The ratio of M1 to M2 microglia in the striatum determines the severity of L‐Dopa‐induced dyskinesias

Prevention of L-Dopa-Induced Dyskinesias by MPEP Blockade of Metabotropic Glutamate Receptor 5 Is Associated with Reduced Inflammation in the Brain of Parkinsonian Monkeys

(2022) Marc Morissette et al.   Cells

Systemic Inflammation Increases the Susceptibility to Levodopa-Induced Dyskinesia in 6-OHDA Lesioned Rats by Targeting the NR2B-Medicated PKC/MEK/ERK Pathway

(2021) Aijuan Yan et al.   Frontiers in Aging Neuroscience

Overview of General and Discriminating Markers of Differential Microglia Phenotypes

(2020) Agnieszka M. Jurga et al.   Frontiers in Cellular Neuroscience

Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation

(2019) Marta Joana Costa Jordão et al.   SCIENCE

Time dependent degeneration of the nigrostriatal tract in mice with 6-OHDA lesioned medial forebrain bundle and the effect of activin A on l-Dopa induced dyskinesia

(2019) Peggy Rentsch et al.   BMC NEUROSCIENCE

Immunomodulatory drugs alleviate l ‐dopa‐induced dyskinesia in a rat model of Parkinson's disease

(2019) Laura Boi et al.   MOVEMENT DISORDERS

Microglial subtypes: diversity within the microglial community

(2019) Vassilis Stratoulias et al.   EMBO JOURNAL

Targeting the cannabinoid receptor CB2 in a mouse model of l-dopa induced dyskinesia

(2019) Peggy Rentsch et al.   NEUROBIOLOGY OF DISEASE

Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program

(2019) Laufey Geirsdottir et al.   CELL

Levodopa-induced dyskinesia: clinical features, incidence, and risk factors

(2018) Tai N. Tran et al.   JOURNAL OF NEURAL TRANSMISSION

Minocycline promotes post-hemorrhagic neurogenesis via M2 microglia polarization via up-regulation of the TrkB/BDNF pathway in rats

(2018) Miao Hongsheng et al.   JOURNAL OF NEUROPHYSIOLOGY

Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease

(2018) Géraldine Gelders et al.   Journal of Immunology Research

Microglia and the Brain: Complementary Partners in Development and Disease

(2018) Timothy R. Hammond et al.   Annual Review of Cell and Developmental Biology

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

Activin A Inhibits MPTP and LPS-Induced Increases in Inflammatory Cell Populations and Loss of Dopamine Neurons in the Mouse Midbrain In Vivo

(2017) Sandy Stayte et al.   PLoS One

Microglia Polarization with M1/M2 Phenotype Changes in rd1 Mouse Model of Retinal Degeneration

(2017) Tian Zhou et al.   Frontiers in Neuroanatomy

Minocycline modulates microglia polarization in ischemia-reperfusion model of retinal degeneration and induces neuroprotection

(2017) Amel Ahmed et al.   Scientific Reports

Differential induction of dyskinesia and neuroinflammation by pulsatile versus continuous l -DOPA delivery in the 6-OHDA model of Parkinson's disease

(2016) Giovanna Mulas et al.   EXPERIMENTAL NEUROLOGY

Co-administration of cannabidiol and capsazepine reduces L-DOPA-induced dyskinesia in mice: Possible mechanism of action

(2016) Maurício dos-Santos-Pereira et al.   NEUROBIOLOGY OF DISEASE

Validation of an improved scale for rating l-DOPA-induced dyskinesia in the mouse and effects of specific dopamine receptor antagonists

(2016) Irene Sebastianutto et al.   NEUROBIOLOGY OF DISEASE

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Glial activation is associated with l-DOPA induced dyskinesia and blocked by a nitric oxide synthase inhibitor in a rat model of Parkinson's disease

(2015) Mariza Bortolanza et al.   NEUROBIOLOGY OF DISEASE

Activin A Protects Midbrain Neurons in the 6-Hydroxydopamine Mouse Model of Parkinson’s Disease

(2015) Sandy Stayte et al.   PLoS One

Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis

(2014) Ashley E. Frakes et al.   NEURON

Aberrant Restoration of Spines and their Synapses in L-DOPA-Induced Dyskinesia: Involvement of Corticostriatal but Not Thalamostriatal Synapses

(2013) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Microglia: A new frontier for synaptic plasticity, learning and memory, and neurodegenerative disease research

(2013) Gary P. Morris et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Minocycline selectively inhibits M1 polarization of microglia

(2013) K Kobayashi et al.   Cell Death & Disease

Development of a Unilaterally-lesioned 6-OHDA Mouse Model of Parkinson's Disease

(2012) Sherri L. Thiele et al.   Jove-Journal of Visualized Experiments

Enhancement of antinociception by coadminstration of minocycline and a non-steroidal anti-inflammatory drug indomethacin in naïve mice and murine models of LPS-induced thermal hyperalgesia and monoarthritis

(2011) Ala'a Ahmed Abu-Ghefreh et al.   BMC MUSCULOSKELETAL DISORDERS

Neuroinflammation is a key player in Parkinson’s disease and a prime target for therapy

(2010) Li Qian et al.   JOURNAL OF NEURAL TRANSMISSION

Motor complications in Parkinson's disease: Ten year follow-up study

(2010) Iria Cabo López et al.   MOVEMENT DISORDERS

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Exogenous corticosterone reduces l-DOPA-induced dyskinesia in the hemi-parkinsonian rat: Role for interleukin-1β

(2008) C.J. Barnum et al.   NEUROSCIENCE