Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington’s disease peripheral blood samples
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington’s disease peripheral blood samples
Authors
Keywords
Metabolomics, Gene expression, Biomarkers, Disease progression, Neurodegenerative, Integrated analysis
Journal
Metabolomics
Volume 12, Issue 8, Pages -
Publisher
Springer Nature
Online
2016-07-27
DOI
10.1007/s11306-016-1084-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Deprivation of Folate and B12 Increases Neurodegeneration Beyond that Accompanying Deprivation of Either Vitamin Alone
- (2017) Lydia Kifle et al. JOURNAL OF ALZHEIMERS DISEASE
- Disruption of immune cell function by mutant huntingtin in Huntington's disease pathogenesis
- (2016) Ralph Andre et al. CURRENT OPINION IN PHARMACOLOGY
- Altered levels of acylcarnitines, phosphatidylcholines, and sphingomyelins in peritoneal fluid from ovarian endometriosis patients
- (2016) Katja Vouk et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms
- (2016) Idil Yet et al. PLoS One
- Huntington’s disease biomarker progression profile identified by transcriptome sequencing in peripheral blood
- (2015) Anastasios Mastrokolias et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis
- (2015) Hiroshi Tsugawa et al. NATURE METHODS
- MetaboAnalyst 3.0—making metabolomics more meaningful
- (2015) Jianguo Xia et al. NUCLEIC ACIDS RESEARCH
- WikiPathways: capturing the full diversity of pathway knowledge
- (2015) Martina Kutmon et al. NUCLEIC ACIDS RESEARCH
- Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels
- (2015) Harmen H. M. Draisma et al. Nature Communications
- A unique array of neuroprotective effects of pyruvate in neuropathology
- (2015) Yuri Zilberter et al. Frontiers in Neuroscience
- Homocysteine and DNA methylation: A review of animal and human literature
- (2014) Pooja R. Mandaviya et al. MOLECULAR GENETICS AND METABOLISM
- Huntington disease: natural history, biomarkers and prospects for therapeutics
- (2014) Christopher A. Ross et al. Nature Reviews Neurology
- B vitamin polymorphisms and behavior: Evidence of associations with neurodevelopment, depression, schizophrenia, bipolar disorder and cognitive decline
- (2014) E. Siobhan Mitchell et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- voom: precision weights unlock linear model analysis tools for RNA-seq read counts
- (2014) Charity W Law et al. GENOME BIOLOGY
- Skeletal muscle pathology in Huntington's disease
- (2014) Daniel Zielonka et al. Frontiers in Physiology
- Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles
- (2013) Harish Dharuri et al. BMC GENOMICS
- PGC-1α, mitochondrial dysfunction, and Huntington's disease
- (2013) Ashu Johri et al. FREE RADICAL BIOLOGY AND MEDICINE
- Metabolic network as a progression biomarker of premanifest Huntington’s disease
- (2013) Chris C. Tang et al. JOURNAL OF CLINICAL INVESTIGATION
- Alterations in cerebrospinal fluid glycerophospholipids and phospholipase A2activity in Alzheimer's disease
- (2013) Alfred N. Fonteh et al. JOURNAL OF LIPID RESEARCH
- Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data
- (2013) Sarah J Tabrizi et al. LANCET NEUROLOGY
- Biological functions of sphingomyelins
- (2013) J. Peter Slotte PROGRESS IN LIPID RESEARCH
- A failure in energy metabolism and antioxidant uptake precede symptoms of Huntington’s disease in mice
- (2013) Aníbal I. Acuña et al. Nature Communications
- On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies
- (2012) Ann-Kristin Petersen et al. BMC BIOINFORMATICS
- Increased sensitivity of next generation sequencing-based expression profiling after globin reduction in human blood RNA
- (2012) Anastasios Mastrokolias et al. BMC GENOMICS
- Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression
- (2012) Dongbo Yu et al. CELL
- Power of metabolomics in diagnosis and biomarker discovery of hepatocellular carcinoma
- (2012) Xijun Wang et al. HEPATOLOGY
- Serum carnitine levels and levocarnitine supplementation in institutionalized Huntington’s disease patients
- (2012) Miroslav Cuturic et al. NEUROLOGICAL SCIENCES
- The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013
- (2012) Janna Hastings et al. NUCLEIC ACIDS RESEARCH
- Validation of Plasma Branched Chain Amino Acids as Biomarkers in Huntington Disease
- (2011) Fanny Mochel et al. ARCHIVES OF NEUROLOGY
- Energy deficit in Huntington disease: why it matters
- (2011) Fanny Mochel et al. JOURNAL OF CLINICAL INVESTIGATION
- Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics
- (2011) Werner Römisch-Margl et al. Metabolomics
- KEGG for integration and interpretation of large-scale molecular data sets
- (2011) M. Kanehisa et al. NUCLEIC ACIDS RESEARCH
- Targeting Several CAG Expansion Diseases by a Single Antisense Oligonucleotide
- (2011) Melvin M. Evers et al. PLoS One
- Differences between Human Plasma and Serum Metabolite Profiles
- (2011) Zhonghao Yu et al. PLoS One
- Emerging roles for cholesterol in Huntington's disease
- (2011) Marta Valenza et al. TRENDS IN NEUROSCIENCES
- Phosphatidylcholine Biosynthesis during Neuronal Differentiation and Its Role in Cell Fate Determination
- (2010) Hebe Marcucci et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Growth hormone response to arginine test differentiates between two subgroups of Huntington's disease patients
- (2010) E. Salvatore et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders
- (2010) Giles E. Hardingham et al. NATURE REVIEWS NEUROSCIENCE
- Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting
- (2010) Karsten Suhre et al. PLoS One
- Sterols and sphingolipids: Dynamic duo or partners in crime?
- (2010) Sonia Gulati et al. PROGRESS IN LIPID RESEARCH
- Huntington's disease: The current state of research with peripheral tissues
- (2009) Jenny Sassone et al. EXPERIMENTAL NEUROLOGY
- Homocysteine, folate and vitamin B12in neuropsychiatric diseases: review and treatment recommendations
- (2009) Olaf Stanger et al. Expert Review of Neurotherapeutics
- A genome-wide perspective of genetic variation in human metabolism
- (2009) Thomas Illig et al. NATURE GENETICS
- Metabonomic Characterization of the 3-Nitropropionic Acid Rat Model of Huntington’s Disease
- (2009) T. M. Tsang et al. NEUROCHEMICAL RESEARCH
- KEGG for representation and analysis of molecular networks involving diseases and drugs
- (2009) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- Glucose Homeostasis in Huntington Disease
- (2008) Nebojša M. Lalić et al. ARCHIVES OF NEUROLOGY
- Enhanced autophagy and mitochondrial aberrations in murine GM1-gangliosidosis
- (2008) Ayumi Takamura et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dysregulation of Gene Expression in Primary Neuron Models of Huntington's Disease Shows That Polyglutamine-Related Effects on the Striatal Transcriptome May Not Be Dependent on Brain Circuitry
- (2008) H. Runne et al. JOURNAL OF NEUROSCIENCE
- Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum
- (2008) Christian Gieger et al. PLoS Genetics
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started