Single-cell analysis of immune recognition in chronic myeloid leukemia patients following tyrosine kinase inhibitor discontinuation
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Single-cell analysis of immune recognition in chronic myeloid leukemia patients following tyrosine kinase inhibitor discontinuation
Authors
Keywords
-
Journal
LEUKEMIA
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-11-03
DOI
10.1038/s41375-023-02074-w
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Association of TIM-3 checkpoint receptor expression on T cells with treatment-free remission in chronic myeloid leukemia
- (2023) Yazad Darius Irani et al. Blood Advances
- Cross-tissue immune cell analysis reveals tissue-specific features in humans
- (2022) C. Domínguez Conde et al. SCIENCE
- Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia
- (2022) Jani Huuhtanen et al. Nature Communications
- Evolution and modulation of antigen-specific T cell responses in melanoma patients
- (2022) Jani Huuhtanen et al. Nature Communications
- Improving outcomes in chronic myeloid leukemia through harnessing the immunological landscape
- (2021) Ya-Ching Hsieh et al. LEUKEMIA
- Predicting recognition between T cell receptors and epitopes with TCRGP
- (2021) Emmi Jokinen et al. PLoS Computational Biology
- Integrated analysis of multimodal single-cell data
- (2021) Yuhan Hao et al. CELL
- Longitudinal single-cell dynamics of chromatin accessibility and mitochondrial mutations in chronic lymphocytic leukemia mirror disease history
- (2021) Livius Penter et al. Cancer Discovery
- Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy
- (2021) Pavan Bachireddy et al. Cell Reports
- Peripheral T cell expansion predicts tumour infiltration and clinical response
- (2020) Thomas D. Wu et al. NATURE
- CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes
- (2020) Mirjana Efremova et al. Nature Protocols
- Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL
- (2020) André F. Rendeiro et al. Nature Communications
- Successful treatment‐free remission in chronic myeloid leukaemia and its association with reduced immune suppressors and increased natural killer cells
- (2020) Yazad D. Irani et al. BRITISH JOURNAL OF HAEMATOLOGY
- Analyzing the Mycobacterium tuberculosis immune response by T-cell receptor clustering with GLIPH2 and genome-wide antigen screening
- (2020) Huang Huang et al. NATURE BIOTECHNOLOGY
- Immunogenomic Landscape of Hematological Malignancies
- (2020) Olli Dufva et al. CANCER CELL
- Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
- (2019) Dvir Aran et al. NATURE IMMUNOLOGY
- Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity
- (2019) Peter van Galen et al. CELL
- Immunological monitoring of newly diagnosed CML patients treated with bosutinib or imatinib first-line
- (2019) Anna Kreutzman et al. OncoImmunology
- Silent NK/T Cell Reactions Against Dasatinib during Sustained Deep Molecular Response before Discontinuation Are Associated with Longer Treatment-Free Remission: A Multicenter, Single-Arm, Phase 2 Study
- (2019) Takashi Kumagai et al. BLOOD
- Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome
- (2019) Chao Yang et al. Nature Communications
- The Diagnostic, Prognostic, and Therapeutic Potential of Adaptive Immune Receptor Repertoire Profiling in Cancer
- (2019) Lindsay G. Cowell CANCER RESEARCH
- Discontinuation of tyrosine kinase inhibitor therapy in chronic myeloid leukaemia (EURO-SKI): a prespecified interim analysis of a prospective, multicentre, non-randomised, trial
- (2018) Susanne Saussele et al. LANCET ONCOLOGY
- Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML
- (2018) Oscar Brück et al. LEUKEMIA
- Bias, robustness and scalability in single-cell differential expression analysis
- (2018) Charlotte Soneson et al. NATURE METHODS
- Long-term treatment-free remission of chronic myeloid leukemia with falling levels of residual leukemic cells
- (2018) David M. Ross et al. LEUKEMIA
- Dimensionality reduction for visualizing single-cell data using UMAP
- (2018) Etienne Becht et al. NATURE BIOTECHNOLOGY
- Deep generative modeling for single-cell transcriptomics
- (2018) Romain Lopez et al. NATURE METHODS
- Natural killer-cell counts are associated with molecular relapse-free survival after imatinib discontinuation in chronic myeloid leukemia: the IMMUNOSTIM study
- (2017) Delphine Rea et al. HAEMATOLOGICA
- Quantifiable predictive features define epitope-specific T cell receptor repertoires
- (2017) Pradyot Dash et al. NATURE
- Identifying specificity groups in the T cell receptor repertoire
- (2017) Jacob Glanville et al. NATURE
- Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire
- (2017) Ryan O Emerson et al. NATURE GENETICS
- Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia
- (2017) Alice Giustacchini et al. NATURE MEDICINE
- Natural killer-cell counts are associated with molecular relapse-free survival after imatinib discontinuation in chronic myeloid leukemia: the IMMUNOSTIM study
- (2017) Delphine Rea et al. HAEMATOLOGICA
- Immune Effector Recovery in Chronic Myeloid Leukemia and Treatment-Free Remission
- (2017) Amy Hughes et al. Frontiers in Immunology
- Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia
- (2016) M Ilander et al. LEUKEMIA
- Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
- (2016) I. Tirosh et al. SCIENCE
- Age and dPCR can predict relapse in CML patients who discontinued imatinib: The ISAV study
- (2015) Silvia Mori et al. AMERICAN JOURNAL OF HEMATOLOGY
- VDJtools: Unifying Post-analysis of T Cell Receptor Repertoires
- (2015) Mikhail Shugay et al. PLoS Computational Biology
- Discontinuation of dasatinib in patients with chronic myeloid leukaemia who have maintained deep molecular response for longer than 1 year (DADI trial): a multicentre phase 2 trial
- (2015) Jun Imagawa et al. Lancet Haematology
- Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study
- (2013) D. M. Ross et al. BLOOD
- Using synthetic templates to design an unbiased multiplex PCR assay
- (2013) Christopher S. Carlson et al. Nature Communications
- Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9
- (2012) M. K. Gleason et al. BLOOD
- Rapid mobilization of cytotoxic lymphocytes induced by dasatinib therapy
- (2012) S Mustjoki et al. LEUKEMIA
- clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
- (2012) Guangchuang Yu et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Membrane-Bound IL-21 Promotes Sustained Ex Vivo Proliferation of Human Natural Killer Cells
- (2012) Cecele J. Denman et al. PLoS One
- Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival
- (2011) A. Hamilton et al. BLOOD
- Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity
- (2010) Amie S. Corbin et al. JOURNAL OF CLINICAL INVESTIGATION
- Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial
- (2010) François-Xavier Mahon et al. LANCET ONCOLOGY
- Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy
- (2009) S Mustjoki et al. LEUKEMIA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More