Copper-triggered three-component reaction of CF3CHN2, nitriles, and aldehydes: highly diastereoselective synthesis of CF3-substituted oxazolines and vicinal amino alcohols

[3 + 2] Cycloaddition of arynes with CF 3 CHN 2 : Access to 3-trifluoromethyl-1 H -indazoles

(2015) Long Sun et al.   JOURNAL OF FLUORINE CHEMISTRY

Studies on Electrophilic Cyclization ofN-(Buta-2,3-dienyl)amides withN-Bromosuccinimide and its Applications

(2014) Nan Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

An Ylide Transformation of Rhodium(I) Carbene: Enantioselective Three-Component Reaction through Trapping of Rhodium(I)-Associated Ammonium Ylides by β-Nitroacrylates

(2014) Xiaochu Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereoselective Synthesis of Vicinally Bis(trifluoromethylated) Alkylboron Compounds through Successive Insertions of 2,2,2-Trifluorodiazoethane

(2014) Gary A. Molander et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed One-Pot Denitrogenative-Dehydrogenative-Decarboxylative Coupling of β-Ketoacids with Trifluorodiazoethane: Facile Access to Trifluoromethylated Aldol Products

(2014) Heng-Ying Xiong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic One-Pot Synthesis of Highly Substituted Pyridazines from Morita-Baylis-Hillman Carbonates and Diazo Compounds

(2014) Haibin Mao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Switchable 2,2,2-Trifluoroethylation andgem-Difluorovinylation of Organoboronic Acids with 2,2,2-Trifluorodiazoethane

(2014) Guojiao Wu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Trifluoromethyl-Substituted 3-Azabicyclo[n.1.0]alkanes: Advanced Building Blocks for Drug Discovery

(2014) Olexiy S. Artamonov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of CF3-Containing 3,3′-Cyclopropyl Spirooxindoles by Sequential [3 + 2] Cycloaddition/Ring Contraction of Ylideneoxindoles with 2,2,2-Trifluorodiazoethane

(2014) Tian-Ren Li et al.   JOURNAL OF ORGANIC CHEMISTRY

A Direct Copper-Promoted Three-Component Entry to Trifluoromethylketoximes

(2014) Shuai Wang et al.   ORGANIC LETTERS

Regioselective Cycloaddition of Trifluorodiazoethane with Electron-Deficient Allenic Esters and Ketones: Access to CF3-Substituted Pyrazolines and Pyrazoles

(2014) Fa-Guang Zhang et al.   ORGANIC LETTERS

Synthesis and Applications of α-Trifluoromethylated Alkylboron Compounds

(2013) O. Andreea Argintaru et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diversity-Oriented Three-Component Reactions of Diazo Compounds with Anilines and 4-Oxo-Enoates

(2013) Changcheng Jing et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver-Mediated Cycloaddition of Alkynes with CF3CHN2: Highly Regioselective Synthesis of 3-Trifluoromethylpyrazoles

(2013) Feng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Trifluoromethylated Isoxazolidines: 1,3-Dipolar Cycloaddition of Nitrosoarenes, (Trifluoromethyl)diazomethane, and Alkenes

(2013) Gary A. Molander et al.   ORGANIC LETTERS

A Facile Parallel Synthesis of Trifluoroethyl-Substituted Alkynes

(2012) Cui-Bo Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Brønsted acid-catalyzed diastereo- and enantioselective synthesis of CF3-substituted aziridines

(2012) Zhuo Chai et al.   CHEMICAL COMMUNICATIONS

Chemistry and Biology Of Multicomponent Reactions

(2012) Alexander Dömling et al.   CHEMICAL REVIEWS

Recent developments in asymmetric multicomponent reactions

(2012) Corien de Graaff et al.   CHEMICAL SOCIETY REVIEWS

A highly diastereoselective three-component tandem 1,4-conjugated addition–cyclization reaction to multisubstituted pyrrolidines

(2012) Xia Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Brønsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enantioenriched Structurally Diverse Nitrogenous Heterocycles

(2011) Jie Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of Trifluoroethyl-Substituted Ketones from Aldehydes and Cyclohexanones

(2011) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity

(2011) Eelco Ruijter et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Update 1 of:C2-Symmetric Chiral Bis(oxazoline) Ligands in Asymmetric Catalysis

(2011) Giovanni Desimoni et al.   CHEMICAL REVIEWS

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

Iron-Catalyzed Preparation of Trifluoromethyl Substituted Vinyl- and Alkynylcyclopropanes

(2011) Bill Morandi et al.   ORGANIC LETTERS

Enantioselective Cobalt-Catalyzed Preparation of Trifluoromethyl-Substituted Cyclopropanes

(2010) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Cyclopropenation of Alkynes: Synthesis of Trifluoromethyl-Substituted Cyclopropenes

(2010) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

(2010) Jing Nie et al.   CHEMICAL REVIEWS

Current strategies for diversity-oriented synthesis

(2010) Sivaraman Dandapani et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Trifluoromethyl-substituted cyclopropanes

(2010) Oleksandr O. Grygorenko et al.   TETRAHEDRON

Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules

(2010) Warren R.J.D. Galloway et al.   Nature Communications

Strategies for Innovation in Multicomponent Reaction Design

(2009) Bruce Ganem   ACCOUNTS OF CHEMICAL RESEARCH

Iron-Catalyzed Cyclopropanation with Trifluoroethylamine Hydrochloride and Olefins in Aqueous Media: In Situ Generation of Trifluoromethyl Diazomethane

(2009) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Poly(2-oxazoline)s: A Polymer Class with Numerous Potential Applications

(2009) Richard Hoogenboom   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-pot three-component tandem reaction of diazo compounds with anilines and unsaturated ketoesters: a novel synthesis of 2,3-dihydropyrrole derivatives

(2009) Yingguang Zhu et al.   CHEMICAL COMMUNICATIONS

Natural Product Synthesis Using Multicomponent Reaction Strategies

(2009) Barry B. Touré et al.   CHEMICAL REVIEWS

Recent Applications of Oxazoline-Containing Ligands in Asymmetric Catalysis

(2009) Gráinne C. Hargaden et al.   CHEMICAL REVIEWS

Applications of Multicomponent Reactions to the Synthesis of Diverse Heterocyclic Scaffolds

(2009) James D. Sunderhaus et al.   CHEMISTRY-A EUROPEAN JOURNAL

Dibutyl 2-(trifluoromethyl)cyclopropylboronate as a useful (trifluoromethyl)cyclopropyl donor: application to antagonists of TRPV1

(2009) Matthew A.J. Duncton et al.   TETRAHEDRON LETTERS

Synthesis of Trifluoromethyl‐Substituted Proline Analogues as19F NMR Labels for Peptides in the Polyproline II Conformation

(2008) Pavel K. Mykhailiuk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS