From the outer ear to the nerve: A complete computer model of the peripheral auditory system

The reticular lamina and basilar membrane vibrations in the transverse direction in the basal turn of the living gerbil cochlea

(2022) Wenxuan He et al.   Scientific Reports

Functional subgroups of cochlear inner hair cell ribbon synapses differently modulate their EPSC properties in response to stimulation.

(2021) Mamiko Niwa et al.   JOURNAL OF NEUROPHYSIOLOGY

The speed of the hair cell mechanotransducer channel revealed by fluctuation analysis

(2021) Maryline Beurg et al.   JOURNAL OF GENERAL PHYSIOLOGY

The global hearing therapeutic pipeline: 2021

(2021) Beverley Isherwood et al.   DRUG DISCOVERY TODAY

Novel oral multifunctional antioxidant prevents noise-induced hearing loss and hair cell loss

(2020) G.D. Chen et al.   HEARING RESEARCH

Presbycusis: An Update on Cochlear Mechanisms and Therapies

(2020) Jing Wang et al.   Journal of Clinical Medicine

Complex nonlinear capacitance in outer hair cell macro-patches: effects of membrane tension

(2020) Joseph Santos-Sacchi et al.   Scientific Reports

Simulating diffusion from a cluster of point sources using propagation integrals

(2020) Dirk Gillespie   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Optimized Tuning of Auditory Inner Hair Cells to Encode Complex Sound through Synergistic Activity of Six Independent K+ Current Entities

(2020) Marlen Dierich et al.   Cell Reports

The interplay of organ-of-Corti vibrational modes, not tectorial- membrane resonance, sets outer-hair-cell stereocilia phase to produce cochlear amplification

(2020) John J. Guinan   HEARING RESEARCH

The cochlear ear horn: geometric origin of tonotopic variations in auditory signal processing

(2020) Alessandro Altoè et al.   Scientific Reports

The influence of distributed source regions in the formation of the nonlinear distortion component of cubic distortion-product otoacoustic emissions

(2019) Václav Vencovský et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

Unified cochlear model for low- and high-frequency mammalian hearing

(2019) Aritra Sasmal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A phenomenological model of the synapse between the inner hair cell and auditory nerve: Implications of limited neurotransmitter release sites

(2018) Ian C. Bruce et al.   HEARING RESEARCH

The effects of the activation of the inner-hair-cell basolateral K + channels on auditory nerve responses

(2018) Alessandro Altoè et al.   HEARING RESEARCH

Computational modeling of the human auditory periphery: Auditory-nerve responses, evoked potentials and hearing loss

(2018) Sarah Verhulst et al.   HEARING RESEARCH

Cochlear amplification and tuning depend on the cellular arrangement within the organ of Corti

(2018) Hamid Motallebzadeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clustered Ca2+ Channels Are Blocked by Synaptic Vesicle Proton Release at Mammalian Auditory Ribbon Synapses

(2018) Philippe F.Y. Vincent et al.   Cell Reports

Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses

(2017) Nicolas Michalski et al.   eLife

Finite element modelling of cochlear electrical coupling

(2016) Paul D. Teal et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

Hair cells use active zones with different voltage dependence of Ca2+influx to decompose sounds into complementary neural codes

(2016) Tzu-Lun Ohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resolving the structure of inner ear ribbon synapses with STED microscopy

(2015) Mark A. Rutherford   SYNAPSE

Elementary properties of Ca2+ channels and their influence on multivesicular release and phase-locking at auditory hair cell ribbon synapses

(2015) Jacopo Magistretti et al.   Frontiers in Cellular Neuroscience

Presynaptic nanodomains: a tale of two synapses

(2015) Lu-Yang Wang et al.   Frontiers in Cellular Neuroscience

Membrane properties specialize mammalian inner hair cells for frequency or intensity encoding

(2015) Stuart L Johnson   eLife

The Effects of HCN and KLT Ion Channels on Adaptation and Refractoriness in a Stochastic Auditory Nerve Model

(2014) Mohamed H. Negm et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

A Model of Synaptic Vesicle-Pool Depletion and Replenishment Can Account for the Interspike Interval Distributions and Nonrenewal Properties of Spontaneous Spike Trains of Auditory-Nerve Fibers

(2014) A. J. Peterson et al.   JOURNAL OF NEUROSCIENCE

Exocytotic Machineries of Vestibular Type I and Cochlear Ribbon Synapses Display Similar Intrinsic Otoferlin-Dependent Ca2+ Sensitivity But a Different Coupling to Ca2+ Channels

(2014) P. F. Y. Vincent et al.   JOURNAL OF NEUROSCIENCE

Updated parameters and expanded simulation options for a model of the auditory periphery

(2014) Muhammad S. A. Zilany et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

Fine Tuning of CaV1.3 Ca2+ Channel Properties in Adult Inner Hair Cells Positioned in the Most Sensitive Region of the Gerbil Cochlea

(2014) Valeria Zampini et al.   PLoS One

Detection of Cochlear Amplification and Its Activation

(2013) Wei Dong et al.   BIOPHYSICAL JOURNAL

Concurrent Maturation of Inner Hair Cell Synaptic Ca2+ Influx and Auditory Nerve Spontaneous Activity around Hearing Onset in Mice

(2013) A. B. Wong et al.   JOURNAL OF NEUROSCIENCE

TMHS Is an Integral Component of the Mechanotransduction Machinery of Cochlear Hair Cells

(2012) Wei Xiong et al.   CELL

Transmission of cochlear distortion products as slow waves: A comparison of experimental and model data

(2012) Aleš Vetešník et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

Nonlinear time-domain cochlear model for transient stimulation and human otoacoustic emission

(2012) Sarah Verhulst et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

An Improved Model for the Rate-Level Functions of Auditory-Nerve Fibers

(2011) P. Heil et al.   JOURNAL OF NEUROSCIENCE

Prestin-Driven Cochlear Amplification Is Not Limited by the Outer Hair Cell Membrane Time Constant

(2011) Stuart L. Johnson et al.   NEURON

Reduced Electromotility of Outer Hair Cells Associated with Connexin-Related Forms of Deafness: An In silico Study of a Cochlear Network Mechanism

(2010) Pavel Mistrík et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Nanodomain Control of Exocytosis Is Responsible for the Signaling Capability of a Retinal Ribbon Synapse

(2010) T. Jarsky et al.   JOURNAL OF NEUROSCIENCE

Hearing Impairment: A Panoply of Genes and Functions

(2010) Amiel A. Dror et al.   NEURON

Bassoon and the Synaptic Ribbon Organize Ca2+ Channels and Vesicles to Add Release Sites and Promote Refilling

(2010) Thomas Frank et al.   NEURON

Evaluation of Stochastic Differential Equation Approximation of Ion Channel Gating Models

(2009) Ian C. Bruce   ANNALS OF BIOMEDICAL ENGINEERING

Elementary properties of CaV1.3 Ca2+channels expressed in mouse cochlear inner hair cells

(2009) Valeria Zampini et al.   JOURNAL OF PHYSIOLOGY-LONDON

A phenomenological model of the synapse between the inner hair cell and auditory nerve: Long-term adaptation with power-law dynamics

(2009) Muhammad S. A. Zilany et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

Measurements of stapes velocity in live human ears

(2008) Wade Chien et al.   HEARING RESEARCH

Biophysical properties of CaV1.3 calcium channels in gerbil inner hair cells

(2008) Stuart L. Johnson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Three-dimensional current flow in a large-scale model of the cochlea and the mechanism of amplification of sound

(2008) P. Mistrik et al.   Journal of the Royal Society Interface