Involvement of estrogen receptor activation in kaempferol-3-O-glucoside's protection against aging-related cognition impairment and microglial inflammation

Neuroprotective effect of astragalin via activating PI3K/Akt-mTOR-mediated autophagy on APP/PS1 mice

(2023) Cui-Zhu Yang et al.   Cell Death Discovery

Astragalin and Isoquercitrin Isolated from Aster scaber Suppress LPS-Induced Neuroinflammatory Responses in Microglia and Mice

(2022) Eun Hae Kim et al.   Foods

Astragalin attenuates AlCl3/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation

(2022) Yang Hu et al.   NEUROTOXICOLOGY

Non-Genomic Actions of Estrogens on the DNA Repair Pathways Are Associated With Chemotherapy Resistance in Breast Cancer

(2021) Javier E. Jiménez-Salazar et al.   Frontiers in Oncology

Lipopolysaccharide-induced depression is associated with estrogen receptor-α/SIRT1/NF-κB signaling pathway in old female mice

(2021) Xi Jiang et al.   NEUROCHEMISTRY INTERNATIONAL

Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction

(2021) Fuyuko Takata et al.   Frontiers in Cellular Neuroscience

Astragalin Exerted Antidepressant-like Action through SIRT1 Signaling Modulated NLRP3 Inflammasome Deactivation

(2020) Yue Tong et al.   ACS Chemical Neuroscience

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

(2020) Gill Livingston et al.   LANCET

Genistein Attenuates Acute Cerebral Ischemic Damage by Inhibiting the NLRP3 Inflammasome in Reproductively Senescent Mice

(2020) Shiquan Wang et al.   Frontiers in Aging Neuroscience

Comparison of the Protective Effects of Ginsenosides Rb1 and Rg1 on Improving Cognitive Deficits in SAMP8 Mice Based on Anti-Neuroinflammation Mechanism

(2020) Yujie Yang et al.   Frontiers in Pharmacology

Estrogen Attenuates Traumatic Brain Injury by Inhibiting the Activation of Microglia and Astrocyte-Mediated Neuroinflammatory Responses

(2020) Jin Wang et al.   MOLECULAR NEUROBIOLOGY

Activation of microglia and astrocytes: a roadway to neuroinflammation and Alzheimer’s disease

(2019) Darshpreet Kaur et al.   INFLAMMOPHARMACOLOGY

Anti-neuroinflammatory effect of Iresine celosia on lipopolysaccharide-stimulated microglial cells and mouse

(2019) Namkwon Kim et al.   BIOMEDICINE & PHARMACOTHERAPY

Vascular Cognitive Impairment and Dementia

(2019) Costantino Iadecola et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation

(2018) Joana Costa d’Avila et al.   Journal of Neuroinflammation

Administration of Dexmedetomidine inhibited NLRP3 inflammasome and microglial cell activities in hippocampus of traumatic brain injury rats

(2018) Bin Zheng et al.   BIOSCIENCE REPORTS

Novel Object Recognition Test for the Investigation of Learning and Memory in Mice

(2017) Lindsay M. Lueptow   Jove-Journal of Visualized Experiments

NLRP3 inflammasome activation mediates estrogen deficiency-induced depression- and anxiety-like behavior and hippocampal inflammation in mice

(2016) Yongjun Xu et al.   BRAIN BEHAVIOR AND IMMUNITY

The economic burden of dementia in China, 1990–2030: implications for health policy

(2016) Junfang Xu et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Estrogens, Neuroinflammation, and Neurodegeneration

(2016) Alessandro Villa et al.   ENDOCRINE REVIEWS

Neuroprotective effects of phytosterols and flavonoids from Cirsium setidens and Aster scaber in human brain neuroblastoma SK-N-SH cells

(2016) Mi Ja Chung et al.   LIFE SCIENCES

Inhibition of hippocampal estrogen synthesis by reactive microglia leads to down-regulation of synaptic protein expression

(2015) Siriporn Chamniansawat et al.   NEUROTOXICOLOGY

Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators

(2015) Mesut Muyan et al.   PLoS One

Anti-inflammatory effects of genistein via suppression of the toll-like receptor 4-mediated signaling pathway in lipopolysaccharide-stimulated BV2 microglia

(2014) Jin-Woo Jeong et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Estradiol and cognitive function: Past, present and future

(2014) Victoria N. Luine   HORMONES AND BEHAVIOR

Estrogen Receptors, the Hippocampus, and Memory

(2014) Linda A. Bean et al.   NEUROSCIENTIST

Flavonoids Induce the Synthesis and Secretion of Neurotrophic Factors in Cultured Rat Astrocytes: A Signaling Response Mediated by Estrogen Receptor

(2013) Sherry L. Xu et al.   Evidence-based Complementary and Alternative Medicine

Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer’s disease

(2013) B Parajuli et al.   Cell Death & Disease

Hippocampus in health and disease: An overview

(2012) Vikas Dhikav et al.   Annals of Indian Academy of Neurology

Estrogens, estrogen receptors, and female cognitive aging: The impact of timing

(2012) Jill M. Daniel   HORMONES AND BEHAVIOR

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Anti-Inflammatory Role of the Isoflavone Diadzein in Lipopolysaccharide-Stimulated Microglia: Implications for Parkinson’s Disease

(2012) Shankar J. Chinta et al.   NEUROTOXICITY RESEARCH

Testosterone Deficiency Accelerates Neuronal and Vascular Aging of SAMP8 Mice: Protective Role of eNOS and SIRT1

(2012) Hidetaka Ota et al.   PLoS One

Kaempferol acts through mitogen-activated protein kinases and protein kinase B/AKT to elicit protection in a model of neuroinflammation in BV2 microglial cells

(2011) SE Park et al.   BRITISH JOURNAL OF PHARMACOLOGY

Distinguishing Alzheimer’s disease from other major forms of dementia

(2011) Stella Karantzoulis et al.   Expert Review of Neurotherapeutics

Antiosteoporotic compounds from seeds of Cuscuta chinensis

(2011) Lijuan Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuroscientists as Cartographers: Mapping the Crossroads of Gonadal Hormones, Memory and Age Using Animal Models

(2010) Heather A. Bimonte-Nelson et al.   MOLECULES

Estrogen or Estrogen Receptor Agonist Inhibits Lipopolysaccharide Induced Microglial Activation and Death

(2010) Joshua A. Smith et al.   NEUROCHEMICAL RESEARCH

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY