Branched-Chain Amino Acid Catabolism Promotes Thrombosis Risk by Enhancing Tropomodulin-3 Propionylation in Platelets

Branched-chain amino acids in disease

(2019) Phillip J. White et al.   SCIENCE

Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance

(2019) Meiyi Zhou et al.   DIABETES

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44

(2019) Takeshi Yoneshiro et al.   NATURE

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase

(2018) Phillip J. White et al.   Cell Metabolism

Histone propionylation is a mark of active chromatin

(2017) Adam F Kebede et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone propionylation is a mark of active chromatin

(2017) Adam F Kebede et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Novel metabolic and physiological functions of branched chain amino acids: a review

(2017) Shihai Zhang et al.   Journal of Animal Science and Biotechnology

mTORC1 promotes aging-related venous thrombosis in mice via elevation of platelet volume and activation

(2016) J. Yang et al.   BLOOD

Catabolic Defect of Branched-Chain Amino Acids Promotes Heart FailureCLINICAL PERSPECTIVE

(2016) Haipeng Sun et al.   CIRCULATION

Oxidized LDL activates blood platelets through CD36/NOX2-mediated inhibition of the cGMP/protein kinase G signaling cascade

(2015) S. Magwenzi et al.   BLOOD

Maximal Oxidative Capacity during Exercise Is Associated with Skeletal Muscle Fuel Selection and Dynamic Changes in Mitochondrial Protein Acetylation

(2015) Katherine A. Overmyer et al.   Cell Metabolism

Metabolic and molecular responses to leucine-enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis

(2015) Cynthia Tsien et al.   HEPATOLOGY

Reviewing the Effects of l-Leucine Supplementation in the Regulation of Food Intake, Energy Balance, and Glucose Homeostasis

(2015) João Pedroso et al.   Nutrients

Lysine Propionylation Is a Prevalent Post-translational Modification inThermus thermophilus

(2014) Hiroki Okanishi et al.   MOLECULAR & CELLULAR PROTEOMICS

Expanding ester biosynthesis in Escherichia coli

(2014) Gabriel M Rodriguez et al.   Nature Chemical Biology

Branched-chain amino acids in metabolic signalling and insulin resistance

(2014) Christopher J. Lynch et al.   Nature Reviews Endocrinology

LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis

(2013) B. Estevez et al.   BLOOD

ADP-Stimulated Activation of Akt During Integrin Outside-In Signaling Promotes Platelet Spreading by Inhibiting Glycogen Synthase Kinase-3β

(2012) Kelly A. O’Brien et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Advanced glycation end products induce a prothrombotic phenotype in mice via interaction with platelet CD36

(2012) W. Zhu et al.   BLOOD

Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance

(2012) Christopher B. Newgard   Cell Metabolism

Impact of Insulin Receptor Substrate-1 Genotypes on Platelet Reactivity and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Coronary Artery Disease

(2011) Dominick J. Angiolillo et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice

(2010) Giuseppe D'Antona et al.   Cell Metabolism

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism