Wheel Running Adversely Affects Disease Onset and Neuromuscular Interplay in Amyotrophic Lateral Sclerosis Slow Progression Mouse Model

Physical activity as an exogenous risk factor for amyotrophic lateral sclerosis: a review of the evidence

(2023) Laura Chapman et al.   BRAIN

Intramuscular IL-10 Administration Enhances the Activity of Myogenic Precursor Cells and Improves Motor Function in ALS Mouse Model

(2023) Paola Fabbrizio et al.   Cells

A 3D cell culture system for bioengineering human neuromuscular junctions to model ALS

(2023) Bita Massih et al.   Frontiers in Cell and Developmental Biology

Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models

(2023) Cassandra Margotta et al.   Inflammation and Regeneration

Neuromuscular Junction Dysfunction in Amyotrophic Lateral Sclerosis

(2022) Sagar Verma et al.   MOLECULAR NEUROBIOLOGY

A systematic review on the risk of neurodegenerative diseases and neurocognitive disorders in professional and varsity athletes

(2022) G. Bellomo et al.   NEUROLOGICAL SCIENCES

Mixed Comparison of Different Exercise Interventions for Function, Respiratory, Fatigue, and Quality of Life in Adults With Amyotrophic Lateral Sclerosis: Systematic Review and Network Meta-Analysis

(2022) Yining Zhu et al.   Frontiers in Aging Neuroscience

Visceral Adipose Tissue E2F1-miRNA206/210 Pathway Associates with Type 2 Diabetes in Humans with Extreme Obesity

(2022) Nitzan Maixner et al.   Cells

Systematic Review of Therapeutic Physical Exercise in Patients with Amyotrophic Lateral Sclerosis over Time

(2021) Laura Ortega-Hombrados et al.   International Journal of Environmental Research and Public Health

Aerobic, resistance and combined exercise training for patients with amyotrophic lateral sclerosis: A systematic review and meta-analysis

(2021) Masoud Rahmati et al.   Physiotherapy

Physical exercise is a risk factor for amyotrophic lateral sclerosis: Convergent evidence from Mendelian randomisation, transcriptomics and risk genotypes

(2021) Thomas H Julian et al.   EBioMedicine

Circulating myomiRs in Muscle Denervation: From Surgical to ALS Pathological Condition

(2021) Irene Casola et al.   Cells

Incidence of and Mortality From Amyotrophic Lateral Sclerosis in National Football League Athletes

(2021) Daniel H. Daneshvar et al.   JAMA Network Open

The influence of metallothionein treatment and treadmill running exercise on disease onset and survival in SOD1 G93A amyotrophic lateral sclerosis mice

(2020) Katherine E. A. Lewis et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Effects of Exercise in Patients with Amyotrophic Lateral Sclerosis

(2020) MENG Lijiao et al.   AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION

Differential Regulatory Roles of MicroRNAs in Porcine Intramuscular and Subcutaneous Adipocytes

(2020) Ke Xu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Disease propagation in amyotrophic lateral sclerosis (ALS): an interplay between genetics and environment

(2020) Sarah Schram et al.   Journal of Neuroinflammation

The genetic architecture of ALS

(2020) Aleksey Shatunov et al.   NEUROBIOLOGY OF DISEASE

The Role of Exercise as a Non-pharmacological Therapeutic Approach for Amyotrophic Lateral Sclerosis: Beneficial or Detrimental?

(2019) Stavroula Tsitkanou et al.   Frontiers in Neurology

Neuromuscular Junction as an Entity of Nerve-Muscle Communication

(2019) Elisa Lepore et al.   Cells

Running and swimming prevent the deregulation of the BDNF/TrkB neurotrophic signalling at the neuromuscular junction in mice with amyotrophic lateral sclerosis

(2019) Laia Just-Borràs et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Muscle Expression of SOD1G93A Triggers the Dismantlement of Neuromuscular Junction via PKC-Theta

(2018) Gabriella Dobrowolny et al.   ANTIOXIDANTS & REDOX SIGNALING

Swim Training Modulates Skeletal Muscle Energy Metabolism, Oxidative Stress, and Mitochondrial Cholesterol Content in Amyotrophic Lateral Sclerosis Mice

(2018) Damian Jozef Flis et al.   Oxidative Medicine and Cellular Longevity

Metabolic Changes Associated With Muscle Expression of SOD1G93A

(2018) Gabriella Dobrowolny et al.   Frontiers in Physiology

Prolonged Voluntary Running Negatively Affects Survival and Disease Prognosis of Male SOD1G93A Low-Copy Transgenic Mice

(2018) Luciana Garbugino et al.   Frontiers in Behavioral Neuroscience

Genetic epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis

(2017) Zhang-Yu Zou et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

What is “Hyper” in the ALS Hypermetabolism?

(2017) Alberto Ferri et al.   MEDIATORS OF INFLAMMATION

Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice

(2017) Céline Desseille et al.   Frontiers in Molecular Neuroscience

New Insights on the Mechanisms of Disease Course Variability in ALS from Mutant SOD1 Mouse Models

(2016) Giovanni Nardo et al.   BRAIN PATHOLOGY

Decoding ALS: from genes to mechanism

(2016) J. Paul Taylor et al.   NATURE

Long-term physical activity: an exogenous risk factor for sporadic amyotrophic lateral sclerosis?

(2016) Ceryl A. Harwood et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Familial Amyotrophic Lateral Sclerosis

(2015) Kevin Boylan   NEUROLOGIC CLINICS

Early motor deficits in mouse disease models are reliably uncovered using an automated home-cage wheel-running system: a cross-laboratory validation

(2014) S. Mandillo et al.   Disease Models & Mechanisms

Body mass index and dietary intervention: Implications for prognosis of amyotrophic lateral sclerosis

(2014) S.T. Ngo et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Rehabilitation in amyotrophic lateral sclerosis: Why it matters

(2014) Salony Majmudar et al.   MUSCLE & NERVE

The phenotypic variability of amyotrophic lateral sclerosis

(2014) Bart Swinnen et al.   Nature Reviews Neurology

Wheel running in the wild

(2014) J. H. Meijer et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Triathletes are over-represented in a population of patients with ALS

(2014) Marc Gotkine et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Muscle histone deacetylase 4 upregulation in amyotrophic lateral sclerosis: potential role in reinnervation ability and disease progression

(2013) Gaëlle Bruneteau et al.   BRAIN

Mice lacking the Parkinson's related GPR37/PAEL receptor show non-motor behavioral phenotypes: age and gender effect

(2013) S. Mandillo et al.   GENES BRAIN AND BEHAVIOR

Lifetime physical activity and the risk of amyotrophic lateral sclerosis

(2013) M. H. B. Huisman et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The epidemiology of ALS: a conspiracy of genes, environment and time

(2013) Ammar Al-Chalabi et al.   Nature Reviews Neurology

Understanding ALS: new therapeutic approaches

(2012) Antonio Musarò   FEBS Journal

Sigma-1R Agonist Improves Motor Function and Motoneuron Survival in ALS Mice

(2012) Renzo Mancuso et al.   Neurotherapeutics

A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis

(2011) A. Acevedo-Arozena et al.   Disease Models & Mechanisms

Amyotrophic lateral sclerosis, physical exercise, trauma and sports: Results of a population-based pilot case-control study

(2010) Ettore Beghi et al.   Amyotrophic Lateral Sclerosis

The epidemiology and treatment of ALS: Focus on the heterogeneity of the disease and critical appraisal of therapeutic trials

(2010) Ettore Beghi et al.   Amyotrophic Lateral Sclerosis

The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity: human and rodent perspectives

(2010) T. Garland et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

The “Dying-Back” Phenomenon of Motor Neurons in ALS

(2010) Michal Dadon-Nachum et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Energy metabolism in amyotrophic lateral sclerosis

(2010) Luc Dupuis et al.   LANCET NEUROLOGY

Appropriate Physical Activity Intervention Strategies for Weight Loss and Prevention of Weight Regain for Adults

(2010) JOSEPH E. DONNELLY et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Physical activity as an exogenous risk factor in motor neuron disease (MND): A review of the evidence

(2009) Ceryl A. Harwood et al.   Amyotrophic Lateral Sclerosis

ALS in Italian professional soccer players: The risk is still present and could be soccer-specific

(2009) Adriano Chiò et al.   Amyotrophic Lateral Sclerosis

Moderate exercise delays the motor performance decline in a transgenic model of ALS

(2009) Isabel Carreras et al.   BRAIN RESEARCH

Motoneuron survival is promoted by specific exercise in a mouse model of amyotrophic lateral sclerosis

(2009) Séverine Deforges et al.   JOURNAL OF PHYSIOLOGY-LONDON

MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice

(2009) A. H. Williams et al.   SCIENCE

Measuring Mechanical Properties, Including Isotonic Fatigue, of Fast and Slow MLC/mIgf-1 Transgenic Skeletal Muscle

(2008) Zaccaria Del Prete et al.   ANNALS OF BIOMEDICAL ENGINEERING

Skeletal Muscle Is a Primary Target of SOD1G93A-Mediated Toxicity

(2008) Gabriella Dobrowolny et al.   Cell Metabolism

A Histone Deacetylase 4/Myogenin Positive Feedback Loop Coordinates Denervation-dependent Gene Induction and Suppression

(2008) Huibin Tang et al.   MOLECULAR BIOLOGY OF THE CELL

Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study

(2008) Silvia Mandillo et al.   PHYSIOLOGICAL GENOMICS

Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS

(2008) B TURNER et al.   PROGRESS IN NEUROBIOLOGY