High-fructose diet is as detrimental as high-fat diet in the induction of insulin resistance and diabetes mediated by hepatic/pancreatic endoplasmic reticulum (ER) stress

High-fructose diet in pregnancy leads to fetal programming of hypertension, insulin resistance, and obesity in adult offspring

(2016) Antonio F. Saad et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Time Course of Molecular and Metabolic Events in the Development of Insulin Resistance in Fructose-Fed Rats

(2016) Sergio Polakof et al.   JOURNAL OF PROTEOME RESEARCH

Fructose overfeeding in first-degree relatives of type 2 diabetic patients impacts energy metabolism and mitochondrial functions in skeletal muscle

(2016) Kevin Seyssel et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Alpha lipoic acid attenuates high-fructose-induced pancreatic toxicity

(2016) Senay Topsakal et al.   PANCREATOLOGY

The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis

(2016) Mark A. Herman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Strength Training Prevents Hyperinsulinemia, Insulin Resistance, and Inflammation Independent of Weight Loss in Fructose-Fed Animals

(2016) José D. Botezelli et al.   Scientific Reports

Progressive Induction of Type 2 Diabetes: Effects of a Reality–Like Fructose Enriched Diet in Young Wistar Rats

(2016) Julie Dupas et al.   PLoS One

Fructose, but not glucose, impairs insulin signaling in the three major insulin-sensitive tissues

(2016) Miguel Baena et al.   Scientific Reports

IRE1 impairs insulin signaling transduction of fructose-fed mice via JNK independent of excess lipid

(2015) Ruo-Qiong Sun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

An Islet-Targeted Genome-Wide Association Scan Identifies Novel Genes Implicated in Cytokine-Mediated Islet Stress in Type 2 Diabetes

(2015) Poonam R. Sharma et al.   ENDOCRINOLOGY

Altered immunometabolism at the interface of increased endoplasmic reticulum (ER) stress in patients with type 2 diabetes

(2015) R. Lenin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Fructose and Cardiometabolic Health

(2015) Vasanti S. Malik et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice

(2015) Todd R. Harris et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Health Implications of High-Fructose Intake and Current Research

(2015) Waleska C Dornas et al.   Advances in Nutrition

Pdx1 Maintains β Cell Identity and Function by Repressing an α Cell Program

(2014) Tao Gao et al.   Cell Metabolism

Fructose supplementation worsens the deleterious effects of short-term high-fat feeding on hepatic steatosis and lipid metabolism in adult rats

(2014) Raffaella Crescenzo et al.   EXPERIMENTAL PHYSIOLOGY

Involvement of Increased Endogenous Asymmetric Dimethylarginine in the Hepatic Endoplasmic Reticulum Stress of Type 2 Diabetic Rats

(2014) Yi-Ping Leng et al.   PLoS One

Sugar Intake, Obesity, and Diabetes in India

(2014) Seema Gulati et al.   Nutrients

In Vivo JNK Activation in Pancreatic  -Cells Leads to Glucose Intolerance Caused by Insulin Resistance in Pancreas

(2013) J. Lanuza-Masdeu et al.   DIABETES

Effects of Common Genetic Variants Associated With Type 2 Diabetes and Glycemic Traits on α- and β-Cell Function and Insulin Action in Humans

(2013) Anna Jonsson et al.   DIABETES

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

(2013) N. Turner et al.   DIABETOLOGIA

Effects of energy-dense nutrient-poor snacks on the incidence of metabolic syndrome: A prospective approach in Tehran Lipid and Glucose Study

(2013) Parvin Mirmiran et al.   NUTRITION

Regulation of glucose metabolism via hepatic forkhead transcription factor 1 (FoxO1) by Morinda citrifolia (noni) in high-fat diet-induced obese mice

(2011) Pratibha V. Nerurkar et al.   BRITISH JOURNAL OF NUTRITION

Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes

(2011) M. Balasubramanyam et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice

(2010) Atsuyuki Tsutsumi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

(2010) Sarah Hummasti et al.   CIRCULATION RESEARCH

Endoplasmic reticulum stress in liver disease

(2010) Harmeet Malhi et al.   JOURNAL OF HEPATOLOGY

Insulin Resistance,  -Cell Dysfunction, and Conversion to Type 2 Diabetes in a Multiethnic Population: The Insulin Resistance Atherosclerosis Study

(2009) C. Lorenzo et al.   DIABETES CARE

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

(2009) Mira M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Food Intake Patterns Associated With Incident Type 2 Diabetes: The Insulin Resistance Atherosclerosis Study

(2008) A. D. Liese et al.   DIABETES CARE

Islet adaptive changes to fructose-induced insulin resistance: β-cell mass, glucokinase, glucose metabolism, and insulin secretion

(2008) B Maiztegui et al.   JOURNAL OF ENDOCRINOLOGY