinclair et al.   LEUKEMIA

The role of the RAS pathway in iAMP21-ALL

(2016) S L Ryan et al.   LEUKEMIA

Risk-Directed Treatment Intensification Significantly Reduces the Risk of Relapse Among Children and Adolescents With Acute Lymphoblastic Leukemia and Intrachromosomal Amplification of Chromosome 21: A Comparison of the MRC ALL97/99 and UKALL2003 Trials

(2013) Anthony V. Moorman et al.   JOURNAL OF CLINICAL ONCOLOGY

Intrachromosomal Amplification of Chromosome 21 Is Associated With Inferior Outcomes in Children With Acute Lymphoblastic Leukemia Treated in Contemporary Standard-Risk Children's Oncology Group Studies: A Report From the Children's Oncology Group

(2013) Nyla A. Heerema et al.   JOURNAL OF CLINICAL ONCOLOGY

Detection of prognostically relevant genetic abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfürt-Münster study group

(2010) Christine J. Harrison et al.   BRITISH JOURNAL OF HAEMATOLOGY

Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial

(2010) Anthony V Moorman et al.   LANCET ONCOLOGY

Minimal Residual Disease Values Discriminate Between Low and High Relapse Risk in Children With B-Cell Precursor Acute Lymphoblastic Leukemia and an Intrachromosomal Amplification of Chromosome 21: The Austrian and German Acute Lymphoblastic Leukemia Berlin-Frankfurt-Münster (ALL-BFM) Trials

(2008) Andishe Attarbaschi et al.   JOURNAL OF CLINICAL ONCOLOGY