Diversity of hydrodynamic radii of intrinsically disordered proteins

Quantitative reconstitution of yeast RNA processing bodies

(2023) Simon L. Currie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational Dynamics of Intrinsically Disordered Proteins Regulate Biomolecular Condensate Chemistry

(2022) Anton Abyzov et al.   CHEMICAL REVIEWS

On the role of phase separation in the biogenesis of membraneless compartments

(2022) Andrea Musacchio   EMBO JOURNAL

ColabFold: making protein folding accessible to all

(2022) Milot Mirdita et al.   NATURE METHODS

Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins

(2022) Francesco Pesce et al.   BIOPHYSICAL JOURNAL

Phosphorylation-dependent regulation of messenger RNA transcription, processing and translation within biomolecular condensates

(2021) Michael L. Nosella et al.   CURRENT OPINION IN CELL BIOLOGY

The role of liquid–liquid phase separation in regulating enzyme activity

(2021) Brian G. O'Flynn et al.   CURRENT OPINION IN CELL BIOLOGY

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

A cryo-electron microscopy support film formed by 2D crystals of hydrophobin HFBI

(2021) Hongcheng Fan et al.   Nature Communications

Orchestration of signaling by structural disorder in class 1 cytokine receptors

(2020) Pernille Seiffert et al.   Cell Communication and Signaling

Conformational Ensembles of an Intrinsically Disordered Protein Consistent with NMR, SAXS, and Single-Molecule FRET

(2020) Gregory-Neal W. Gomes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Revealing the Hidden Sensitivity of Intrinsically Disordered Proteins to their Chemical Environment

(2020) David Moses et al.   Journal of Physical Chemistry Letters

Sequence Effects on Size, Shape, and Structural Heterogeneity in Intrinsically Disordered Proteins

(2019) Upayan Baul et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

The Functionally Important N-Terminal Half of Fission Yeast Mid1p Anillin Is Intrinsically Disordered and Undergoes Phase Separation

(2019) Moon Chatterjee et al.   BIOCHEMISTRY

The Biomineralization Proteome: Protein Complexity for a Complex Bioceramic Assembly Process

(2019) John Spencer Evans   PROTEOMICS

Diffusion coefficients of elastic macromolecules

(2019) Bogdan Cichocki et al.   JOURNAL OF FLUID MECHANICS

TDP-43 and FUS–structural insights into RNA recognition and self-association

(2019) Fionna E Loughlin et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Intrinsically Disordered Protein Ntr2 Modulates the Spliceosomal RNA Helicase Brr2

(2018) Jan Wollenhaupt et al.   BIOPHYSICAL JOURNAL

Phase Transitions in the Assembly and Function of Human miRISC

(2018) Jessica Sheu-Gruttadauria et al.   CELL

Sequence-to-Conformation Relationships of Disordered Regions Tethered to Folded Domains of Proteins

(2018) Anuradha Mittal et al.   JOURNAL OF MOLECULAR BIOLOGY

Looking at the Disordered Proteins through the Computational Microscope

(2018) Payel Das et al.   ACS Central Science

Intrinsic Disorder and Posttranslational Modifications: The Darker Side of the Biological Dark Matter

(2018) April L. Darling et al.   Frontiers in Genetics

The intrinsically disordered C-terminal F domain of the ecdysteroid receptor from Aedes aegypti exhibits metal ion-binding ability

(2018) Anna Więch et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Extreme disorder in an ultrahigh-affinity protein complex

(2018) Alessandro Borgia et al.   NATURE

Long-range regulation of p53 DNA binding by its intrinsically disordered N-terminal transactivation domain

(2018) Alexander S. Krois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Realistic Ensemble Models of Intrinsically Disordered Proteins Using a Structure-Encoding Coil Database

(2018) Alejandro Estaña et al.   STRUCTURE

The Proline/Glycine-Rich Region of the Biofilm Adhesion Protein Aap Forms an Extended Stalk that Resists Compaction

(2017) Alexander E. Yarawsky et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Dynamics of the GW182 Silencing Domain Including its RNA Recognition motif (RRM) Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry

(2017) Maja K. Cieplak-Rotowska et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Intrinsic α helix propensities compact hydrodynamic radii in intrinsically disordered proteins

(2017) Lance R. English et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Hydrodynamic Radii of Intrinsically Disordered Proteins Determined from Experimental Polyproline II Propensities

(2016) Maria E. Tomasso et al.   PLoS Computational Biology

Structural Ensembles of Intrinsically Disordered Proteins Depend Strongly on Force Field: A Comparison to Experiment

(2015) Sarah Rauscher et al.   Journal of Chemical Theory and Computation

Poly(A)-specific ribonuclease deficiency impacts telomere biology and causes dyskeratosis congenita

(2015) Hemanth Tummala et al.   JOURNAL OF CLINICAL INVESTIGATION

Polymer physics of intracellular phase transitions

(2015) Clifford P. Brangwynne et al.   Nature Physics

Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression

(2014) D. Bhandari et al.   GENES & DEVELOPMENT

Structural and Biochemical Insights to the Role of the CCR4-NOT Complex and DDX6 ATPase in MicroRNA Repression

