NLRP3 inflammasome-driven IL-1β and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy

Pathophysiology of sepsis-induced cardiomyopathy

(2021) Steven M. Hollenberg et al.   Nature Reviews Cardiology

NLRP3 inflammasome as a key driver of vascular disease

(2021) Masafumi Takahashi   CARDIOVASCULAR RESEARCH

Inhibition of the NLRP3/IL‐1β axis protects against sepsis‐induced cardiomyopathy

(2021) Katharina Busch et al.   Journal of Cachexia Sarcopenia and Muscle

Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease

(2020) Antonio Abbate et al.   CIRCULATION RESEARCH

Sepsis therapies: learning from 30 years of failure of translational research to propose new leads

(2020) Jean‐Marc Cavaillon et al.   EMBO Molecular Medicine

Efficient production of large deletion and gene fragment knock-in mice mediated by genome editing with Cas9-mouse Cdt1 in mouse zygotes

(2020) Saori Mizuno-Iijima et al.   METHODS

Sepsis-Induced Cardiomyopathy: a Comprehensive Review

(2020) Michael L’Heureux et al.   Current Cardiology Reports

Interleukin-18 in Health and Disease

(2019) Koubun Yasuda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inflammasome-Independent and Atypical Processing of IL-1β Contributes to Acid Aspiration–Induced Acute Lung Injury

(2019) Yoshiko Mizushina et al.   JOURNAL OF IMMUNOLOGY

Adeno-associated Virus Vector-mediated Interleukin-10 Induction Prevents Vascular Inflammation in a Murine Model of Kawasaki Disease

(2018) Jun Nakamura et al.   Scientific Reports

Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis

(2018) Si Ming Man   Nature Reviews Gastroenterology & Hepatology

Interleukin-18 gene deletion protects against sepsis-induced cardiac dysfunction by inhibiting PP2A activity

(2017) Yoshitaka Okuhara et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Interaction of Neutrophils with Macrophages Promotes IL-1β Maturation and Contributes to Hepatic Ischemia–Reperfusion Injury

(2017) Ai Sadatomo et al.   JOURNAL OF IMMUNOLOGY

Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis

(2016) Miriam Kalbitz et al.   FASEB JOURNAL

Deletion ofNlrp3Augments Survival during Polymicrobial Sepsis by Decreasing Autophagy and Enhancing Phagocytosis

(2016) Liliang Jin et al.   JOURNAL OF IMMUNOLOGY

NLRP3 Deficiency Reduces Macrophage Interleukin-10 Production and Enhances the Susceptibility to Doxorubicin-induced Cardiotoxicity

(2016) Motoi Kobayashi et al.   Scientific Reports

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Interleukin-18 mediates interleukin-1-induced cardiac dysfunction

(2014) Stefano Toldo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

NLRP3 Inflammasome as a Novel Player in Myocardial Infarction

(2014) Masafumi Takahashi   International Heart Journal

NLRP3 Protein Deficiency Exacerbates Hyperoxia-induced Lethality through Stat3 Protein Signaling Independent of Interleukin-1β

(2014) Yoshiko Mizushina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia-Reperfusion Injury Independently of Inflammasomes

(2014) Y. Inoue et al.   JOURNAL OF IMMUNOLOGY

Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1

(2012) Olaf Groß et al.   IMMUNITY

Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury

(2011) Masanori Kawaguchi et al.   CIRCULATION

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE