Coevolution of URAT1 and Uricase during Primate Evolution: Implications for Serum Urate Homeostasis and Gout

Tree of Life Reveals Clock-Like Speciation and Diversification

(2015) S. Blair Hedges et al.   MOLECULAR BIOLOGY AND EVOLUTION

Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids

(2014) Christina Cicerchi et al.   FASEB JOURNAL

Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes

(2014) Yea-Jin Choi et al.   LABORATORY INVESTIGATION

Evolutionary history and metabolic insights of ancient mammalian uricases

(2014) J. T. Kratzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comorbidities in Patients with Crystal Diseases and Hyperuricemia

(2014) Sebastian E. Sattui et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Comorbidities of Gout and Hyperuricemia in the US General Population: NHANES 2007-2008

(2012) Yanyan Zhu et al.   AMERICAN JOURNAL OF MEDICINE

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

(2012) Anna Köttgen et al.   NATURE GENETICS

Identification and functional characterization of uric acid transporter Urat1 (Slc22a12) in rats

(2010) Masanobu Sato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Large-Scale Analysis of Orthologs and Paralogs under Covarion-Like and Constant-but-Different Models of Amino Acid Evolution

(2010) R. A. Studer et al.   MOLECULAR BIOLOGY AND EVOLUTION

Plasma Urate Level Is Directly Regulated by a Voltage-driven Urate Efflux Transporter URATv1 (SLC2A9) in Humans

(2008) Naohiko Anzai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palaeotemperature trend for Precambrian life inferred from resurrected proteins

(2008) Eric A. Gaucher et al.   NATURE