Palmitic acid triggers cell apoptosis in RGC-5 retinal ganglion cells through the Akt/FoxO1 signaling pathway

Inhibition of SH2-domain-containing inositol 5-phosphatase (SHIP2) ameliorates palmitate induced-apoptosis through regulating Akt/FOXO1 pathway and ROS production in HepG2 cells

(2015) Sattar Gorgani-Firuzjaee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Forkhead box O1 mediates defects in palmitate-induced insulin granule exocytosis by downregulation of calcium/calmodulin-dependent serine protein kinase expression in INS-1 cells

(2015) Yao Wang et al.   DIABETOLOGIA

Nrf2 activators modulate oxidative stress responses and bioenergetic profiles of human retinal epithelial cells cultured in normal or high glucose conditions

(2015) Roberta Foresti et al.   PHARMACOLOGICAL RESEARCH

Lithium ions attenuate serum-deprivation-induced apoptosis in PC12 cells through regulation of the Akt/FoxO1 signaling pathways

(2015) Zhiwen Zeng et al.   PSYCHOPHARMACOLOGY

Cyclooxygenase-2-dependent oxidative stress mediates palmitate-induced impairment of endothelium-dependent relaxations in mouse arteries

(2014) Zhen Gao et al.   BIOCHEMICAL PHARMACOLOGY

Palmitic Acid-Induced Neuron Cell Cycle G2/M Arrest and Endoplasmic Reticular Stress through Protein Palmitoylation in SH-SY5Y Human Neuroblastoma Cells

(2014) Yung-Hsuan Hsiao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Palmitic acid-induced lipotoxicity and protection by (+)-catechin in rat cortical astrocytes

(2014) Kar-Lok Wong et al.   Pharmacological Reports

VEGF-A Is Necessary and Sufficient for Retinal Neuroprotection in Models of Experimental Glaucoma

(2013) Richard H. Foxton et al.   AMERICAN JOURNAL OF PATHOLOGY

Comparative Effectiveness of Treatments for Open-Angle Glaucoma: A Systematic Review for the U.S. Preventive Services Task Force

(2013) Michael V. Boland et al.   ANNALS OF INTERNAL MEDICINE

Saturated Free Fatty Acid Sodium Palmitate-Induced Lipoapoptosis by Targeting Glycogen Synthase Kinase-3β Activation in Human Liver Cells

(2013) Jie Cao et al.   DIGESTIVE DISEASES AND SCIENCES

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

(2013) Yi Lu et al.   NATURE GENETICS

Lithium normalizes amphetamine-induced changes in striatal FoxO1 phosphorylation and behaviors in rats

(2013) Wenhua Zheng et al.   NEUROREPORT

Protective Effects of Resveratrol in Experimental Retinal Detachment

(2013) Wei Huang et al.   PLoS One

The role of Akt/FoxO3a in the protective effect of venlafaxine against corticosterone-induced cell death in PC12 cells

(2013) Haitao Wang et al.   PSYCHOPHARMACOLOGY

Role of SIRT1-FoxO1 Signaling in Dietary Saturated Fat-Dependent Upregulation of Liver Adiponectin Receptor 2 in Ethanol-Administered Mice

(2011) Xiaomei Liang et al.   ANTIOXIDANTS & REDOX SIGNALING

Bimodal regulation of FoxO3 by AKT and 14-3-3

(2011) Melissa Dobson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Akt, FoxO and regulation of apoptosis

(2011) Xinbo Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Suppression of FoxO1/cell death-inducing DNA fragmentation factor α-like effector A (Cidea) axis protects mouse β-cells against palmitic acid-induced apoptosis

(2011) Naoki Omae et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Metformin reduces lipid accumulation in macrophages by inhibiting FOXO1-mediated transcription of fatty acid-binding protein 4

(2010) Jun Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Resveratrol inhibits the expression of SREBP1 in cell model of steatosis via Sirt1–FOXO1 signaling pathway

(2009) Guang-Li Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Palmitate Attenuates Insulin Signaling and Induces Endoplasmic Reticulum Stress and Apoptosis in Hypothalamic Neurons: Rescue of Resistance and Apoptosis through Adenosine 5′ Monophosphate-Activated Protein Kinase Activation

(2009) Christopher M. Mayer et al.   ENDOCRINOLOGY

Inhibition of Foxo1 Protects Pancreatic Islet  -Cells Against Fatty Acid and Endoplasmic Reticulum Stress-Induced Apoptosis

(2008) S. C. Martinez et al.   DIABETES

Glutamate Acting onN-Methyl-d-aspartate Receptors Attenuates Insulin-like Growth Factor-1 Receptor Tyrosine Phosphorylation and Its Survival Signaling Properties in Rat Hippocampal Neurons

(2008) Wen-Hua Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation and reversal of lipotoxicity in PC12 and rat cortical cells following exposure to palmitic acid

(2008) Frankis G. Almaguel et al.   JOURNAL OF NEUROSCIENCE RESEARCH