The role of the dynein light intermediate chain in retrograde IFT and flagellar function in Chlamydomonas

Single-particle imaging reveals intraflagellar transport–independent transport and accumulation of EB1 in Chlamydomonas flagella

(2016) J. Aaron Harris et al.   MOLECULAR BIOLOGY OF THE CELL

Novel compound heterozygous mutations inDYNC2H1in a patient with severe short-rib polydactyly syndrome type III phenotype

(2015) Toshio Okamoto et al.   CONGENITAL ANOMALIES

Proteomic Analysis of Isolated Ciliary Transition Zones Reveals the Presence of ESCRT Proteins

(2015) Dennis R. Diener et al.   CURRENT BIOLOGY

Dynein and intraflagellar transport

(2015) Yuqing Hou et al.   EXPERIMENTAL CELL RESEARCH

Physiological and pathological views of peroxiredoxin 4

(2015) Junichi Fujii et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tubulin transport by IFT is upregulated during ciliary growth by a cilium-autonomous mechanism

(2015) Julie M. Craft et al.   JOURNAL OF CELL BIOLOGY

Global genetic analysis in mice unveils central role for cilia in congenital heart disease

(2015) You Li et al.   NATURE

IFT–Cargo Interactions and Protein Transport in Cilia

(2015) Karl F. Lechtreck   TRENDS IN BIOCHEMICAL SCIENCES

Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome

(2015) S. Paige Taylor et al.   Nature Communications

TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport

(2015) Miriam Schmidts et al.   Nature Communications

DYNC2LI1 mutations broaden the clinical spectrum of dynein-2 defects

(2015) Kristin Kessler et al.   Scientific Reports

Novel compound heterozygous mutations inDYNC2H1in a patient with severe short-rib polydactyly syndrome type III phenotype

(2015) Toshio Okamoto et al.   CONGENITAL ANOMALIES

Function and regulation of primary cilia and intraflagellar transport proteins in the skeleton

(2014) Xue Yuan et al.   Annals of the New York Academy of Sciences

Peroxiredoxin 1 is involved in disassembly of flagella and cilia

(2014) Fanghua Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tuning of Peroxiredoxin Catalysis for Various Physiological Roles

(2014) Arden Perkins et al.   BIOCHEMISTRY

Cilia and Diseases

(2014) Jason M. Brown et al.   BIOSCIENCE

FLA8/KIF3B Phosphorylation Regulates Kinesin-II Interaction with IFT-B to Control IFT Entry and Turnaround

(2014) Yinwen Liang et al.   DEVELOPMENTAL CELL

Primary cilium: an elaborate structure that blocks cell division?

(2014) Yi-Ni Ke et al.   GENE

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm

(2014) Fenglan Dong et al.   JOURNAL OF CELL BIOLOGY

NPHP4 controls ciliary trafficking of membrane proteins and large soluble proteins at the transition zone

(2014) J. Awata et al.   JOURNAL OF CELL SCIENCE

Hsp90  forms a stable complex at the cilium neck for the interaction of signalling molecules in IGF-1 receptor signalling

(2014) H. Wang et al.   JOURNAL OF CELL SCIENCE

Subunit composition of the human cytoplasmic dynein-2 complex

(2014) D. Asante et al.   JOURNAL OF CELL SCIENCE

The intraflagellar transport dynein complex of trypanosomes is made of a heterodimer of dynein heavy chains and of light and intermediate chains of distinct functions

(2014) Thierry Blisnick et al.   MOLECULAR BIOLOGY OF THE CELL

Primary cilium-associated genes mediate bone marrow stromal cell response to hypoxia

(2014) James A.L. Brown et al.   Stem Cell Research

WDR34 Mutations that Cause Short-Rib Polydactyly Syndrome Type III/Severe Asphyxiating Thoracic Dysplasia Reveal a Role for the NF-κB Pathway in Cilia

(2013) Céline Huber et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Short-Rib Polydactyly and Jeune Syndromes Are Caused by Mutations in WDR60

(2013) Aideen M. McInerney-Leo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in the Gene Encoding IFT Dynein Complex Component WDR34 Cause Jeune Asphyxiating Thoracic Dystrophy

(2013) Miriam Schmidts et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fetal iron deficiency alters the proteome of adult rat hippocampal synaptosomes

(2013) Phu V. Tran et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Kinesin-2: A Family of Heterotrimeric and Homodimeric Motors with Diverse Intracellular Transport Functions

(2013) Jonathan M. Scholey   Annual Review of Cell and Developmental Biology

Expanding Horizons: Ciliary Proteins Reach Beyond Cilia

(2013) Shiaulou Yuan et al.   Annual Review of Genetics

A Differential Cargo-Loading Model of Ciliary Length Regulation by IFT

(2013) Kathryne N. Wren et al.   CURRENT BIOLOGY

Compartmentalized Calcium Signaling in Cilia Regulates Intraflagellar Transport

(2013) Peter Collingridge et al.   CURRENT BIOLOGY

Cycling of the signaling protein phospholipase D through cilia requires the BBSome only for the export phase

