An ex vivo lung model to study bronchioles infected with Pseudomonas aeruginosa biofilms

Cystic fibrosis

(2016) J Stuart Elborn   LANCET

Iron acquisition in the cystic fibrosis lung and potential for novel therapeutic strategies

(2016) Jean Tyrrell et al.   MICROBIOLOGY-SGM

RNASeq Based Transcriptional Profiling of Pseudomonas aeruginosa PA14 after Short- and Long-Term Anoxic Cultivation in Synthetic Cystic Fibrosis Sputum Medium

(2016) Muralidhar Tata et al.   PLoS One

The Limitations of In Vitro Experimentation in Understanding Biofilms and Chronic Infection

(2015) Aled E.L. Roberts et al.   JOURNAL OF MOLECULAR BIOLOGY

Essential genome ofPseudomonas aeruginosain cystic fibrosis sputum

(2015) Keith H. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Sweeps and Parallel Pathoadaptation Drive Pseudomonas aeruginosa Evolution in the Cystic Fibrosis Lung

(2015) Julio Diaz Caballero et al.   mBio

Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection

(2015) Sophie E. Darch et al.   Scientific Reports

Cystic fibrosis-adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses

(2015) S. L. LaFayette et al.   Science Advances

Development of anEx VivoPorcine Lung Model for Studying Growth, Virulence, and Signaling of Pseudomonas aeruginosa

(2014) Freya Harrison et al.   INFECTION AND IMMUNITY

Polymorphonuclear Leukocytes Restrict Growth of Pseudomonas aeruginosa in the Lungs of Cystic Fibrosis Patients

(2014) Kasper N. Kragh et al.   INFECTION AND IMMUNITY

Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure

(2014) Ashley G. Henderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Polybacterial human disease: the ills of social networking

(2014) Francesca L. Short et al.   TRENDS IN MICROBIOLOGY

Animal models of human disease: Challenges in enabling translation

(2013) Paul McGonigle et al.   BIOCHEMICAL PHARMACOLOGY

NMR HRMAS spectroscopy of lung biopsy samples: Comparison study between human, pig, rat, and mouse metabolomics

(2013) Malika A. Benahmed et al.   MAGNETIC RESONANCE IN MEDICINE

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The in vivo biofilm

(2013) Thomas Bjarnsholt et al.   TRENDS IN MICROBIOLOGY

The pig: a model for human infectious diseases

(2011) François Meurens et al.   TRENDS IN MICROBIOLOGY

Ecological succession in long-term experimentally evolved biofilms produces synergistic communities

(2010) Steffen R Poltak et al.   ISME Journal

An ex vivo swine tracheal organ culture for the study of influenza infection

(2009) Sandro F. Nunes et al.   Influenza and Other Respiratory Viruses

Pseudomonas aeruginosabiofilms in the respiratory tract of cystic fibrosis patients

(2009) Thomas Bjarnsholt et al.   PEDIATRIC PULMONOLOGY

Animal models of chronic lung infection with Pseudomonas aeruginosa: useful tools for cystic fibrosis studies

(2008) I Kukavica-Ibrulj et al.   LABORATORY ANIMALS