Behavior of platinum(iv) complexes in models of tumor hypoxia: cytotoxicity, compound distribution and accumulation

Three-dimensional and co-culture models for preclinical evaluation of metal-based anticancer drugs

(2015) Ekaterina Schreiber-Brynzak et al.   INVESTIGATIONAL NEW DRUGS

Tumor microenvironment in focus: LA-ICP-MS bioimaging of a preclinical tumor model upon treatment with platinum(iv)-based anticancer agents

(2015) Sarah Theiner et al.   Metallomics

Influence of reducing agents on the cytotoxic activity of platinum(iv) complexes: induction of G2/M arrest, apoptosis and oxidative stress in A2780 and cisplatin resistant A2780cis cell lines

(2015) Verena Pichler et al.   Metallomics

Changes in Protein Expression in Two Cholangiocarcinoma Cell Lines Undergoing Formation of Multicellular Tumor Spheroids In Vitro

(2015) Carlo Mischiati et al.   PLoS One

Quantitative measurement of redox potential in hypoxic cells using SERS nanosensors

(2014) Jing Jiang et al.   Nanoscale

Bulky N(,N)-(Di)alkylethane-1,2-diamineplatinum(II) Compounds as Precursors for Generating Unsymmetrically Substituted Platinum(IV) Complexes

(2013) Verena Pichler et al.   INORGANIC CHEMISTRY

Redox activation of metal-based prodrugs as a strategy for drug delivery

(2012) Nora Graf et al.   ADVANCED DRUG DELIVERY REVIEWS

DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination

(2012) Christopher Korch et al.   GYNECOLOGIC ONCOLOGY

Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy

(2012) Geeta Mehta et al.   JOURNAL OF CONTROLLED RELEASE

What do we know about the reduction of Pt(IV) pro-drugs?

(2012) Ezequiel Wexselblatt et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Phase I study of the effects of renal impairment on the pharmacokinetics and safety of satraplatin in patients with refractory solid tumors

(2011) M. D. Galsky et al.   ANNALS OF ONCOLOGY

Retrospective Analysis of Satraplatin in Patients with Metastatic Urothelial Cancer Refractory to Standard Platinum-Based Chemotherapy

(2011) Matthew D. Galsky et al.   Clinical Genitourinary Cancer

Clinical and pharmacokinetic evaluation of satraplatin

(2011) Gury Doshi et al.   Expert Opinion on Drug Metabolism & Toxicology

Iolite: Freeware for the visualisation and processing of mass spectrometric data

(2011) Chad Paton et al.   JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY

Activation of the cisplatin and transplatin complexes in solution with constant pH and concentration of chloride anions; quantum chemical study

(2011) Tomáš Zimmermann et al.   JOURNAL OF MOLECULAR MODELING

Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

(2010) Johanna Chiche et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Results of a phase II open-label, nonrandomized trial of oral satraplatin in patients with metastatic breast cancer

(2009) John W. Smith et al.   BREAST CANCER RESEARCH AND TREATMENT

Current Status and Future Prospects for Satraplatin, an Oral Platinum Analogue

(2008) H. Choy et al.   CLINICAL CANCER RESEARCH