Inference of causal metabolite networks in the presence of invalid instrumental variables with GWAS summary data

Causal Inference in Transcriptome-Wide Association Studies with Invalid Instruments and GWAS Summary Data

(2023) Haoran Xue et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Lipid metabolism and Alzheimer's disease: clinical evidence, mechanistic link and therapeutic promise

(2022) Fei Yin   FEBS Journal

Robust inference of bi-directional causal relationships in presence of correlated pleiotropy with GWAS summary data

(2022) Haoran Xue et al.   PLoS Genetics

Networks and Graphs Discovery in Metabolomics Data Analysis and Interpretation

(2022) Adam Amara et al.   Frontiers in Molecular Biosciences

Fine-mapping from summary data with the “Sum of Single Effects” model

(2022) Yuxin Zou et al.   PLoS Genetics

The Therapeutic Potential of Carnosine/Anserine Supplementation against Cognitive Decline: A Systematic Review with Meta-Analysis

(2021) Giuseppe Caruso et al.   Biomedicines

β-Lactolin, a Whey-Derived Lacto-Tetrapeptide, Prevents Alzheimer’s Disease Pathologies and Cognitive Decline

(2020) Yasuhisa Ano et al.   JOURNAL OF ALZHEIMERS DISEASE

A simple new approach to variable selection in regression, with application to genetic fine mapping

(2020) Gao Wang et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Penalized regression and model selection methods for polygenic scores on summary statistics

(2020) Jack Pattee et al.   PLoS Computational Biology

Implicating causal brain imaging endophenotypes in Alzheimer’s disease using multivariable IWAS and GWAS summary data

(2020) Katherine A. Knutson et al.   NEUROIMAGE

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases

(2019) Serena Sanna et al.   NATURE GENETICS

Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics

(2019) Azam Yazdani et al.   BMC GENOMICS

On the Use of the Lasso for Instrumental Variables Estimation with Some Invalid Instruments

(2018) Frank Windmeijer et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Polygenic scores via penalized regression on summary statistics

(2017) Timothy Shin Heng Mak et al.   GENETIC EPIDEMIOLOGY

Automated pathway and reaction prediction facilitates in silico identification of unknown metabolites in human cohort studies

(2017) Jan D. Quell et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

A new statistical framework for genetic pleiotropic analysis of high dimensional phenotype data

(2016) Panpan Wang et al.   BMC GENOMICS

Instrumental Variables Estimation With Some Invalid Instruments and its Application to Mendelian Randomization

(2016) Hyunseung Kang et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels

(2016) Azam Yazdani et al.   Metabolomics

Integrative approaches for large-scale transcriptome-wide association studies

(2016) Alexander Gusev et al.   NATURE GENETICS

Characterizing Blood Metabolomics Profiles Associated with Self-Reported Food Intakes in Female Twins

(2016) Tess Pallister et al.   PLoS One

Maximizing the Power of Principal-Component Analysis of Correlated Phenotypes in Genome-wide Association Studies

(2014) Hugues Aschard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An atlas of genetic influences on human blood metabolites

(2014) So-Youn Shin et al.   NATURE GENETICS

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

STATISTICAL METHODS FOR THE ANALYSIS OF HIGH-THROUGHPUT METABOLOMICS DATA

(2013) Jörg Bartel et al.   Computational and Structural Biotechnology Journal

Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease

(2012) Rongqing Chen et al.   Cell Reports

Mining the Unknown: A Systems Approach to Metabolite Identification Combining Genetic and Metabolic Information

(2012) Jan Krumsiek et al.   PLoS Genetics

Linking lipids to Alzheimer's disease: cholesterol and beyond

(2011) Gilbert Di Paolo et al.   NATURE REVIEWS NEUROSCIENCE

Gene Network Inference via Structural Equation Modeling in Genetical Genomics Experiments

(2008) B. Liu et al.   GENETICS

Xenobiotic metabolizing enzymes in the central nervous system: Contribution of cytochrome P450 enzymes in normal and pathological human brain

(2007) Fabien Dutheil et al.   BIOCHIMIE