(2014) Hansruedi Mathys et al.   MOLECULAR CELL

Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch

(2014) Alaji Bah et al.   NATURE

Alanine and proline content modulate global sensitivity to discrete perturbations in disordered proteins

(2014) Romel B. Perez et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Poly(A)-specific ribonuclease (PARN): An allosterically regulated, processive and mRNA cap-interacting deadenylase

(2013) Anders Virtanen et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by tristetraprolin

(2013) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Temperature effects on the hydrodynamic radius of the intrinsically disordered N-terminal region of the p53 protein

(2013) Timothy D. Langridge et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Translational diffusion coefficients of macromolecules

(2012) R. Rodríguez Schmidt et al.   EUROPEAN PHYSICAL JOURNAL E

Structural Ensemble of an Intrinsically Disordered Polypeptide

(2012) Jeetain Mittal et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy

(2012) H. Hofmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global architecture of human poly(A)-specific ribonuclease by atomic force microscopy in liquid and dynamic light scattering

(2011) Anna Niedzwiecka et al.   BIOPHYSICAL CHEMISTRY

FRET and FCS-Friends or Foes?

(2011) Harekrushna Sahoo et al.   CHEMPHYSCHEM

Intrinsically disordered proteins: regulation and disease

(2011) M Madan Babu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT

(2011) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Beyond the Random Coil: Stochastic Conformational Switching in Intrinsically Disordered Proteins

(2011) Ucheor B. Choi et al.   STRUCTURE

Sequence Determinants of Compaction in Intrinsically Disordered Proteins

(2010) Joseph A. Marsh et al.   BIOPHYSICAL JOURNAL

Structural Disorder within Henipavirus Nucleoprotein and Phosphoprotein: From Predictions to Experimental Assessment

(2010) Johnny Habchi et al.   PLoS One

Charge interactions can dominate the dimensions of intrinsically disordered proteins

(2010) S. Muller-Spath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Transcriptional Repressor RYBP Is a Natively Unfolded Protein Which Folds upon Binding to DNA†

(2009) José L. Neira et al.   BIOCHEMISTRY

Intrinsically Disordered Proteins and Their Environment: Effects of Strong Denaturants, Temperature, pH, Counter Ions, Membranes, Binding Partners, Osmolytes, and Macromolecular Crowding

(2009) Vladimir N. Uversky   PROTEIN JOURNAL

Structural Basis of m7GpppG Binding to Poly(A)-Specific Ribonuclease

(2009) Mousheng Wu et al.   STRUCTURE

The Intrinsically Disordered RNR Inhibitor Sml1 Is a Dynamic Dimer†

(2008) Jens Danielsson et al.   BIOCHEMISTRY

Structural Characterization of Binding of Cu(II) to Tau Protein†

(2008) Alice Soragni et al.   BIOCHEMISTRY

Starmaker Exhibits Properties of an Intrinsically Disordered Protein

(2008) Tomasz M. Kapłon et al.   BIOMACROMOLECULES

Biophysical Characterization of the Unstructured Cytoplasmic Domain of the Human Neuronal Adhesion Protein Neuroligin 3

(2008) Aviv Paz et al.   BIOPHYSICAL JOURNAL

Dark States in Monomeric Red Fluorescent Proteins Studied by Fluorescence Correlation and Single Molecule Spectroscopy

(2008) Jelle Hendrix et al.   BIOPHYSICAL JOURNAL

An Unusual Intrinsically Disordered Protein from the Model LegumeLotus japonicusStabilizes Proteinsin Vitro

(2008) Svend Haaning et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation at Ser-129 but Not the Phosphomimics S129E/D Inhibits the Fibrillation of α-Synuclein

(2008) Katerina E. Paleologou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution Conformation, Backbone Dynamics and Lipid Interactions of the Intrinsically Unstructured Malaria Surface Protein MSP2

(2008) Xuecheng Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Intrinsically Unstructured Domains of Arf and Hdm2 Form Bimolecular Oligomeric Structures In Vitro and In Vivo

(2008) Sivashankar G. Sivakolundu et al.   JOURNAL OF MOLECULAR BIOLOGY

Intramolecular Cohesion of Coils Mediated by Phenylalanine–Glycine Motifs in the Natively Unfolded Domain of a Nucleoporin

(2008) V. V. Krishnan et al.   PLoS Computational Biology

Precise Measurement of Diffusion Coefficients using Scanning Fluorescence Correlation Spectroscopy

(2007) Zdeněk Petrášek et al.   BIOPHYSICAL JOURNAL

Modeling the accessible conformations of the intrinsically unstructured transactivation domain of p53

(2007) David F. Lowry et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Human full-length Securin is a natively unfolded protein

(2005) Nuria Sánchez-Puig et al.   PROTEIN SCIENCE