(2013) Karl F. Lechtreck et al.   JOURNAL OF CELL BIOLOGY

Centrosomal protein CEP104 (Chlamydomonas FAP256) moves to the ciliary tip during ciliary assembly

(2013) T. V. Satish Tammana et al.   JOURNAL OF CELL SCIENCE

Exome sequencing identifiesDYNC2H1mutations as a common cause of asphyxiating thoracic dystrophy (Jeune syndrome) without major polydactyly, renal or retinal involvement

(2013) Miriam Schmidts et al.   JOURNAL OF MEDICAL GENETICS

WD60/FAP163 is a dynein intermediate chain required for retrograde intraflagellar transport in cilia

(2013) Ramila S. Patel-King et al.   MOLECULAR BIOLOGY OF THE CELL

The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes

(2013) Raqual Bower et al.   MOLECULAR BIOLOGY OF THE CELL

Proteomic Analysis of Bovine Axonemes Exposed to Acute Alcohol: Role of Endothelial Nitric Oxide Synthase and Heat Shock Protein 90 in Cilia Stimulation

(2012) Samantha M. Simet et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Proteomic Analysis of Mammalian Primary Cilia

(2012) Hiroaki Ishikawa et al.   CURRENT BIOLOGY

High-pH reversed-phase chromatography with fraction concatenation for 2D proteomic analysis

(2012) Feng Yang et al.   Expert Review of Proteomics

Re-evaluation of the Role of Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) in Cellular Calcium Signaling

(2012) Yaping Lin-Moshier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of retrograde intraflagellar transport in flagellar assembly, maintenance, and function

(2012) Benjamin D. Engel et al.   JOURNAL OF CELL BIOLOGY

Heat shock induces rapid resorption of primary cilia

(2012) N. V. Prodromou et al.   JOURNAL OF CELL SCIENCE

Intraflagellar transport proteins cycle between the flagellum and its base

(2012) Johanna Buisson et al.   JOURNAL OF CELL SCIENCE

A cell-based screen for inhibitors of flagella-driven motility in Chlamydomonas reveals a novel modulator of ciliary length and retrograde actin flow

(2011) Benjamin D. Engel et al.   Cytoskeleton

A role for Tctex-1 (DYNLT1) in controlling primary cilium length

(2011) Krysten J. Palmer et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

bop5 mutations reveal new roles for the IC138 phosphoprotein in the regulation of flagellar motility and asymmetric waveforms

(2011) Kristyn E. VanderWaal et al.   MOLECULAR BIOLOGY OF THE CELL

Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors

(2011) Aiqun Li et al.   NATURE CELL BIOLOGY

Ciliogenesis: building the cell's antenna

(2011) Hiroaki Ishikawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Retrograde IFT Machinery of C. elegans Cilia: Two IFT Dynein Complexes?

(2011) Limin Hao et al.   PLoS One

Reduction-oxidation poise regulates the sign of phototaxis in Chlamydomonas reinhardtii

(2011) K.-i. Wakabayashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen Peroxide Modifies Human Sperm Peroxiredoxins in a Dose-Dependent Manner

(2010) C. O'Flaherty et al.   BIOLOGY OF REPRODUCTION

The 90-kDa Heat Shock Protein Hsp90 Protects Tubulin against Thermal Denaturation

(2010) Felix Weis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discrete PIH proteins function in the cytoplasmic preassembly of different subsets of axonemal dyneins

(2010) Ryosuke Yamamoto et al.   JOURNAL OF CELL BIOLOGY

Ciliary Abnormalities Due to Defects in the Retrograde Transport Protein DYNC2H1 in Short-Rib Polydactyly Syndrome

(2009) Amy E. Merrill et al.   AMERICAN JOURNAL OF HUMAN GENETICS

DYNC2H1 Mutations Cause Asphyxiating Thoracic Dystrophy and Short Rib-Polydactyly Syndrome, Type III

(2009) Nathalie Dagoneau et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Novel LC8 Mutations Have Disparate Effects on the Assembly and Stability of Flagellar Complexes

(2009) Pinfen Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HA-tagging of putative flagellar proteins inChlamydomonas reinhardtiiidentifies a novel protein of intraflagellar transport complex B

(2009) Karl-Ferdinand Lechtreck et al.   CELL MOTILITY AND THE CYTOSKELETON

Intraflagellar transport, cilia, and mammalian Hedgehog signaling: Analysis in mouse embryonic fibroblasts

(2008) Polloneal Jymmiel R. Ocbina et al.   DEVELOPMENTAL DYNAMICS

The Peroxiredoxin and Glutathione Peroxidase Families in Chlamydomonas reinhardtii

(2008) R. Dayer et al.   GENETICS

ODA16 aids axonemal outer row dynein assembly through an interaction with the intraflagellar transport machinery

(2008) Noveera T. Ahmed et al.   JOURNAL OF CELL BIOLOGY

Dynein-2 Affects the Regulation of Ciliary Length but Is Not Required for Ciliogenesis in Tetrahymena thermophila

(2008) Vidyalakshmi Rajagopalan et al.   MOLECULAR BIOLOGY OF THE CELL