Advanced glycation end products impair coronary artery BK channels via AMPK/Akt/FBXO32 signaling pathway

Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53

(2021) Peng Jiang et al.   MOLECULAR CELL

Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling

(2021) Feng-ling Ning et al.   ACTA PHARMACOLOGICA SINICA

Coronary Large Conductance Ca2+-Activated K+ Channel Dysfunction in Diabetes Mellitus

(2021) Tong Lu et al.   Frontiers in Physiology

Glucose fluctuations promote vascular BK channels dysfunction via PKCα/NF-κB/MuRF1 signaling

(2020) Zhen-Ye Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Advanced glycation end-products suppress autophagy by AMPK/mTOR signaling pathway to promote vascular calcification

(2020) Yanyan Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

AMPK is associated with the beneficial effects of antidiabetic agents on cardiovascular diseases

(2019) Qingguo Lu et al.   BIOSCIENCE REPORTS

Impact of advanced glycation end products (AGEs) signaling in coronary artery disease

(2019) Marinos Kosmopoulos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

AGEs impair Kv channel-mediated vasodilation of coronary arteries by activating the NF-κB signaling pathway in ZDF rats

(2019) Qingbo Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Glucagon-like peptide-1 increased the vascular relaxation response via AMPK/Akt signaling in diabetic mice aortas

(2019) Kumiko Taguchi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Advanced Glycation End Products: Potential Mechanism and Therapeutic Target in Cardiovascular Complications under Diabetes

(2019) Ping Yang et al.   Oxidative Medicine and Cellular Longevity

Incidence of Hospitalisation for Heart Failure and Case-Fatality Among 3.25 Million People with and without Diabetes

(2018) David A. McAllister et al.   CIRCULATION

Regulation of Coronary Arterial Large Conductance Ca2+-Activated K+ Channel Protein Expression and Function by n-3 Polyunsaturated Fatty Acids in Diabetic Rats

(2017) Xu Tang et al.   JOURNAL OF VASCULAR RESEARCH

Diallyl trisulfide exerts cardioprotection against myocardial ischemia-reperfusion injury in diabetic state, role of AMPK-mediated AKT/GSK-3β/HIF-1α activation

(2017) Liming Yu et al.   Oncotarget

Molecular Mechanisms Underlying Renin-Angiotensin-Aldosterone System Mediated Regulation of BK Channels

(2017) Zhen-Ye Zhang et al.   Frontiers in Physiology

Coronary arterial BK channel dysfunction exacerbates ischemia/reperfusion-induced myocardial injury in diabetic mice

(2016) Tong Lu et al.   Applied Physiology Nutrition and Metabolism

AMPK Dilates Resistance Arteries via Activation of SERCA and BKCaChannels in Smooth MuscleNovelty and Significance

(2015) Holger Schneider et al.   HYPERTENSION

Molecular basis for differential modulation of BK channel voltage-dependent gating by auxiliary γ subunits

(2015) Qin Li et al.   JOURNAL OF GENERAL PHYSIOLOGY

Advanced Glycation End Products Impair Voltage-Gated K+ Channels-Mediated Coronary Vasodilation in Diabetic Rats

(2015) Wen Su et al.   PLoS One

AKAP150 Contributes to Enhanced Vascular Tone by Facilitating Large-Conductance Ca 2+ -Activated K + Channel Remodeling in Hyperglycemia and Diabetes Mellitus

(2013) Matthew A. Nystoriak et al.   CIRCULATION RESEARCH

Reactive Oxygen Species Signaling Facilitates FOXO-3a/FBXO-Dependent Vascular BK Channel  1 Subunit Degradation in Diabetic Mice

(2012) T. Lu et al.   DIABETES

Higher Plasma Levels of Advanced Glycation End Products Are Associated With Incident Cardiovascular Disease and All-Cause Mortality in Type 1 Diabetes: A 12-year follow-up study

(2011) J. W. Nin et al.   DIABETES CARE

Activation of vascular BK channels by docosahexaenoic acid is dependent on cytochrome P450 epoxygenase activity

(2010) R.-x. Wang et al.   CARDIOVASCULAR RESEARCH

Muscle-Specific F-Box Only Proteins Facilitate BK Channel β 1 Subunit Downregulation in Vascular Smooth Muscle Cells of Diabetes Mellitus

(2010) Dai-min Zhang et al.   CIRCULATION RESEARCH