Prognostic and immunological role of acetaldehyde dehydrogenase 1B1 in human tumors: A pan-cancer analysis

Anti-CSF-1R emactuzumab in combination with anti-PD-L1 atezolizumab in advanced solid tumor patients naïve or experienced for immune checkpoint blockade

(2022) Carlos Gomez-Roca et al.   Journal for ImmunoTherapy of Cancer

High Expression of p62 and ALDH1A3 Is Associated With Poor Prognosis in Luminal B Breast Cancer

(2022) AYAKA OZAKI et al.   ANTICANCER RESEARCH

Cancer germline antigen gene MAGEB2 promotes cell invasion and correlates with immune microenvironment and immunotherapeutic efficiency in laryngeal cancer

(2022) Jie Cui et al.   CLINICAL IMMUNOLOGY

Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1

(2022) Zhiping Feng et al.   Nature Chemical Biology

Concomitant medication of cetirizine in advanced melanoma could enhance anti-PD-1 efficacy by promoting M1 macrophages polarization

(2022) Domenico Mallardo et al.   Journal of Translational Medicine

Advancing beyond the twists and turns of T cell exhaustion in cancer

(2022) Verena van der Heide et al.   Science Translational Medicine

Development and Validation of Epigenetic Signature Predict Survival for Patients with Laryngeal Squamous Cell Carcinoma

(2021) Jie Cui et al.   DNA AND CELL BIOLOGY

Aldehyde Dehydrogenase 1B1 Is Associated with Altered Cell Morphology, Proliferation, Migration and Chemosensitivity in Human Colorectal Adenocarcinoma Cells

(2021) Ilias Tsochantaridis et al.   Biomedicines

Web-Based Survival Analysis Tool Tailored for Medical Research (KMplot): Development and Implementation

(2021) András Lánczky et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

Immunogenomic pan-cancer landscape reveals immune escape mechanisms and immunoediting histories

(2021) Shinichi Mizuno et al.   Scientific Reports

The foundations of immune checkpoint blockade and the ipilimumab approval decennial

(2021) Alan J. Korman et al.   NATURE REVIEWS DRUG DISCOVERY

Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses

(2020) Jesse M. Jaynes et al.   Science Translational Medicine

Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression

(2020) Samir Devalaraja et al.   CELL

TIMER2.0 for analysis of tumor-infiltrating immune cells

(2020) Taiwen Li et al.   NUCLEIC ACIDS RESEARCH

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis

(2019) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Immune evasion before tumour invasion in early lung squamous carcinogenesis

(2019) Céline Mascaux et al.   NATURE

Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell–mediated tumor regression

(2019) Anders Etzerodt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer

(2019) Ekaterina Mameishvili et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aldehyde Dehydrogenase Inhibitors for Cancer Therapeutics

(2019) Saketh S. Dinavahi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Aldehyde dehydrogenase in regulatory T-cell development, immunity and cancer

(2018) Christopher G. Bazewicz et al.   IMMUNOLOGY

Gestational high-fat diet and bisphenol A exposure heightens mammary cancer risk

(2017) Yuet-Kin Leung et al.   ENDOCRINE-RELATED CANCER

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity

(2017) Sydney R. Gordon et al.   NATURE

Upregulation of ALDH1B1 promotes tumor progression in osteosarcoma

(2017) Xin Wang et al.   Oncotarget

Aldehyde dehydrogenase 1 (ALDH1) isoform expression and potential clinical implications in hepatocellular carcinoma

(2017) Cheng–kun Yang et al.   PLoS One

Aldehyde Dehydrogenase Plays a Pivotal Role in the Maintenance of Stallion Sperm Motility1

(2016) Zamira Gibb et al.   BIOLOGY OF REPRODUCTION

Aldehyde dehydrogenase 3A1 is robustly upregulated in gastric cancer stem-like cells and associated with tumorigenesis

(2016) Di Wu et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial

(2016) Timothy M Nywening et al.   LANCET ONCOLOGY

Aldehyde Dehydrogenase 1B1 as a Modulator of Pancreatic Adenocarcinoma

(2016) Surendra Singh et al.   PANCREAS

Mining distinct aldehyde dehydrogenase 1 (ALDH1) isoenzymes in gastric cancer

(2016) Jia-Xin Shen et al.   Oncotarget

ALDH1B1 links alcohol consumption and diabetes

(2015) Surendra Singh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

(2015) Suzanne L. Topalian et al.   CANCER CELL

Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice

(2015) Vivian Anastasiou et al.   DIABETOLOGIA

ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways

(2015) Surendra Singh et al.   PLoS One

Impaired one carbon metabolism and DNA methylation in alcohol toxicity

(2014) Inna I. Kruman et al.   JOURNAL OF NEUROCHEMISTRY

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Aldehyde Dehydrogenase 1B1: Molecular Cloning and Characterization of a Novel Mitochondrial Acetaldehyde-Metabolizing Enzyme

(2010) D. Stagos et al.   DRUG METABOLISM AND DISPOSITION

Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily

(2008) Satori A Marchitti et al.   Expert Opinion on Drug Metabolism & Toxicology

Polymorphisms in Methionine Synthase, Methionine Synthase Reductase and Serine Hydroxymethyltransferase, Folate and Alcohol Intake, and Colon Cancer Risk

(2008) Susan E. Steck et al.   Journal of Nutrigenetics and Nutrigenomics

ALDH1A1 and ALDH3A1 expression in lung cancers: Correlation with histologic type and potential precursors

(2007) Miten Patel et al.   LUNG CANCER