Pervasive Effects of Aging on Gene Expression in Wild Wolves

Chromatin modifications: The driving force of senescence and aging?

(2016) Teresa DiMauro et al.   Aging-US

Ancient Wolf Genome Reveals an Early Divergence of Domestic Dog Ancestors and Admixture into High-Latitude Breeds

(2015) Pontus Skoglund et al.   CURRENT BIOLOGY

Social living mitigates the costs of a chronic illness in a cooperative carnivore

(2015) E. S. Almberg et al.   ECOLOGY LETTERS

Worldwide patterns of genomic variation and admixture in gray wolves

(2015) Zhenxin Fan et al.   GENOME RESEARCH

Human-specific derived alleles ofCD33and other genes protect against postreproductive cognitive decline

(2015) Flavio Schwarz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The transcriptional landscape of age in human peripheral blood

(2015) Marjolein J. Peters et al.   Nature Communications

The genetic architecture of gene expression levels in wild baboons

(2015) Jenny Tung et al.   eLife

Environmental and Intrinsic Correlates of Stress in Free-Ranging Wolves

(2015) Barbara Molnar et al.   PLoS One

Shared signatures of social stress and aging in peripheral blood mononuclear cell gene expression profiles

(2014) Noah Snyder-Mackler et al.   AGING CELL

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Density-dependent intraspecific aggression regulates survival in northern Yellowstone wolves (Canis lupus)

(2014) Sarah Cubaynes et al.   JOURNAL OF ANIMAL ECOLOGY

The application of transcriptional blood signatures to enhance our understanding of the host response to infection: the example of tuberculosis

(2014) S. Blankley et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

An Improved Canine Genome and a Comprehensive Catalogue of Coding Genes and Non-Coding Transcripts

(2014) Marc P. Hoeppner et al.   PLoS One

Age-Related Declines and Disease-Associated Variation in Immune Cell Telomere Length in a Wild Mammal

(2014) Christopher Beirne et al.   PLoS One

Genome Sequencing Highlights the Dynamic Early History of Dogs

(2014) Adam H. Freedman et al.   PLoS Genetics

The Size–Life Span Trade-Off Decomposed: Why Large Dogs Die Young

(2013) Cornelia Kraus et al.   AMERICAN NATURALIST

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Review of Ets1 structure, function, and roles in immunity

(2013) Lee Ann Garrett-Sinha   CELLULAR AND MOLECULAR LIFE SCIENCES

Transcriptional profiling in infectious diseases: Ready for prime time?

(2013) Asuncion Mejias et al.   JOURNAL OF INFECTION

Systematic evaluation of spliced alignment programs for RNA-seq data

(2013) Pär G Engström et al.   NATURE METHODS

Social environment influences the relationship between genotype and gene expression in wild baboons

(2013) D. E. Runcie et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via  -adrenergic induction of myelopoiesis

(2013) N. D. Powell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complete Mitochondrial Genomes of Ancient Canids Suggest a European Origin of Domestic Dogs

(2013) O. Thalmann et al.   SCIENCE

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Senescence in natural populations of animals: Widespread evidence and its implications for bio-gerontology

(2012) Daniel H. Nussey et al.   AGEING RESEARCH REVIEWS

Removing technical variability in RNA-seq data using conditional quantile normalization

(2012) K. D. Hansen et al.   BIOSTATISTICS

The adaptive value of morphological, behavioural and life-history traits in reproductive female wolves

(2012) Daniel R. Stahler et al.   JOURNAL OF ANIMAL ECOLOGY

The insulin-like growth factor 1 receptor (IGF1R) contributes to reduced size in dogs

(2012) Barbara C. Hoopes et al.   MAMMALIAN GENOME

Genome-wide efficient mixed-model analysis for association studies

(2012) Xiang Zhou et al.   NATURE GENETICS

Parasite invasion following host reintroduction: a case study of Yellowstone's wolves

(2012) E. S. Almberg et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Social environment is associated with gene regulatory variation in the rhesus macaque immune system

(2012) J. Tung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional modulation of the developing immune system by early life social adversity

(2012) S. W. Cole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phylogenomic datasets provide both precision and accuracy in estimating the timescale of placental mammal phylogeny

(2012) M. dos Reis et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Quorum-Sensing in CD4+ T Cell Homeostasis: A Hypothesis and a Model

(2012) Afonso R. M. Almeida et al.   Frontiers in Immunology

Regulatory T Cells and Parasites

(2011) TP. Velavan et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform

(2011) Martin Kircher et al.   NUCLEIC ACIDS RESEARCH

Transcript origin analysis identifies antigen-presenting cells as primary targets of socially regulated gene expression in leukocytes

(2011) S. W. Cole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Consequences of immune system aging in nature: a study of immunosenescence costs in free-living Tree Swallows

(2010) Maria G. Palacios et al.   ECOLOGY

A novel assessment of population structure and gene flow in grey wolf populations of the Northern Rocky Mountains of the United States

(2010) BRIDGETT M. VONHOLDT et al.   MOLECULAR ECOLOGY

coancestry: a program for simulating, estimating and analysing relatedness and inbreeding coefficients

(2010) JINLIANG WANG   Molecular Ecology Resources

Maternal warmth buffers the effects of low early-life socioeconomic status on pro-inflammatory signaling in adulthood

(2010) E Chen et al.   MOLECULAR PSYCHIATRY

Life-history connections to rates of aging in terrestrial vertebrates

(2010) R. E. Ricklefs   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression ofp16INK4ain peripheral blood T-cells is a biomarker of human aging

(2009) Yan Liu et al.   AGING CELL

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Insulin/IGF-1 paradox of aging: Regulation via AKT/IKK/NF-κB signaling

(2009) Antero Salminen et al.   CELLULAR SIGNALLING

Predatory senescence in ageing wolves

(2009) Daniel R. MacNulty et al.   ECOLOGY LETTERS

Body size and predatory performance in wolves: is bigger better?

(2009) Daniel R. MacNulty et al.   JOURNAL OF ANIMAL ECOLOGY

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

(2009) Patrick O McGowan et al.   NATURE NEUROSCIENCE

A Serological Survey of Infectious Disease in Yellowstone National Park’s Canid Community

(2009) Emily S. Almberg et al.   PLoS One

Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling

(2009) G. E. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FCI: an R-based algorithm for evaluating uncertainty of absolute real-time PCR quantification

(2008) Paolo Verderio et al.   BMC BIOINFORMATICS

Transcriptome-Wide Assessment of Human Brain and Lymphocyte Senescence

(2008) Mun-Gwan Hong et al.   PLoS One

The genealogy and genetic viability of reintroduced Yellowstone grey wolves

(2007) BRIDGETT M. VONHOLDT et al.   MOLECULAR ECOLOGY