NMR analysis of the CSF and plasma metabolome of rigorously matched amyotrophic lateral sclerosis, Parkinson’s disease and control subjects

Multi-platform mass spectrometry analysis of the CSF and plasma metabolomes of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects

(2016) Anna Wuolikainen et al.   Molecular BioSystems

The human saliva metabolome

(2015) Zerihun T. Dame et al.   Metabolomics

Constrained randomization and multivariate effect projections improve information extraction and biomarker pattern discovery in metabolomics studies involving dependent samples

(2015) Pär Jonsson et al.   Metabolomics

Compromised autophagy and neurodegenerative diseases

(2015) Fiona M. Menzies et al.   NATURE REVIEWS NEUROSCIENCE

NMR metabonomics of cerebrospinal fluid distinguishes between Parkinson’s disease and controls

(2015) Anders Öhman et al.   NEUROSCIENCE LETTERS

Differential regulation of mTORC1 by leucine and glutamine

(2015) J. L. Jewell et al.   SCIENCE

The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis

(2015) Elizabeth Gray et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

(2014) Staffan Holmqvist et al.   ACTA NEUROPATHOLOGICA

Mannose metabolism: More than meets the eye

(2014) Vandana Sharma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Requirement for lysosomal localization of mTOR for its activation differs between leucine and other amino acids

(2014) Julien Averous et al.   CELLULAR SIGNALLING

Metabolomics of Human Brain Aging and Age-Related Neurodegenerative Diseases

(2014) Mariona Jové et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Plasma metabolomic biomarker panel to distinguish patients with amyotrophic lateral sclerosis from disease mimics

(2014) Kay A. Lawton et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Ketogenic Diet in Neuromuscular and Neurodegenerative Diseases

(2014) Antonio Paoli et al.   Biomed Research International

NMR identification of endogenous metabolites interacting with fatted and non-fatted human serum albumin in blood plasma: Fatty acids influence the HSA–metabolite interaction

(2013) Marc Jupin et al.   JOURNAL OF MAGNETIC RESONANCE

NMR metabolomics profiling of blood plasma mimics shows that medium- and long-chain fatty acids differently release metabolites from human serum albumin

(2013) M. Jupin et al.   JOURNAL OF MAGNETIC RESONANCE

Metabolomics in Cerebrospinal Fluid of Patients with Amyotrophic Lateral Sclerosis: An Untargeted Approach via High-Resolution Mass Spectrometry

(2013) Hélène Blasco et al.   JOURNAL OF PROTEOME RESEARCH

3-hydroxykynurenine and other Parkinson's disease biomarkers discovered by metabolomic analysis

(2013) Peter A. LeWitt et al.   MOVEMENT DISORDERS

The Human Urine Metabolome

(2013) Souhaila Bouatra et al.   PLoS One

Are professional soccer players at higher risk for ALS?

(2013) Ettore Beghi   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Large neutral amino acids: dietary effects on brain neurochemistry and function

(2012) John D. Fernstrom   AMINO ACIDS

Roadmap and standard operating procedures for biobanking and discovery of neurochemical markers in ALS

(2012) Markus Otto et al.   Amyotrophic Lateral Sclerosis

NMR and pattern recognition methods in metabolomics: From data acquisition to biomarker discovery: A review

(2012) Agnieszka Smolinska et al.   ANALYTICA CHIMICA ACTA

Simultaneous analysis of plasma and CSF by NMR and hierarchical models fusion

(2012) Agnieszka Smolinska et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

(2012) J. Xia et al.   NUCLEIC ACIDS RESEARCH

HMDB 3.0—The Human Metabolome Database in 2013

(2012) David S. Wishart et al.   NUCLEIC ACIDS RESEARCH

Multi-platform characterization of the human cerebrospinal fluid metabolome: a comprehensive and quantitative update

(2012) Rupasri Mandal et al.   Genome Medicine

Biochemical alterations associated with ALS

(2011) Kay A. Lawton et al.   Amyotrophic Lateral Sclerosis

The Seeds of Neurodegeneration: Prion-like Spreading in ALS

(2011) Magdalini Polymenidou et al.   CELL

EFNS guidelines on the Clinical Management of Amyotrophic Lateral Sclerosis (MALS) - revised report of an EFNS task force

(2011) et al.   EUROPEAN JOURNAL OF NEUROLOGY

Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk

(2011) J. V. Li et al.   GUT

Recent and potential developments of biofluid analyses in metabolomics

(2011) Aihua Zhang et al.   Journal of Proteomics

Amyotrophic lateral sclerosis

(2011) Matthew C Kiernan et al.   LANCET

The Human Serum Metabolome

(2011) Nikolaos Psychogios et al.   PLoS One

Disease-Related Changes in the Cerebrospinal Fluid Metabolome in Amyotrophic Lateral Sclerosis Detected by GC/TOFMS

(2011) Anna Wuolikainen et al.   PLoS One

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

(2010) Warwick B. Dunn et al.   CHEMICAL SOCIETY REVIEWS

Metabolomic analysis of serum by (1) H NMR spectroscopy in amyotrophic lateral sclerosis

(2010) Alok Kumar et al.   CLINICA CHIMICA ACTA

Stronger is not always better: Could a bodybuilding dietary supplement lead to ALS?

(2010) Marin Manuel et al.   EXPERIMENTAL NEUROLOGY

Quantitative Proteomics and Metabolomics Analysis of Normal Human Cerebrospinal Fluid Samples*

(2010) Marcel P. Stoop et al.   MOLECULAR & CELLULAR PROTEOMICS

Global metabolic profiling procedures for urine using UPLC–MS

(2010) Elizabeth J Want et al.   Nature Protocols

Decrease in Asymmetrical Dimethylarginine, an Endogenous Nitric Oxide Synthase Inhibitor, in Cerebrospinal Fluid during Elderly Aging and in Patients with Sporadic Form of Amyotrophic Lateral Sclerosis

(2010) Chiaki Isobe et al.   NEUROSIGNALS

α-Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population

(2010) Walter E. Gall et al.   PLoS One

Novel Antibodies Reveal Inclusions Containing Non-Native SOD1 in Sporadic ALS Patients

(2010) Karin Forsberg et al.   PLoS One

1H-NMR-Based Metabolomic Profiling of CSF in Early Amyotrophic Lateral Sclerosis

(2010) Hélène Blasco et al.   PLoS One

The influence of EDTA and citrate anticoagulant addition to human plasma on information recovery from NMR-based metabolic profiling studies

(2009) Richard H. Barton et al.   Molecular BioSystems

Metabolomics tools for identifying biomarkers for neuropsychiatric diseases

(2009) Marlon P. Quinones et al.   NEUROBIOLOGY OF DISEASE

CV-ANOVA for significance testing of PLS and OPLS® models

(2008) Lennart Eriksson et al.   JOURNAL OF CHEMOMETRICS

The human cerebrospinal fluid metabolome

(2008) David S. Wishart et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The blood-cerebrospinal fluid barrier is a major pathway of cerebral creatinine clearance: involvement of transporter-mediated process

(2008) Masanori Tachikawa et al.   JOURNAL OF NEUROCHEMISTRY

Systems biology: Metabonomics

(2008) Jeremy K. Nicholson et al.   NATURE