Discovery of 6-aryl-2-(3,4,5-trimethoxyphenyl)thiazole[3,2-b][1,2,4]triazoles as potent tubulin polymerization inhibitors

Rational design, synthesis and biological evaluation of novel 2-(substituted amino)-[1,2,4]triazolo[1,5-a]pyrimidines as novel tubulin polymerization inhibitors

(2022) Lin Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines

(2021) Xian-Sen Huo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Development of triazolothiadiazine derivatives as highly potent tubulin polymerization inhibitors: Structure-activity relationship, in vitro and in vivo study

(2020) Weifeng Ma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of 3,4-diaryl-1,2,5-Oxadiazole-2/5-Oxides as highly potent inhibitors of tubulin polymerization

(2019) Yilang Hong et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

An overview of tubulin modulators deposited in protein data bank

(2019) Haowei Guo et al.   MEDICINAL CHEMISTRY RESEARCH

Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities

(2019) Fang Yang et al.   BIOORGANIC CHEMISTRY

Recent advances in trimethoxyphenyl (TMP) based tubulin inhibitors targeting the colchicine binding site

(2018) Ling Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues

(2017) Muhamad Mustafa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Natural antitubulin agents: Importance of 3,4,5-trimethoxyphenyl fragment

(2015) Arvind S. Negi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

3-(3-Hydroxy-4-methoxyphenyl)-4-(3,4,5-trimethoxyphenyl)-1,2,5-selenadiazole (G-1103), a novel combretastatin A-4 analog, induces G2/M arrest and apoptosis by disrupting tubulin polymerization in human cervical HeLa cells and fibrosarcoma HT-1080 cells

(2015) Daiying Zuo et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Advances in Computational Structure-Based Drug Design and Application in Drug Discovery

(2015) Tao Wang et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

3-(3,4,5-Trimethoxyphenylselenyl)-1H-indoles and their selenoxides as combretastatin A-4 analogs: Microwave-assisted synthesis and biological evaluation

(2015) Zhiyong Wen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Targeting Mitosis in Cancer: Emerging Strategies

(2015) Carmen Dominguez-Brauer et al.   MOLECULAR CELL

Synthesis and evaluation of benzimidazole carbamates bearing indole moieties for antiproliferative and antitubulin activities

(2014) Qi Guan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

β-Lactam Estrogen Receptor Antagonists and a Dual-Targeting Estrogen Receptor/Tubulin Ligand

(2014) Niamh M. O’Boyle et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization

(2014) Andrea E. Prota et al.   JOURNAL OF MOLECULAR BIOLOGY

A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs

(2014) A. E. Prota et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis and Biological Evaluation of 2,4,5-Substituted Pyrimidines as a New Class of Tubulin Polymerization Inhibitors

(2011) Fuchun Xie et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties☆

(2009) Stefania-Felicia Barbuceanu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships

(2009) Yan Lu et al.   JOURNAL OF MEDICINAL CHEMISTRY