Anti-ischemic drug trimetazidine blocks mercury nephrotoxicity by suppressing renal redox imbalance, inflammatory stress and caspase-dependent apoptosis in rats

Astaxanthin: A promising therapeutic agent for organ fibrosis

(2023) Ke Li et al.   PHARMACOLOGICAL RESEARCH

Mercuric Chloride Induced Nephrotoxicity: Ameliorative Effect of Carica papaya Leaves Confirmed by Histopathology, Immunohistochemistry, and Gene Expression Studies

(2023) Yuvaraj Maria Francis et al.   ACS Omega

Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation

(2022) Ademola C. Famurewa et al.   BIOMEDICINE & PHARMACOTHERAPY

Carveol ameliorates mercury-induced oxidative stress, neuroinflammation, and neurodegeneration in a mouse brain

(2022) Abdullah Alattar et al.   NEUROTOXICOLOGY

A Systematic Review of Mercury Exposures from Skin-Lightening Products

(2022) Ashley Bastiansz et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Banana peel ameliorated hepato-renal damage and exerted anti-inflammatory and anti-apoptotic effects in metal mixture mediated hepatic nephropathy by activation of Nrf2/ Hmox-1 and inhibition of Nfkb pathway

(2022) Boma F. Eddie-Amadi et al.   FOOD AND CHEMICAL TOXICOLOGY

Mercury Contamination in Fish and Its Effects on the Health of Pregnant Women and Their Fetuses, and Guidance for Fish Consumption—A Narrative Review

(2022) Bojian Chen et al.   International Journal of Environmental Research and Public Health

Oxidative Stress and Antioxidants—A Critical Review on In Vitro Antioxidant Assays

(2022) Raghavendhar R. Kotha et al.   Antioxidants

Vitamin E and Lactobacillus Provide Protective Effects Against Liver Injury Induced by HgCl2: Role of CHOP, GPR87, and mTOR Proteins

(2021) Ahlam Alhusaini et al.   Dose-Response

Protective effect of diosmin against doxorubicin-induced nephrotoxicity

(2021) Nemat Ali et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Trimetazidine an emerging paradigm in renal therapeutics: Preclinical and clinical insights

(2021) Kirti Gupta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effect of rutin on mercuric chloride‐induced reproductive damage in male rats

(2020) Fatih Mehmet Kandemir et al.   ANDROLOGIA

Metformin and trimetazidine ameliorate diabetes-induced cognitive impediment in status epileptic rats

(2020) Marwan Abd Elbaset Mohamed et al.   EPILEPSY & BEHAVIOR

Ginger juice prevents cisplatin‐induced oxidative stress, endocrine imbalance and NO/iNOS/NF‐κB signalling via modulating testicular redox‐inflammatory mechanism in rats

(2020) Ademola C. Famurewa et al.   ANDROLOGIA

Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1

(2020) Yong Yang et al.   Frontiers in Pharmacology

Mercury Exposure and Associations with Hyperlipidemia and Elevated Liver Enzymes: A Nationwide Cross-Sectional Survey

(2020) Seungho Lee et al.   Toxics

Similar hepatoprotective effectiveness of Diphenyl diselenide and Ebselen against cisplatin-induced disruption of metabolic homeostasis and redox balance in juvenile rats

(2020) Bruna C.W. Fulco et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Zinc abrogates anticancer drug tamoxifen-induced hepatotoxicity by suppressing redox imbalance, NO/iNOS/NF-ĸB signaling, and caspase-3-dependent apoptosis in female rats

(2019) Ademola C. Famurewa et al.   TOXICOLOGY MECHANISMS AND METHODS

Sodium/calcium overload and Sirt1/Nrf2/OH-1 pathway are critical events in mercuric chloride-induced nephrotoxicity

(2019) Siwen Li et al.   CHEMOSPHERE

Neuroprotective role of naringenin against methylmercury induced cognitive impairment and mitochondrial damage in a mouse model

(2019) Adwaid Manu Krishna Chandran et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Trimetazidine in conditions other than coronary disease, old drug, new tricks?

(2017) Hai Zou et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Dietary luteolin attenuates chronic liver injury induced by mercuric chloride via the Nrf2/NF-κB/P53 signaling pathway in rats

(2017) Haili Zhang et al.   Oncotarget

The protective effect of trimetazidine against cisplatin-induced nephrotoxicity in rats

(2016) Nagla A. El-Sherbeeny et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Regulation of Sirt1/Nrf2/TNF-α signaling pathway by luteolin is critical to attenuate acute mercuric chloride exposure induced hepatotoxicity

(2016) Daqian Yang et al.   Scientific Reports

Means of evaluation and protection from doxorubicin-induced cardiotoxicity and hepatotoxicity in rats

(2014) Issam Salouege et al.   Journal of Cancer Research and Therapeutics

Nephroprotective potential of selenium and taurine against mercuric chloride induced nephropathy in rats

(2014) Fatma E. Agha et al.   RENAL FAILURE

Mechanisms underlying protective effects of trimetazidine on endothelial progenitor cells biological functions against H2O2-induced injury: Involvement of antioxidation and Akt/eNOS signaling pathways

(2013) Qinqin Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glutathione as an antioxidant in inorganic mercury induced nephrotoxicity

(2011) QMR Haq et al.   Journal of Postgraduate Medicine

Delayed biochemical changes induced by mercury intoxication are prevented by zinc pre-exposure

(2010) C. Franciscato et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY