Role of Hydrophobic Amino-Acid Side-Chains in the Narrow Selectivity Filter of the CFTR Chloride Channel Pore in Conductance and Selectivity

Molecular dynamics study of Cl− permeation through cystic fibrosis transmembrane conductance regulator (CFTR)

(2023) Zhi Wei Zeng et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Two positively charged amino acid side-chains in the inner vestibule of the CFTR channel pore play analogous roles in controlling anion binding and anion conductance

(2021) Paul Linsdell et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cystic fibrosis

(2021) Michal Shteinberg et al.   LANCET

Discovering the chloride pathway in the CFTR channel

(2019) Bianka Farkas et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Combining theoretical and experimental data to decipher CFTR 3D structures and functions

(2018) Brice Hoffmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Structural mechanisms of CFTR function and dysfunction

(2018) Tzyh-Chang Hwang et al.   JOURNAL OF GENERAL PHYSIOLOGY

Cystic fibrosis transmembrane conductance regulator (CFTR): Making an ion channel out of an active transporter structure

(2018) Paul Linsdell   Channels

Structure, Gating, and Regulation of the CFTR Anion Channel

(2018) László Csanády et al.   PHYSIOLOGICAL REVIEWS

Molecular structure of the ATP-bound, phosphorylated human CFTR

(2018) Zhe Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Architecture and functional properties of the CFTR channel pore

(2016) Paul Linsdell   CELLULAR AND MOLECULAR LIFE SCIENCES

Long-range coupling between the extracellular gates and the intracellular ATP binding domains of multidrug resistance protein pumps and cystic fibrosis transmembrane conductance regulator channels

(2016) Shipeng Wei et al.   FASEB JOURNAL

Interactions between permeant and blocking anions inside the CFTR chloride channel pore

(2015) Paul Linsdell   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cysteine Scanning of CFTR’s First Transmembrane Segment Reveals Its Plausible Roles in Gating and Permeation

(2013) Xiaolong Gao et al.   BIOPHYSICAL JOURNAL

Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore

(2010) Jing-Jun Zhou et al.   JOURNAL OF GENERAL PHYSIOLOGY

Novel Residues Lining the CFTR Chloride Channel Pore Identified by Functional Modification of Introduced Cysteines

(2009) Mohammad Fatehi et al.   JOURNAL OF MEMBRANE BIOLOGY