SB203580 reverses memory deficits and depression-like behavior induced by microinjection of Aβ1–42 into hippocampus of mice

Amyloid burden and incident depressive symptoms in cognitively normal older adults

(2016) Karra D. Harrington et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Hippocampal metabotropic glutamate receptor long-term depression in health and disease: focus on mitogen-activated protein kinase pathways

(2016) Thomas M. Sanderson et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial-generated ROS down regulates insulin signaling via activation of the p38MAPK stress response pathway

(2016) Rabab Al-Lahham et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Bacterial translocation affects intracellular neuroinflammatory pathways in a depression-like model in rats

(2016) David Martín-Hernández et al.   NEUROPHARMACOLOGY

Therapeutic strategies for Alzheimer's disease in clinical trials

(2016) Justyna Godyń et al.   Pharmacological Reports

Targeting Human Central Nervous System Protein Kinases: An Isoform Selective p38αMAPK Inhibitor That Attenuates Disease Progression in Alzheimer’s Disease Mouse Models

(2015) Saktimayee M. Roy et al.   ACS Chemical Neuroscience

Early inflammation-associated factors blunt sterol regulatory element-binding proteins-1-mediated lipogenesis in high-fat diet-fedAPPSWE/PSEN1dE9mouse model of Alzheimer's disease

(2015) Ying Tang et al.   JOURNAL OF NEUROCHEMISTRY

GSK3β-activation is a point of convergence for HIV-1 and opiate-mediated interactive neurotoxicity

(2015) Ruturaj R. Masvekar et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

CREB expression mediates amyloid β-induced basal BDNF downregulation

(2015) Elyse Rosa et al.   NEUROBIOLOGY OF AGING

Inhibition of Acid Sphingomyelinase by Antidepressants Counteracts Stress-Induced Activation of P38-Kinase in Major Depression

(2015) Heike Grassmé et al.   NEUROSIGNALS

Cyclic GMP–mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice

(2015) Lindsay M. Lueptow et al.   PSYCHOPHARMACOLOGY

Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus

(2015) Tahir Ali et al.   Scientific Reports

A new perspective on the role of the CREB family of transcription factors in memory consolidation via adult hippocampal neurogenesis

(2015) Sylvia Ortega-Martínez   Frontiers in Molecular Neuroscience

Hippocampal GSK3β as a Molecular Link Between Obesity and Depression

(2014) Ioannis K. Papazoglou et al.   MOLECULAR NEUROBIOLOGY

Involvement of P38MAPK activation by NMDA receptors and non-NMDA receptors in amyloid-β peptide-induced neuronal loss in rat hippocampal CA1 and CA3 subfields

(2014) Yan Xu et al.   NEUROSCIENCE RESEARCH

Systemic immune system alterations in early stages of Alzheimer's disease

(2013) Rongzhen Zhang et al.   JOURNAL OF NEUROIMMUNOLOGY

Enhancement of long-term depression by soluble amyloid β protein in rat hippocampus is mediated by metabotropic glutamate receptor and involves activation of p38MAPK, STEP and caspase-3

(2013) X. Chen et al.   NEUROSCIENCE

Pharmacogenomics of bipolar disorder

(2013) Giovanni Severino et al.   PHARMACOGENOMICS

GSK3β, CREB, and BDNF in peripheral blood of patients with Alzheimer's disease and depression

(2013) Jan Pláteník et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

PWZ-029, an inverse agonist selective for α5 GABAA receptors, improves object recognition, but not water-maze memory in normal and scopolamine-treated rats

(2012) Marija Milić et al.   BEHAVIOURAL BRAIN RESEARCH

RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects

(2012) Zhen-Zhen Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats

(2011) Chuang Wang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Adiponectin Stimulates Proliferation of Adult Hippocampal Neural Stem/Progenitor Cells through Activation of p38 Mitogen-activated Protein Kinase (p38MAPK)/Glycogen Synthase Kinase 3β (GSK-3β)/β-Catenin Signaling Cascade

(2011) Di Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic psychosocial stress enhances long-term depression in a subthreshold amyloid-beta rat model of Alzheimer’s disease

(2011) Trinh T. Tran et al.   JOURNAL OF NEUROCHEMISTRY

Phosphodiesterase-4D Knock-Out and RNA Interference-Mediated Knock-Down Enhance Memory and Increase Hippocampal Neurogenesis via Increased cAMP Signaling

(2011) Y.-F. Li et al.   JOURNAL OF NEUROSCIENCE

Selective modulation of the PKCɛ/p38MAP kinase signalling pathway for the antidepressant-like activity of amitriptyline

(2011) Nicoletta Galeotti et al.   NEUROPHARMACOLOGY

A -Mediated NMDA Receptor Endocytosis in Alzheimer's Disease Involves Ubiquitination of the Tyrosine Phosphatase STEP61

(2010) P. Kurup et al.   JOURNAL OF NEUROSCIENCE

Light and Electron Microscopy Study of Glycogen Synthase Kinase-3β in the Mouse Brain

(2010) Emma Perez-Costas et al.   PLoS One

Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model

(2010) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extrasynaptic NMDA Receptors Couple Preferentially to Excitotoxicity via Calpain-Mediated Cleavage of STEP

(2009) J. Xu et al.   JOURNAL OF NEUROSCIENCE

Antidepressant- and Anxiolytic-like Effects of the Phosphodiesterase-4 Inhibitor Rolipram on Behavior Depend on Cyclic AMP Response Element Binding Protein-Mediated Neurogenesis in the Hippocampus

(2009) Yun-Feng Li et al.   NEUROPSYCHOPHARMACOLOGY

GSK-3β Gene Expression in Human Postmortem Brain: Regional Distribution, Effects of Age and Suicide

(2008) Ghanshyam N. Pandey et al.   NEUROCHEMICAL RESEARCH

Activation of MKK6, an upstream activator of p38, in Alzheimer's disease

(2003) Xiongwei Zhu et al.   JOURNAL OF NEUROCHEMISTRY