Influence of reducing agents on the cytotoxic activity of platinum(iv) complexes: induction of G2/M arrest, apoptosis and oxidative stress in A2780 and cisplatin resistant A2780cis cell lines

Metal-based anticancer chemotherapeutic agents

(2014) Nafees Muhammad et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

l-Selenomethionine reduces platinum(iv) anticancer model compounds at strikingly faster rates thanl-methionine

(2014) Shuying Huo et al.   DALTON TRANSACTIONS

A New Entry to Asymmetric Platinum(IV) Complexes via Oxidative Chlorination

(2014) Mauro Ravera et al.   INORGANIC CHEMISTRY

Synthetic Methods for the Preparation of Platinum Anticancer Complexes

(2013) Justin J. Wilson et al.   CHEMICAL REVIEWS

Bulky N(,N)-(Di)alkylethane-1,2-diamineplatinum(II) Compounds as Precursors for Generating Unsymmetrically Substituted Platinum(IV) Complexes

(2013) Verena Pichler et al.   INORGANIC CHEMISTRY

NMR Investigation of the Spontaneous Thermal- and/or Photoinduced Reduction of trans Dihydroxido Pt(IV) Derivatives

(2013) Emanuele Petruzzella et al.   INORGANIC CHEMISTRY

Influence of Equatorial and Axial Carboxylato Ligands on the Kinetic Inertness of Platinum(IV) Complexes in the Presence of Ascorbate and Cysteine and within DLD-1 Cancer Cells

(2013) Catherine K. J. Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Platinum(IV) Complexes Featuring Axial (1, 4-13C2)Succinato Ligands - Synthesis, Characterization, and Preliminary ­Investigations in Cancer Cell Lysates

(2013) Jelena Banfic et al.   ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE

Caspase Functions in Cell Death and Disease

(2013) D. R. McIlwain et al.   Cold Spring Harbor Perspectives in Biology

Redox activation of metal-based prodrugs as a strategy for drug delivery

(2012) Nora Graf et al.   ADVANCED DRUG DELIVERY REVIEWS

Novel tetracarboxylatoplatinum(iv) complexes as carboplatin prodrugs

(2012) Hristo P. Varbanov et al.   DALTON TRANSACTIONS

Cellular accumulation and DNA interaction studies of cytotoxic trans-platinum anticancer compounds

(2012) Caroline Bartel et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Unsymmetric Mono- and Dinuclear Platinum(IV) Complexes Featuring an Ethylene Glycol Moiety: Synthesis, Characterization, and Biological Activity

(2012) Verena Pichler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tuning the Activity of Platinum(IV) Anticancer Complexes through Asymmetric Acylation

(2012) Chee Fei Chin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Platinum(ii/iv) complexes containing ethylenediamine-N,N′-di-2/3-propionate ester ligands induced caspase-dependent apoptosis in cisplatin-resistant colon cancer cells

(2012) Goran N. Kaluđerović et al.   Metallomics

Platinum-(IV)-derivative satraplatin induced G2/M cell cycle perturbation via p53-p21waf1/cip1-independent pathway in human colorectal cancer cells

(2011) Murugan Kalimutho et al.   ACTA PHARMACOLOGICA SINICA

Anticancer Activity of Metal Complexes: Involvement of Redox Processes

(2011) Ute Jungwirth et al.   ANTIOXIDANTS & REDOX SIGNALING

Pt(iv) analogs of oxaliplatin that do not follow the expected correlation between electrochemical reduction potential and rate of reduction by ascorbate

(2011) Jenny Z. Zhang et al.   CHEMICAL COMMUNICATIONS

The status of platinum anticancer drugs in the clinic and in clinical trials

(2010) Nial J. Wheate et al.   DALTON TRANSACTIONS

Molecular and statistical modeling of reduction peak potential and lipophilicity of platinum(IV) complexes

(2010) James A. Platts et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes

(2010) Michael R. Reithofer et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry

(2010) Maxim Isabelle et al.   Proteome Science

Synthesis, characterization, in vitro antitumoral investigations and interaction with plasmid pBR322 DNA of R2eddp-platinum(iv) complexes (R = Et, n-Pr)

(2009) Goran N. Kaluđerović et al.   DALTON TRANSACTIONS

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cells

(2008) Alexander E. Egger et al.   JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY