Response of lymphatic endothelial cells to combined spatial and temporal variations in fluid flow

Lymphatic endothelial cell calcium pulses are sensitive to spatial gradients in wall shear stress

(2019) Vinay N. Surya et al.   MOLECULAR BIOLOGY OF THE CELL

Transcriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation

(2018) Mingming Zhao et al.   PLOS BIOLOGY

Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation

(2018) Keiko Nonomura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Laminar flow downregulates Notch activity to promote lymphatic sprouting

(2017) Dongwon Choi et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves

(2016) Boksik Cha et al.   GENES & DEVELOPMENT

Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation

(2016) Anees Fatima et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of dynamic shear and transmural pressure on wall shear stress sensitivity in collecting lymphatic vessels

(2015) Jeffrey A. Kornuta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Combining Foxc2 and Connexin37 deletions in mice leads to severe defects in lymphatic vascular growth and remodeling

(2015) John D. Kanady et al.   DEVELOPMENTAL BIOLOGY

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature

(2015) Amélie Sabine et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymph flow regulates collecting lymphatic vessel maturation in vivo

(2015) Daniel T. Sweet et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch signaling functions in lymphatic valve formation

(2014) A. Murtomaki et al.   DEVELOPMENT

Lymph Transport in Rat Mesenteric Lymphatics Experiencing Edemagenic Stress

(2014) Elaheh Rahbar et al.   MICROCIRCULATION

Lymphatic collecting vessel maturation and valve morphogenesis

(2014) Daniel Vittet   MICROVASCULAR RESEARCH

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequency decoding of calcium oscillations

(2013) Erik Smedler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mechanical forces in lymphatic vascular development and disease

(2013) Lara Planas-Paz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis

(2013) Florence Tatin et al.   DEVELOPMENTAL CELL

EMILIN1/α9β1 Integrin Interaction Is Crucial in Lymphatic Valve Formation and Maintenance

(2013) Carla Danussi et al.   MOLECULAR AND CELLULAR BIOLOGY

Flow control in our vessels: vascular valves make sure there is no way back

(2012) Eleni Bazigou et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation

(2012) Amélie Sabine et al.   DEVELOPMENTAL CELL

Low-cost microcontroller platform for studying lymphatic biomechanics in vitro

(2012) Jeffrey A. Kornuta et al.   JOURNAL OF BIOMECHANICS

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice

(2012) Philip E. Lapinski et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamic Response Diversity of NFAT Isoforms in Individual Living Cells

(2012) Nissan Yissachar et al.   MOLECULAR CELL

Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels

(2012) Yoojin Shin et al.   Nature Protocols

Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves

(2011) R. S. Srinivasan et al.   GENES & DEVELOPMENT

The lymphatic vasculature in disease

(2011) Kari Alitalo   NATURE MEDICINE

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Human thoracic duct in vitro: diameter-tension properties, spontaneous and evoked contractile activity

(2010) Niklas Telinius et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Integrin-α9 Is Required for Fibronectin Matrix Assembly during Lymphatic Valve Morphogenesis

(2009) Eleni Bazigou et al.   DEVELOPMENTAL CELL

Transport-mediated angiogenesis in 3D epithelial coculture

(2009) Ryo Sudo et al.   FASEB JOURNAL

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

(2009) Camilla Norrmén et al.   JOURNAL OF CELL BIOLOGY

Contractile Physiology of Lymphatics

(2009) David C. Zawieja   Lymphatic Research and Biology

Diagnosis and Management of Lymphatic Vascular Disease

(2008) Stanley G. Rockson   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging

(2008) Vernella Vickerman et al.   LAB ON A CHIP