Genome‐wide microRNA screening reveals miR‐582‐5p as a mesenchymal stem cell‐specific microRNA in subchondral bone of the human knee joint

MicroRNA-19a promotes cell viability and migration of chondrocytes via up-regulating SOX9 through NF-κB pathway

(2018) Chuandong Yu et al.   BIOMEDICINE & PHARMACOTHERAPY

Blocking PI3K/AKT signaling inhibits bone sclerosis in subchondral bone and attenuates post-traumatic osteoarthritis

(2018) Chuangxin Lin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Transforming growth factor-beta1 promotes articular cartilage repair through canonical Smad and Hippo pathways in bone mesenchymal stem cells

(2018) Jun Ying et al.   LIFE SCIENCES

miR-582-5p inhibits invasion and migration of salivary adenoid cystic carcinoma cells by targeting FOXC1

(2017) Wei-Wei Wang et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Subchondral mesenchymal stem cells from osteoarthritic knees display high osteogenic differentiation capacity through microRNA-29a regulation of HDAC4

(2017) Wei-Shiung Lian et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Inhibition of the TGF-β1/Smad signaling pathway protects against cartilage injury and osteoarthritis in a rat model

(2017) Yong-Jian Wang et al.   LIFE SCIENCES

Utility of circulating serum miRNAs as biomarkers of early cartilage degeneration in animal models of post-traumatic osteoarthritis and inflammatory arthritis

(2017) L.H.W. Kung et al.   OSTEOARTHRITIS AND CARTILAGE

Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma

(2017) Vincenzo Petrozza et al.   Oncotarget

MiR-146b is down-regulated during the chondrogenic differentiation of human bone marrow derived skeletal stem cells and up-regulated in osteoarthritis

(2017) Emma Budd et al.   Scientific Reports

Systematic Identification, Characterization and Target Gene Analysis of microRNAs Involved in Osteoarthritis Subchondral Bone Pathogenesis

(2016) Indira Prasadam et al.   CALCIFIED TISSUE INTERNATIONAL

MiR-27a is Essential for the Shift from Osteogenic Differentiation to Adipogenic Differentiation of Mesenchymal Stem Cells in Postmenopausal Osteoporosis

(2016) Li You et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Subchondral and epiphyseal bone remodeling following surgical transection and noninvasive rupture of the anterior cruciate ligament as models of post-traumatic osteoarthritis

(2016) T. Maerz et al.   OSTEOARTHRITIS AND CARTILAGE

miR-582-5P induces colorectal cancer cell proliferation by targeting adenomatous polyposis coli

(2016) Zhenbo Shu et al.   World Journal of Surgical Oncology

MiR-15a-5p regulates viability and matrix degradation of human osteoarthritis chondrocytes via targeting VEGFA

(2016) Hongwei Chen et al.   BioScience Trends

The Prevalence of Symptomatic Knee Osteoarthritis in China: Results From the China Health and Retirement Longitudinal Study

(2016) Xu Tang et al.   Arthritis & Rheumatology

Attenuation of the Progression of Articular Cartilage Degeneration by Inhibition of TGF-β1 Signaling in a Mouse Model of Osteoarthritis

(2015) Rebecca Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Stem Cell Therapies in Clinical Trials: Progress and Challenges

(2015) Alan Trounson et al.   Cell Stem Cell

MicroRNA-153 suppresses the osteogenic differentiation of human mesenchymal stem cells by targeting bone morphogenetic protein receptor type II

(2015) YUJING CAO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Cartilage degeneration and excessive subchondral bone formation in spontaneous osteoarthritis involves altered TGF-β signaling

(2015) Weiwei Zhao et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Osteoarthritis

(2015) S Glyn-Jones et al.   LANCET

Intermittent applied mechanical loading induces subchondral bone thickening that may be intensified locally by contiguous articular cartilage lesions

(2015) B. Poulet et al.   OSTEOARTHRITIS AND CARTILAGE

miR-582-5p inhibits proliferation of hepatocellular carcinoma by targeting CDK1 and AKT3

(2015) Yi Zhang et al.   TUMOR BIOLOGY

MicroRNA-146a Regulates Human Foetal Femur Derived Skeletal Stem Cell Differentiation by Down-Regulating SMAD2 and SMAD3

(2014) Kelvin S. C. Cheung et al.   PLoS One

Articular cartilage-derived cells hold a strong osteogenic differentiation potential in comparison to mesenchymal stem cells in vitro

(2013) Achim Salamon et al.   EXPERIMENTAL CELL RESEARCH

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

(2013) Gehua Zhen et al.   NATURE MEDICINE

miR-346 Regulates Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells by Targeting the Wnt/β-Catenin Pathway

(2013) Qing Wang et al.   PLoS One

miR-582-5p Is Upregulated in Patients with Active Tuberculosis and Inhibits Apoptosis of Monocytes by Targeting FOXO1

(2013) Yanhua Liu et al.   PLoS One

Insights on Biology and Pathology of HIF-1α/-2α, TGFβ/BMP, Wnt/β-Catenin, and NF-κB Pathways in Osteoarthritis

(2012) Longhuo Wu et al.   CURRENT PHARMACEUTICAL DESIGN

New molecular targets for the treatment of osteoarthritis

(2010) Maria José Alcaraz et al.   BIOCHEMICAL PHARMACOLOGY

The basic science of the subchondral bone

(2010) Henning Madry et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

The bone–cartilage unit in osteoarthritis

(2010) Rik J. Lories et al.   Nature Reviews Rheumatology

Smad Signaling Determines Chondrogenic Differentiation of Bone-Marrow-Derived Mesenchymal Stem Cells: Inhibition of Smad1/5/8P Prevents Terminal Differentiation and Calcification

(2010) Catharine A. Hellingman et al.   TISSUE ENGINEERING PART A

Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss: the MOST Study. A longitudinal multicentre study of knee osteoarthritis

(2008) F W Roemer et al.   ANNALS OF THE RHEUMATIC DISEASES