Inhibition of cell survival and proliferation by nimbolide in human androgen-independent prostate cancer (PC-3) cells: involvement of the PI3K/Akt pathway

Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model

(2016) Jingwen Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Nimbolide, a neem limonoid inhibits Phosphatidyl Inositol-3 Kinase to activate Glycogen Synthase Kinase-3β in a hamster model of oral oncogenesis

(2016) Josephraj Sophia et al.   Scientific Reports

Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition

(2016) Ramadevi Subramani et al.   Scientific Reports

Nimbolide Induces ROS-Regulated Apoptosis and Inhibits Cell Migration in Osteosarcoma

(2015) Ju-Fang Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Induction of cell cycle arrest, DNA damage, and apoptosis by nimbolide in human renal cell carcinoma cells

(2015) Yi-Hsien Hsieh et al.   TUMOR BIOLOGY

c-myc Regulates Cell Proliferation during Lens Development

(2014) Gabriel R. Cavalheiro et al.   PLoS One

Inhibition of c-Myc Overcomes Cytotoxic Drug Resistance in Acute Myeloid Leukemia Cells by Promoting Differentiation

(2014) Xiao-Na Pan et al.   PLoS One

Chemopreventive and therapeutic effects of nimbolide in cancer: The underlying mechanisms

(2014) Lakshmi Narendra Bodduluru et al.   TOXICOLOGY IN VITRO

Anti-proliferative and apoptosis inducing effect of nimbolide by altering molecules involved in apoptosis and IGF signalling via PI3K/Akt in prostate cancer (PC-3) cell line

(2013) Paulraj Raja Singh et al.   CELL BIOCHEMISTRY AND FUNCTION

Direct Inhibition of Retinoblastoma Phosphorylation by Nimbolide Causes Cell-Cycle Arrest and Suppresses Glioblastoma Growth

(2013) S. Karkare et al.   CLINICAL CANCER RESEARCH

Targeting multidrug resistant Mycobacterium tuberculosis htra2 with identical chemical entities of fluoroquinolones

(2013) P Daisy et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Targeting survivin in cancer

(2012) Dario C. Altieri   CANCER LETTERS

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Induction of apoptosis in human breast cancer cells by nimbolide through extrinsic and intrinsic pathway

(2012) P. Elumalai et al.   TOXICOLOGY LETTERS

Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth

(2011) David J. Mulholland et al.   CANCER CELL

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells

(2010) R. Vidya Priyadarsini et al.   FREE RADICAL RESEARCH

Modification of Cysteine 179 of IκBα Kinase by Nimbolide Leads to Down-regulation of NF-κB-regulated Cell Survival and Proliferative Proteins and Sensitization of Tumor Cells to Chemotherapeutic Agents

(2010) Subash C. Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The neem limonoids azadirachtin and nimbolide inhibit hamster cheek pouch carcinogenesis by modulating xenobiotic-metabolizing enzymes, DNA damage, antioxidants, invasion and angiogenesis

(2009) Ramamurthi Vidya Priyadarsini et al.   FREE RADICAL RESEARCH

The TGF-β, PI3K/Akt and PTEN pathways: established and proposed biochemical integration in prostate cancer

(2008) Stephen J. Assinder et al.   BIOCHEMICAL JOURNAL

Small-Molecule Inhibitors of PDK1

(2008) Christian Peifer et al.   ChemMedChem

Nimbolide a limonoid from Azadirachta indica inhibits proliferation and induces apoptosis of human choriocarcinoma (BeWo) cells

(2008) G. Harish Kumar et al.   INVESTIGATIONAL NEW DRUGS

Quercetin promotes degradation of survivin and thereby enhances death-receptor–mediated apoptosis in glioma cells

(2008) Markus D. Siegelin et al.   NEURO-ONCOLOGY