Soluble LDL-receptor is induced by TNF-α and inhibits hepatocytic clearance of LDL-cholesterol

TNF in the liver: targeting a central player in inflammation

(2022) Gisa Tiegs et al.   Seminars in Immunopathology

Inflammatory stress signaling via NF-kB alters accessible cholesterol to upregulate SREBP2 transcriptional activity in endothelial cells

(2022) Joseph Wayne M Fowler et al.   eLife

IL-6 as a Mediator of the Association Between Traditional Risk Factors and Future Myocardial Infarction

(2021) Mulugeta M. Zegeye et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Membrane type 1 matrix metalloproteinase promotes LDL receptor shedding and accelerates the development of atherosclerosis

(2021) Adekunle Alabi et al.   Nature Communications

Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel

(2020) Jan Borén et al.   EUROPEAN HEART JOURNAL

The enigma of soluble LDLR: could inflammation be the key?

(2020) Majambu Mbikay et al.   Lipids in Health and Disease

LDL receptors, caveolae and cholesterol in endothelial dysfunction: oxLDLs accomplices or victims?

(2020) Francesca Luchetti et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair

(2019) Anthony Kusnadi et al.   IMMUNITY

Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake

(2019) Sreemoti Banerjee et al.   Scientific Reports

Validation of LDLr Activity as a Tool to Improve Genetic Diagnosis of Familial Hypercholesterolemia: A Retrospective on Functional Characterization of LDLr Variants

(2018) Asier Benito-Vicente et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Associations Between Soluble LDLR and Lipoproteins in a Caucasian Cohort and The Effect of PCSK9 Loss-of-Function

(2018) J Mayne et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Plasma inducible degrader of the LDLR, soluble low-density lipoprotein receptor, and proprotein convertase subtilisin/kexin type 9 levels as potential biomarkers of familial hypercholesterolemia in children

(2018) Josefa Girona et al.   Journal of Clinical Lipidology

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

(2017) Marc S. Sabatine et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mediation Analysis: A Practitioner's Guide

(2016) Tyler J. VanderWeele   Annual Review of Public Health

Association Between Serum Soluble Low-Density Lipoprotein Receptor Levels and Metabolic Factors in Healthy Japanese Individuals

(2014) Hisashi Shimohiro et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reticulum

(2014) Thea Bismo Strøm et al.   FEBS Open Bio

Statistical mediation analysis with a multicategorical independent variable

(2013) Andrew F. Hayes et al.   BRITISH JOURNAL OF MATHEMATICAL & STATISTICAL PSYCHOLOGY

Characterization of a naturally occurring degradation product of the LDL receptor

(2011) Kristian Tveten et al.   MOLECULAR GENETICS AND METABOLISM

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

The Västerbotten Intervention Programme: background, design and implications

(2010) Margareta Norberg et al.   Global Health Action

The LDL Receptor

(2009) Joseph L. Goldstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor

(2009) Noam Zelcer et al.   SCIENCE

Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice

(2008) Kun L. Ma et al.   HEPATOLOGY