Structural characterization and in silico toxicity prediction of degradation impurities of roxadustat

Characterization of stress degradation products of nintedanib by UPLC, UHPLC-Q-TOF/MS/MS and NMR: Evidence of a degradation product with a structure alert for mutagenicity

(2021) Vivek Dhiman et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A Scalable Synthesis of Roxadustat (FG-4592)

(2021) Ondřej Píša et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

LC-MS/MS studies for identification and characterization of new forced degradation products of dabrafenib and establishment of their degradation pathway

(2021) Parul Grover et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

UPLC–MS-Based Procedures to Detect Prolyl-hydroxylase Inhibitors of HIF in Urine

(2020) Monica Mazzarino et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Direct Synthesis of Chiral NH Lactams via Ru-Catalyzed Asymmetric Reductive Amination/Cyclization Cascade of Keto Acids/Esters

(2020) Yongjie Shi et al.   ORGANIC LETTERS

Roxadustat: First Global Approval

(2019) Sohita Dhillon   DRUGS

Evaluation of the effect of lanthanum carbonate hydrate on the pharmacokinetics of roxadustat in non-elderly healthy adult male subjects

(2018) T. Shibata et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Investigation of the metabolites of the HIF stabilizer FG-4592 (roxadustat) in five different in vitro models and in a human doping control sample using high resolution mass spectrometry

(2017) Annelie Hansson et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Homology modelling and molecular docking studies of human placental cadherin protein for its role in teratogenic effects of anti-epileptic drugs

(2016) Sakshi Piplani et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Forced degradation study of racecadotril: Effect of co-solvent, characterization of degradation products by UHPLC-Q-TOF-MS/MS, NMR and cytotoxicity assay

(2016) Vishnuvardhan Chiguru et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Detection by LC–MS/MS of HIF stabilizer FG-4592 used as a new doping agent: Investigation on a positive case

(2016) C. Buisson et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

CADRE-SS, an in Silico Tool for Predicting Skin Sensitization Potential Based on Modeling of Molecular Interactions

(2015) Jakub Kostal et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Chlorine-Radical-Mediated Photocatalytic Activation of CH Bonds with Visible Light

(2012) Rusheng Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in the chemistry of imine-based multicomponent reactions (MCRs)

(2011) Lokman H. Choudhury et al.   TETRAHEDRON