Survival and division fate programs are preserved but retuned during the naïve to memory CD8+ T‐cell transition

Functional T cells are capable of supernumerary cell division and longevity

(2023) Andrew G. Soerens et al.   NATURE

CD8+ T-Cell Memory: The Why, the When, and the How

(2021) Stephen J. Turner et al.   Cold Spring Harbor Perspectives in Biology

Antigen-Specific CD4+ T Cells Exhibit Distinct Kinetic and Phenotypic Patterns During Primary and Secondary Responses to Infection

(2020) Deepali Malhotra et al.   Frontiers in Immunology

IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level

(2017) Byron B. Au-Yeung et al.   JOURNAL OF IMMUNOLOGY

Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy

(2017) Gail D. Sckisel et al.   Journal for ImmunoTherapy of Cancer

CD28 days later: Resurrecting costimulation for CD8+memory T cells

(2016) Verena van der Heide et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interrupting CD28 costimulation before antigen rechallenge affects CD8+T-cell expansion and effector functions during secondary response in mice

(2016) Monika Fröhlich et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Myc-dependent division timer complements a cell-death timer to regulate T cell and B cell responses

(2016) Susanne Heinzel et al.   NATURE IMMUNOLOGY

T-cell stimuli independently sum to regulate an inherited clonal division fate

(2016) J. M. Marchingo et al.   Nature Communications

Serial Transfer of Single-Cell-Derived Immunocompetence Reveals Stemness of CD8+ Central Memory T Cells

(2014) Patricia Graef et al.   IMMUNITY

Memory CD8+T cells exhibit increased antigen threshold requirements for recall proliferation

(2014) Erin R. Mehlhop-Williams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Lymphopenic Environment of CD132 (Common  -Chain)-Deficient Hosts Elicits Rapid Homeostatic Proliferation of Naive T Cells via IL-15

(2014) C. Ramsey et al.   JOURNAL OF IMMUNOLOGY

The Longevity of Memory CD8 T Cell Responses after Repetitive Antigen Stimulations

(2014) D. Rai et al.   JOURNAL OF IMMUNOLOGY

Bystander Activation and Anti-Tumor Effects of CD8+ T Cells Following Interleukin-2 Based Immunotherapy Is Independent of CD4+ T Cell Help

(2014) Arta M. Monjazeb et al.   PLoS One

Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion

(2014) J. M. Marchingo et al.   SCIENCE

Influenza infection results in local expansion of memory CD8+T cells with antigen non-specific phenotype and function

(2013) Gail D. Sckisel et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Unique Features of Naive CD8+ T Cell Activation by IL-2

(2013) J.-H. Cho et al.   JOURNAL OF IMMUNOLOGY

Heterogeneous Differentiation Patterns of Individual CD8+ T Cells

(2013) C. Gerlach et al.   SCIENCE

Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals

(2013) Paul Koenen et al.   Nature Communications

The smallest unit: effector and memory CD8+ T cell differentiation on the single cell level

(2013) Veit R. Buchholz et al.   Frontiers in Immunology

Distinct mechanisms mediate naive and memory CD8 T-cell tolerance

(2012) E. R. Jellison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Population Dynamics of Naive and Memory CD8 T Cell Responses after Antigen Stimulations In Vivo

(2011) M. D. Martin et al.   JOURNAL OF IMMUNOLOGY

Quick to remember, slow to forget: rapid recall responses of memory CD8+ T cells

(2009) Joanna R DiSpirito et al.   CELL RESEARCH

Complete but curtailed T-cell response to very low-affinity antigen

(2009) Dietmar Zehn et al.   NATURE

A single-cell pedigree analysis of alternative stochastic lymphocyte fates

(2009) E. D. Hawkins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Memory T cells need CD28 costimulation to remember

(2009) Alina C. Boesteanu et al.   SEMINARS IN IMMUNOLOGY

Homeostasis of Naive and Memory T Cells

(2008) Charles D. Surh et al.   IMMUNITY

Tentative T Cells: Memory Cells Are Quick to Respond, but Slow to Divide

(2008) Jason K. Whitmire et al.   PLoS Pathogens