Microfracture technique combined with mesenchymal stem cells inducer represses miR-708-5p to target special at-rich sequence-binding protein 2 to drive cartilage repair and regeneration in rabbit knee osteoarthritis

MicroRNA-199-3p up-regulation enhances chondrocyte proliferation and inhibits apoptosis in knee osteoarthritis via DNMT3A repression

(2021) Wenqi Gu et al.   INFLAMMATION RESEARCH

LINC02288 promotes chondrocyte apoptosis and inflammation through miR‐374a‐3p targeting RTN3

(2021) Qiwei Fu et al.   JOURNAL OF GENE MEDICINE

Special AT‐rich sequence‐binding protein 2 ( Satb2 ) synergizes with Bmp9 and is essential for osteo/odontogenic differentiation of mouse incisor mesenchymal stem cells

(2021) Qiuman Chen et al.   CELL PROLIFERATION

SNHG5 protects chondrocytes in interleukin‐1β‐stimulated osteoarthritis via regulating miR‐181a‐5p/TGFBR3 axis

(2021) Yang Yue et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

The mechanism of aerobic exercise combined with glucosamine therapy and circUNK in improving knee osteoarthritis in rabbits

(2021) Lei Fang et al.   LIFE SCIENCES

Reprogrammed Synovial Fluid-Derived Mesenchymal Stem/Stromal Cells Acquire Enhanced Therapeutic Potential for Articular Cartilage Repair

(2021) Brian E. Walczak et al.   Cartilage

Efficacy and Mechanism of Electroacupuncture Treatment of Rabbits With Different Degrees of Knee Osteoarthritis: A Study Based on Synovial Innate Immune Response

(2021) Anmin Ruan et al.   Frontiers in Physiology

Expression profiling of mitochondria-associated microRNAs during osteogenic differentiation of human MSCs

(2021) Hongjun Zheng et al.   BONE

Electroacupuncture alleviates cartilage degradation: Improvement in cartilage biomechanics via pain relief and potentiation of muscle function in a rabbit model of knee osteoarthritis

(2020) Xiaowei Shi et al.   BIOMEDICINE & PHARMACOTHERAPY

Risk factors and the natural history of accelerated knee osteoarthritis: a narrative review

(2020) Jeffrey B. Driban et al.   BMC MUSCULOSKELETAL DISORDERS

Long non-coding RNA H19 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by regulating microRNA-140-5p/SATB2 axis

(2020) Hu Bi et al.   JOURNAL OF BIOSCIENCES

Chrysin Attenuates the NLRP3 Inflammasome Cascade to Reduce Synovitis and Pain in KOA Rats

(2020) Taiyang Liao et al.   Drug Design Development and Therapy

The effect of distance between holes on the structural stability of subchondral bone in microfracture surgery: a finite element model study

(2020) Xiang Yun Yin et al.   BMC MUSCULOSKELETAL DISORDERS

SATB2 is a novel biomarker and therapeutic target for cancer

(2020) Sanjit K. Roy et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Synergistic effects of miR-708-5p and miR-708-3p accelerate the progression of osteoporosis

(2020) Ruran Wang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Exosome-mediated delivery of kartogenin for chondrogenesis of synovial fluid-derived mesenchymal stem cells and cartilage regeneration

(2020) Xiao Xu et al.   BIOMATERIALS

Genome‐wide microRNA screening reveals miR‐582‐5p as a mesenchymal stem cell‐specific microRNA in subchondral bone of the human knee joint

(2019) Pinger Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Intra-articular injection of hUC-MSCs expressing miR-140-5p induces cartilage self-repairing in the rat osteoarthritis

(2019) Yiyun Geng et al.   JOURNAL OF BONE AND MINERAL METABOLISM

The combination of microfracture with induction of Wnt / β- Catenin pathway, leads to enhanced cartilage regeneration

(2019) Nikitas P. Schizas et al.   Journal of Orthopaedic Surgery and Research

Sodium butyrate abolishes the degradation of type II collagen in human chondrocytes

(2018) Wang Bo et al.   BIOMEDICINE & PHARMACOTHERAPY

Efficacy of intra-articular hypertonic dextrose prolotherapy versus normal saline for knee osteoarthritis: a protocol for a triple-blinded randomized controlled trial

(2018) Regina Wing Shan Sit et al.   BMC Complementary and Alternative Medicine

Epidemiology of osteoarthritis

(2018) Ernest R. Vina et al.   CURRENT OPINION IN RHEUMATOLOGY

miR-708-5p promotes fibroblast–like synoviocytes' cell apoptosis and ameliorates rheumatoid arthritis by inhibition of Wnt3a/β-catenin pathway

(2018) Jie Wu et al.   Drug Design Development and Therapy

Knee osteoarthritis has doubled in prevalence since the mid-20th century

(2017) Ian J. Wallace et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allogeneic MSCs and Recycled Autologous Chondrons Mixed in a One-Stage Cartilage Cell Transplantion: A First-in-Man Trial in 35 Patients

(2017) Tommy S. de Windt et al.   STEM CELLS

MiR-708 promotes steroid-induced osteonecrosis of femoral head, suppresses osteogenic differentiation by targeting SMAD3

(2016) Cheng Hao et al.   Scientific Reports

Full-thickness cartilage defects are repaired via a microfracture technique and intraarticular injection of the small-molecule compound kartogenin

(2015) Xingquan Xu et al.   ARTHRITIS RESEARCH & THERAPY

One-Step Repair for Cartilage Defects in a Rabbit Model

(2014) Linghui Dai et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

The global burden of hip and knee osteoarthritis: estimates from the Global Burden of Disease 2010 study

(2014) Marita Cross et al.   ANNALS OF THE RHEUMATIC DISEASES

FOXO3A Regulation by miRNA-29a Controls Chondrogenic Differentiation of Mesenchymal Stem Cells and Cartilage Formation

(2014) David Guérit et al.   STEM CELLS AND DEVELOPMENT

SATB2 is a novel marker of osteoblastic differentiation in bone and soft tissue tumours

(2013) James R Conner et al.   HISTOPATHOLOGY

A Stem Cell-Based Approach to Cartilage Repair

(2012) K. Johnson et al.   SCIENCE

Role of a LIF antagonist in LIF and OSM induced MMP-1, MMP-3, and TIMP-1 expression by primary articular chondrocytes

(2009) Aradhana Upadhyay et al.   CYTOKINE

Drilling and microfracture lead to different bone structure and necrosis during bone-marrow stimulation for cartilage repair

(2009) Hongmei Chen et al.   JOURNAL OF ORTHOPAEDIC RESEARCH