Inhibition of MALT1 reduces ferroptosis in rat hearts following ischemia/reperfusion via enhancing the Nrf2/SLC7A11 pathway

Upregulation of FAM129B protects cardiomyocytes from hypoxia/reoxygenation‐induced injury by inhibiting apoptosis, oxidative stress, and inflammatory response via enhancing Nrf2/ ARE activation

(2022) Guangwei Zeng et al.   ENVIRONMENTAL TOXICOLOGY

Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway

(2022) Guang-Hui Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dexmedetomidine post-conditioning alleviates myocardial ischemia–reperfusion injury in rats by ferroptosis inhibition via SLC7A11/GPX4 axis activation

(2022) Peng Yu et al.   Human Cell

Dexmedetomidine attenuates myocardial ischemia/reperfusion-induced ferroptosis via AMPK/GSK-3β/Nrf2 axis

(2022) Zhuoran Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

CARD14 Signalling Ensures Cell Survival and Cancer Associated Gene Expression in Prostate Cancer Cells

(2022) Domien Vanneste et al.   Biomedicines

The Weakened Interaction Between HECTD4 and GluN2B in Ischemic Stroke Promotes Calcium Overload and Brain Injury Through a Mechanism Involving the Decrease of GluN2B and MALT1 Ubiquitination

(2022) Yi-Yue Zhang et al.   MOLECULAR NEUROBIOLOGY

Oxidized phosphatidylcholines trigger ferroptosis in cardiomyocytes during ischemia-reperfusion injury

(2021) Aleksandra Stamenkovic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Inhibition of MALT1 Alleviates Spinal Ischemia/Reperfusion Injury-Induced Neuroinflammation by Modulating Glial Endoplasmic Reticulum Stress in Rats

(2021) Shutian Zhang et al.   Journal of Inflammation Research

Ferulic acid alleviates myocardialischemia reperfusioninjury via upregulating AMPKα2 expression-mediated ferroptosis depression

(2021) Xinliang Liu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Hepcidin Promoted Ferroptosis through Iron Metabolism which Is Associated with DMT1 Signaling Activation in Early Brain Injury following Subarachnoid Hemorrhage

(2021) Hongxia Zhang et al.   Oxidative Medicine and Cellular Longevity

UAMC-3203 OR/and Deferoxamine Improve Post-Resuscitation Myocardial Dysfunction Through Suppressing Ferroptosis In A Rat Model of Cardiac Arrest

(2021) Tao Jin et al.   SHOCK

Role of ferroptosis in promoting cardiotoxicity induced by Imatinib Mesylate via down-regulating Nrf2 pathways in vitro and in vivo

(2021) Chengzhu Song et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Naringenin alleviates myocardial ischemia/reperfusion injury by regulating the nuclear factor-erythroid factor 2-related factor 2 (Nrf2) /System xc-/ glutathione peroxidase 4 (GPX4) axis to inhibit ferroptosis

(2021) Shujun Xu et al.   Bioengineered

Iron metabolism and iron disorders revisited in the hepcidin era

(2020) Clara Camaschella et al.   HAEMATOLOGICA

Pharmacological Inhibition of MALT1 Protease Leads to a Progressive IPEX-Like Pathology

(2020) Kea Martin et al.   Frontiers in Immunology

Ferroptosis occurs in phase of reperfusion but not ischemia in rat heart following ischemia or ischemia/reperfusion

(2020) Li-Jing Tang et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Genetic iron overload disorders

(2020) Elena Corradini et al.   MOLECULAR ASPECTS OF MEDICINE

USP22 Protects Against Myocardial Ischemia–Reperfusion Injury via the SIRT1-p53/SLC7A11–Dependent Inhibition of Ferroptosis–Induced Cardiomyocyte Death

(2020) Shuxian Ma et al.   Frontiers in Physiology

Liproxstatin-1 protects the mouse myocardium against ischemia/reperfusion injury by decreasing VDAC1 levels and restoring GPX4 levels

(2019) Yansheng Feng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Wide-range effects of the MALT-1 inhibitor Mi-2 in CLL cells results in apoptosis

(2018) Nili Dezorella et al.   LEUKEMIA & LYMPHOMA

The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate

(2017) Pranavi Koppula et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel pathway of NADPH oxidase/vascular peroxidase 1 in mediating oxidative injury following ischemia–reperfusion

(2012) Yi-Shuai Zhang et al.   BASIC RESEARCH IN CARDIOLOGY

Cleavage by MALT1 induces cytosolic release of A20

(2010) Claire Malinverni et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Malt1 and cIAP2–Malt1 as effectors of NF-κB activation: Kissing cousins or distant relatives?

(2009) Lara M. Kingeter et al.   CELLULAR SIGNALLING

T cell antigen receptor stimulation induces MALT1 paracaspase–mediated cleavage of the NF-κB inhibitor A20

(2008) Beatrice Coornaert et al.   NATURE IMMUNOLOGY