Individualized antimicrobial dose optimization: a systematic review and meta-analysis of randomized controlled trials

Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial

(2022) Stefan Hagel et al.   INTENSIVE CARE MEDICINE

Biomarkers Predicting Tissue Pharmacokinetics of Antimicrobials in Sepsis: A Review

(2022) Maria Sanz Codina et al.   CLINICAL PHARMACOKINETICS

Beta-Lactam Antibiotic Therapeutic Drug Monitoring in Critically Ill Patients: A Systematic Review and Meta-Analysis

(2022) Rekha Pai Mangalore et al.   CLINICAL INFECTIOUS DISEASES

Relationship between Pharmacokinetic/Pharmacodynamic Target Attainment and Microbiological Outcome in Critically Ill COVID-19 Patients with Documented Gram-Negative Superinfections Treated with TDM-Guided Continuous-Infusion Meropenem

(2022) Maria Sanz Codina et al.   Pharmaceutics

Model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients: a multicentre randomised clinical trial

(2022) Tim M. J. Ewoldt et al.   INTENSIVE CARE MEDICINE

Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination

(2022) Maria Sanz-Codina et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

From Therapeutic Drug Monitoring to Model‐Informed Precision Dosing for Antibiotics

(2021) Sebastian G. Wicha et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update

(2021) Waleed Alhazzani et al.   CRITICAL CARE MEDICINE

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

(2021) Matthew J. Page et al.   Systematic Reviews

Therapeutic Drug Monitoring of Antibiotics in Critically Ill Patients: Current Practice and Future Perspectives With a Focus on Clinical Outcome

(2021) Birgit C. P. Koch et al.   THERAPEUTIC DRUG MONITORING

Predicting Antimicrobial Activity at the Target Site: Pharmacokinetic/Pharmacodynamic Indices versus Time–Kill Approaches

(2021) Wisse van Os et al.   Antibiotics-Basel

Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#

(2020) Mohd H. Abdul-Aziz et al.   INTENSIVE CARE MEDICINE

External evaluation of population pharmacokinetic models for continuous administration of meropenem in critically ill adult patients

(2020) YL. Wang et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

The use of antibiotics in the intensive care unit of a tertiary hospital in Malawi

(2020) Raphael Kazidule Kayambankadzanja et al.   BMC INFECTIOUS DISEASES

Comment on “Meropenem, Cefepime, and Piperacillin Protein Binding in Patient Samples”

(2020) Uwe Liebchen et al.   THERAPEUTIC DRUG MONITORING

What Antibiotic Exposures Are Required to Suppress the Emergence of Resistance for Gram-Negative Bacteria? A Systematic Review

(2019) Chandra Datta Sumi et al.   CLINICAL PHARMACOKINETICS

Pharmacokinetic variability of beta-lactams in critically ill patients: a narrative review

(2019) Clément Boidin et al.   Anaesthesia Critical Care & Pain Medicine

Building a better test for piperacillin-tazobactam susceptibility testing: Would that it were so simple (It's complicated)

(2019) Andrew Henderson et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Global increase and geographic convergence in antibiotic consumption between 2000 and 2015

(2018) Eili Y. Klein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Time to Treatment and Mortality during Mandated Emergency Care for Sepsis

(2017) Christopher W. Seymour et al.   NEW ENGLAND JOURNAL OF MEDICINE

Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

(2016) Andre C. Kalil et al.   CLINICAL INFECTIOUS DISEASES

Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial

(2015) Fekade Bruck Sime et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Voriconazole therapeutic drug monitoring: results of a prematurely discontinued randomized multicenter trial

(2015) D. Neofytos et al.   Transplant Infectious Disease

Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range

(2015) Xiang Wan et al.   BMC Medical Research Methodology

DALI: Defining Antibiotic Levels in Intensive Care Unit Patients: Are Current  -Lactam Antibiotic Doses Sufficient for Critically Ill Patients?

(2014) J. A. Roberts et al.   CLINICAL INFECTIOUS DISEASES

Protein Binding of β-Lactam Antibiotics in Critically Ill Patients: Can We Successfully Predict Unbound Concentrations?

(2013) Gloria Wong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial

(2013) Jan J. De Waele et al.   INTENSIVE CARE MEDICINE

The Effect of Therapeutic Drug Monitoring on Safety and Efficacy of Voriconazole in Invasive Fungal Infections: A Randomized Controlled Trial

(2012) Wan Beom Park et al.   CLINICAL INFECTIOUS DISEASES

Kidney failure related to broad-spectrum antibiotics in critically ill patients: secondary end point results from a 1200 patient randomised trial

(2012) Jens-Ulrik Stæhr Jensen et al.   BMJ Open

Selection of Resistant Bacteria at Very Low Antibiotic Concentrations

(2011) Erik Gullberg et al.   PLoS Pathogens

How antibiotics kill bacteria: from targets to networks

(2010) Michael A. Kohanski et al.   NATURE REVIEWS MICROBIOLOGY

Ciprofloxacin pharmacokinetics in critically ill patients: A prospective cohort study

(2008) Arthur R.H. van Zanten et al.   JOURNAL OF CRITICAL CARE