Alkynol natural products target ALDH2 in cancer cells by irreversible binding to the active site

Chemoproteomic Evaluation of the Polyacetylene Callyspongynic Acid

(2015) Sabrina Nickel et al.   CHEMISTRY-A EUROPEAN JOURNAL

Dietary Acetylenic Oxylipin Falcarinol Differentially Modulates GABAA Receptors

(2014) Marta Magdalena Czyzewska et al.   JOURNAL OF NATURAL PRODUCTS

Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system

(2014) A. D. Ebert et al.   Science Translational Medicine

Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

(2013) Zhengqiu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CatalyticZ-Selective Cross-Metathesis with Secondary Silyl- and Benzyl-Protected Allylic Ethers: Mechanistic Aspects and Applications to Natural Product Synthesis

(2013) Tyler J. Mann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dietary polyacetylenes of the falcarinol type are inhibitors of breast cancer resistance protein (BCRP/ABCG2)

(2013) Kee W. Tan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Duocarmycin Analogues Target Aldehyde Dehydrogenase 1 in Lung Cancer Cells

(2012) Tanja Wirth et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy

(2012) Jürgen Eirich et al.   Molecular BioSystems

Polyacetylenes from Panax stipuleanatus and their Cytotoxic Effects on Human Cancer Cells

(2011) Chun Liang et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

From Highly Enantioselective Catalytic Reaction of 1,3-Diynes with Aldehydes to Facile Asymmetric Synthesis of Polycyclic Compounds

(2011) Mark Turlington et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin

(2010) Marco Leonti et al.   BIOCHEMICAL PHARMACOLOGY

Activity-based probes: discovering new biology and new drug targets

(2010) William P. Heal et al.   CHEMICAL SOCIETY REVIEWS

Activity-based probes as a tool for functional proteomic analysis of proteases

(2008) Marko Fonović et al.   Expert Review of Proteomics