Adaptive Genetic Robustness ofEscherichia coliMetabolic Fluxes

Pervasive robustness in biological systems

(2015) Marie-Anne Félix et al.   NATURE REVIEWS GENETICS

The Genotype–Phenotype Map of Yeast Complex Traits: Basic Parameters and the Role of Natural Selection

(2014) Wei-Chin Ho et al.   MOLECULAR BIOLOGY AND EVOLUTION

Constraint-based models predict metabolic and associated cellular functions

(2014) Aarash Bordbar et al.   NATURE REVIEWS GENETICS

Determinative Developmental Cell Lineages Are Robust to Cell Deaths

(2014) Jian-Rong Yang et al.   PLoS Genetics

A latent capacity for evolutionary innovation through exaptation in metabolic systems

(2013) Aditya Barve et al.   NATURE

The Ability of Flux Balance Analysis to Predict Evolution of Central Metabolism Scales with the Initial Distance to the Optimum

(2013) William R. Harcombe et al.   PLoS Computational Biology

THE EVOLUTION OF GENES IN BRANCHED METABOLIC PATHWAYS

(2012) Mark D. Rausher   EVOLUTION

Multiple capacitors for natural genetic variation inDrosophila melanogaster

(2012) Kazuo H. Takahashi   MOLECULAR ECOLOGY

Superessential reactions in metabolic networks

(2012) A. Barve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive quantitative analysis of central carbon and amino-acid metabolism in Saccharomyces cerevisiae under multiple conditions by targeted proteomics

(2011) R. Costenoble et al.   Molecular Systems Biology

Impact of gene expression noise on organismal fitness and the efficacy of natural selection

(2011) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructions

(2010) Jan Schellenberger et al.   BMC BIOINFORMATICS

Genotype networks in metabolic reaction spaces

(2010) Areejit Samal et al.   BMC Systems Biology

Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models

(2010) Nathan E Lewis et al.   Molecular Systems Biology

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks

(2010) Xionglei He et al.   NATURE GENETICS

Abundant Indispensable Redundancies in Cellular Metabolic Networks

(2009) Zhi Wang et al.   Genome Biology and Evolution

Evolutionary Plasticity and Innovations in Complex Metabolic Reaction Networks

(2009) João F. Matias Rodrigues et al.   PLoS Computational Biology

Why Is the Correlation between Gene Importance and Gene Evolutionary Rate So Weak?

(2009) Zhi Wang et al.   PLoS Genetics

Network Hubs Buffer Environmental Variation in Saccharomyces cerevisiae

(2008) Sasha F Levy et al.   PLOS BIOLOGY