Cyclic GMP–mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice

Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress

(2015) Ying Xu et al.   NEUROBIOLOGY OF AGING

PDE5 inhibition improves acquisition processes after learning via a central mechanism

(2015) S. Akkerman et al.   NEUROPHARMACOLOGY

Object memory enhancement by combining sub-efficacious doses of specific phosphodiesterase inhibitors

(2015) E. Bollen et al.   NEUROPHARMACOLOGY

Protective effects of phosphodiesterase 2 inhibitor on depression- and anxiety-like behaviors: Involvement of antioxidant and anti-apoptotic mechanisms

(2014) Lianshu Ding et al.   BEHAVIOURAL BRAIN RESEARCH

Mind the gap: Delayed manifestation of long-term object memory improvement by phosphodiesterase inhibitors

(2014) S. Akkerman et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Region-Specific Activation of CRTC1-CREB Signaling Mediates Long-Term Fear Memory

(2014) Mio Nonaka et al.   NEURON

Involvement of PKA, PKC, CAMK-II and MEK1/2 in the acute antidepressant-like effect of creatine in mice

(2014) Mauricio P. Cunha et al.   Pharmacological Reports

PDE5 Inhibition Improves Object Memory in Standard Housed Rats but Not in Rats Housed in an Enriched Environment: Implications for Memory Models?

(2014) Sven Akkerman et al.   PLoS One

Object recognition test in mice

(2013) Marianne Leger et al.   Nature Protocols

Retrieval and reconsolidation of object recognition memory are independent processes in the perirhinal cortex

(2013) I. Balderas et al.   NEUROSCIENCE

Object recognition testing: Rodent species, strains, housing conditions, and estrous cycle

(2012) Nick P. van Goethem et al.   BEHAVIOURAL BRAIN RESEARCH

Inhibition of phoshodiesterase type 2 or type 10 reverses object memory deficits induced by scopolamine or MK-801

(2012) Olga A.H. Reneerkens et al.   BEHAVIOURAL BRAIN RESEARCH

Interfering with Fos expression in rat perirhinal cortex impairs recognition memory

(2012) Ana Seoane et al.   HIPPOCAMPUS

Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway

(2012) Ying Xu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

What pharmacological interventions indicate concerning the role of the perirhinal cortex in recognition memory

(2012) M.W. Brown et al.   NEUROPSYCHOLOGIA

Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments

(2011) Thérèse Keravis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Selective phosphodiesterase inhibitors improve performance on the ED/ID cognitive task in rats

(2011) Joshua S. Rodefer et al.   NEUROPHARMACOLOGY

Immunohistochemical Localization of Phosphodiesterase 2A in Multiple Mammalian Species

(2009) Diane T. Stephenson et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Anxiolytic Effects of Phosphodiesterase-2 Inhibitors Associated with Increased cGMP Signaling

(2009) A. Masood et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Phosphodiesterase Inhibitors Enhance Object Memory Independent of Cerebral Blood Flow and Glucose Utilization in Rats

(2009) Kris Rutten et al.   NEUROPSYCHOPHARMACOLOGY

The effect of selective inhibition of cyclic GMP hydrolyzing phosphodiesterases 2 and 5 on learning and memory processes and nitric oxide synthase activity in brain during aging

(2008) K. Domek-Łopacińska et al.   BRAIN RESEARCH

Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion

(2008) Eva L. van Donkelaar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Reversal of Oxidative Stress-Induced Anxiety by Inhibition of Phosphodiesterase-2 in Mice

(2008) A. Masood et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Object recognition memory: Neurobiological mechanisms of encoding, consolidation and retrieval

(2008) Boyer D. Winters et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS