Alveolar epithelial cell growth hormone releasing hormone receptor in alveolar epithelial inflammation

Growth hormone releasing hormone signaling promotes Th17 cell differentiation and autoimmune inflammation

(2023) Lin Du et al.   Nature Communications

Basal Cell-derived WNT7A Promotes Fibrogenesis at the Fibrotic Niche in Idiopathic Pulmonary Fibrosis

(2022) Guanling Huang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Airway basal cells show a dedifferentiated KRT17highPhenotype and promote fibrosis in idiopathic pulmonary fibrosis

(2022) Benedikt Jaeger et al.   Nature Communications

iPSC-derived Alveolar Type II (iAEC2) Heterogeneity: Revealed by SFTPC Expression

(2021) Hongmei Mou   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mesenchymal growth hormone receptor deficiency leads to failure of alveolar progenitor cell function and severe pulmonary fibrosis

(2021) Ting Xie et al.   Science Advances

Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells

(2021) Jaymin J. Kathiriya et al.   NATURE CELL BIOLOGY

Synthesis of potent antagonists of receptors for growth hormone-releasing hormone with antitumor and anti-inflammatory activity

(2021) Renzhi Cai et al.   PEPTIDES

Signaling mechanisms of growth hormone-releasing hormone receptor in LPS-induced acute ocular inflammation

(2020) Wei Cheng Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recapitulating idiopathic pulmonary fibrosis related alveolar epithelial dysfunction in a human iPSC‐derived air‐liquid interface model

(2020) Eva Schruf et al.   FASEB JOURNAL

Alveolar wars: The rise of in vitro models to understand human lung alveolar maintenance, regeneration, and disease

(2020) Kelly V. Evans et al.   Stem Cells Translational Medicine

Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis

(2020) Yoshihiko Kobayashi et al.   NATURE CELL BIOLOGY

Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

(2020) Arun C. Habermann et al.   Science Advances

Structural basis for activation of the growth hormone-releasing hormone receptor

(2020) Fulai Zhou et al.   Nature Communications

Growth Hormone-Releasing Hormone in Lung Physiology and Pulmonary Disease

(2020) Chongxu Zhang et al.   Cells

Growth Hormone-Releasing Hormone Receptor Antagonist Modulates Lung Inflammation and Fibrosis due to Bleomycin

(2019) Chongxu Zhang et al.   LUNG

Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells

(2019) Anjali Jacob et al.   Nature Protocols

Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor

(2018) William J. Zacharias et al.   NATURE

Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis

(2018) Chiharu Ota et al.   Scientific Reports

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

(2018) Paul A Reyfman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Synthesis and structure-activity studies on novel analogs of human growth hormone releasing hormone (GHRH) with enhanced inhibitory activities on tumor growth

(2017) Marta Zarandi et al.   PEPTIDES

Statistical Methods for Cardiovascular Researchers

(2016) Lem Moyé   CIRCULATION RESEARCH

Agonistic analogs of growth hormone releasing hormone (GHRH) promote wound healing by stimulating the proliferation and survival of human dermal fibroblasts through ERK and AKT pathways

(2016) Tengjiao Cui et al.   Oncotarget

Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus

(2012) Beata Kosmider et al.   RESPIRATORY RESEARCH

β-catenin signaling

(2011) Anna P. Lam et al.   CURRENT OPINION IN RHEUMATOLOGY

Blockade of the Wnt/β-Catenin Pathway Attenuates Bleomycin-Induced Pulmonary Fibrosis

(2011) Tae Hyung Kim et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of Wnt/ -catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

(2010) W. R. Henderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WNT1-inducible signaling protein–1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis

(2009) Melanie Königshoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Wnt and beyond Wnt: Multiple mechanisms control the transcriptional property of β-catenin

(2008) Tianru Jin et al.   CELLULAR SIGNALLING