Cellular senescence promotes progenitor cell expansion during axolotl limb regeneration

WNT/beta-catenin signalling interrupts a senescence-induction cascade in human mesenchymal stem cells that restricts their expansion

(2022) Johannes Lehmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Canonical Wnt signaling and the regulation of divergent mesenchymal Fgf8 expression in axolotl limb development and regeneration

(2022) Giacomo L Glotzer et al.   eLife

Wnt Signaling Coordinates the Expression of Limb Patterning Genes During Axolotl Forelimb Development and Regeneration

(2022) Alexander M. Lovely et al.   Frontiers in Cell and Developmental Biology

Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

(2022) Victoria Moiseeva et al.   NATURE

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

Senescence and the SASP: many therapeutic avenues

(2020) Jodie Birch et al.   GENES & DEVELOPMENT

Cells exhibiting strong p16INK4a promoter activation in vivo display features of senescence

(2019) Jie-Yu Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads

(2019) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

Senolytic therapies for healthy longevity

(2019) Jan M. van Deursen   SCIENCE

Notch Signaling Mediates Secondary Senescence

(2019) Yee Voan Teo et al.   Cell Reports

Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

(2019) Asimina Pantazi et al.   AGING CELL

Transient p53-Mediated Regenerative Senescence in the Injured Heart

(2019) Rachel Sarig et al.   CIRCULATION

Cell senescence contributes to tissue regeneration in zebrafish

(2019) Sabela Da Silva‐Álvarez et al.   AGING CELL

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

Can laboratory model systems instruct human limb regeneration?

(2019) Ben D. Cox et al.   DEVELOPMENT

A versatile drug delivery system targeting senescent cells

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Cellular senescence in tissue repair: every cloud has a silver lining

(2018) Maximina H. Yun   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway

(2018) Frédéric Lessard et al.   NATURE CELL BIOLOGY

Paracrine cellular senescence exacerbates biliary injury and impairs regeneration

(2018) Sofia Ferreira-Gonzalez et al.   Nature Communications

Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration

(2018) Tobias Gerber et al.   SCIENCE

TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence

(2018) Thomas G. Bird et al.   Science Translational Medicine

iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data

(2018) Steven Xijin Ge et al.   BMC BIOINFORMATICS

The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

(2017) Birgit Ritschka et al.   GENES & DEVELOPMENT

Senescence-associated reprogramming promotes cancer stemness

(2017) Maja Milanovic et al.   NATURE

Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells

(2016) Brandon M. Hall et al.   Aging-US

The Molecular and Cellular Choreography of Appendage Regeneration

(2016) Elly M. Tanaka   CELL

Essential Role for Premature Senescence of Myofibroblasts in Myocardial Fibrosis

(2016) Kathleen Meyer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

FGF8 and SHH substitute for anterior–posterior tissue interactions to induce limb regeneration

(2016) Eugeniu Nacu et al.   NATURE

NOTCH1 mediates a switch between two distinct secretomes during senescence

(2016) Matthew Hoare et al.   NATURE CELL BIOLOGY

Perturbation of Ribosome Biogenesis Drives Cells into Senescence through 5S RNP-Mediated p53 Activation

(2015) Kazuho Nishimura et al.   Cell Reports

Recurrent turnover of senescent cells during regeneration of a complex structure

(2015) Maximina H Yun et al.   eLife

Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability

(2015) Tae-Hyung Kim et al.   Oncotarget

An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA

(2014) Marco Demaria et al.   DEVELOPMENTAL CELL

Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

An overview of pre-ribosomal RNA processing in eukaryotes

(2014) Anthony K. Henras et al.   Wiley Interdisciplinary Reviews-RNA

Programmed Cell Senescence during Mammalian Embryonic Development

(2013) Daniel Muñoz-Espín et al.   CELL

Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning

(2013) Mekayla Storer et al.   CELL

Patterning and growth control by membrane-tethered Wingless

(2013) Cyrille Alexandre et al.   NATURE

Aging, Cellular Senescence, and Cancer

(2012) Judith Campisi   Annual Review of Physiology

Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B

(2012) Yu Sun et al.   NATURE MEDICINE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

(2010) Joon-Il Jun et al.   NATURE CELL BIOLOGY

The role of Dpp and Wg in compensatory proliferation and in the formation of hyperplastic overgrowths caused by apoptotic cells in the Drosophila wing disc

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Comparative Aspects of Animal Regeneration

(2008) Jeremy P. Brockes et al.   Annual Review of Cell and Developmental Biology

Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network

(2008) Thomas Kuilman et al.   CELL

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY