Kruppel-Like Factor 5 Acetylation Upregulates Runx2 Expression and Accelerates the Dedifferentiation Process of Chondrocyte in Monolayer Culture

The mechanism of Danzikang Knee Granule in regulating the chondrogenic differentiation of mesenchymal stem cells based on TGF-β signaling pathway in cartilage repair in knee osteoarthritis

(2022) Yu Xiaoyu et al.   CELLULAR AND MOLECULAR BIOLOGY

Hyaluronic Acid Modified Curcumin-Loaded Chitosan Nanoparticles Inhibit Chondrocyte Apoptosis to Attenuate Osteoarthritis via Upregulation of Activator Protein 1 and RUNX Family Transcription Factor 2

(2022) Jian Wang et al.   Journal of Biomedical Nanotechnology

The effect of synthesized cartilage tissue from human adipose-derived mesenchymal stem cells in orthopedic spine surgery in patients with osteoarthritis

(2021) Tang Weijie et al.   CELLULAR AND MOLECULAR BIOLOGY

Krϋppel-like factors (KLFs) in renal physiology and disease

(2019) Madhavi J. Rane et al.   EBioMedicine

EGR1 promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling

(2019) Xuewu Sun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Development of a simple osteoarthritis model useful to predict in vitro the anti-hypertrophic action of drugs

(2019) Lyess Allas et al.   LABORATORY INVESTIGATION

HDAC-mediated deacetylation of KLF5 associates with its proteasomal degradation

(2018) Ran Tao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Runx2, an inducer of osteoblast and chondrocyte differentiation

(2018) Toshihisa Komori   HISTOCHEMISTRY AND CELL BIOLOGY

Smad4 deficiency impairs chondrocyte hypertrophy via the Runx2 transcription factor in mouse skeletal development

(2018) Jianyun Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional control of chondrocyte specification and differentiation

(2017) Chia-Feng Liu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Targeting Kruppel-Like Factor 5 (KLF5) for Cancer Therapy

(2015) Yu Gao et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Osteoarthritis Pathogenesis: A Review of Molecular Mechanisms

(2014) Bingjiang Xia et al.   CALCIFIED TISSUE INTERNATIONAL

Interruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells

(2014) Xin Li et al.   INTERNATIONAL JOURNAL OF CANCER

Nkx3.2-induced suppression of Runx2 is a crucial mediator of hypoxia-dependent maintenance of chondrocyte phenotypes

(2011) Yoshitaka Kawato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HDAC2 phosphorylation-dependent Klf5 deacetylation and RARα acetylation induced by RAR agonist switch the transcription regulatory programs of p21 in VSMCs

(2011) Bin Zheng et al.   CELL RESEARCH

Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?

(2011) P.M. van der Kraan et al.   OSTEOARTHRITIS AND CARTILAGE

Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases

(2009) Jin-Tang Dong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pro-proliferative Factor KLF5 Becomes Anti-proliferative in Epithelial Homeostasis upon Signaling-mediated Modification

(2008) Peng Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Krüppel-like Factor 5 Causes Cartilage Degradation through Transactivation of Matrix Metalloproteinase 9

(2008) Yusuke Shinoda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endochondral ossification: How cartilage is converted into bone in the developing skeleton

(2007) E.J. Mackie et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY