Loss of SMURF2 expression enhances RACK1 stability and promotes ovarian cancer progression

Cancer statistics, 2023

(2023) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

CircVPRBP inhibits nodal metastasis of cervical cancer by impeding RACK1 O-GlcNAcylation and stability

(2023) Chunyu Zhang et al.   ONCOGENE

Molecular, cellular and systemic aspects of epithelial ovarian cancer and its tumor microenvironment

(2022) Esther Schoutrop et al.   SEMINARS IN CANCER BIOLOGY

An unexpected role for BAG3 in regulating PARP1 ubiquitination in oxidative stress-related endothelial damage

(2022) Naijin Zhang et al.   Redox Biology

Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation

(2022) Bojie Lin et al.   Cell Death Discovery

Fbxo45‐mediated NP‐STEP 46 degradation via K6 ‐linked ubiquitination sustains ERK activity in lung cancer

(2022) Qian Wang et al.   Molecular Oncology

PCAT-1 facilitates breast cancer progression via binding to RACK1 and enhancing oxygen-independent stability of hypoxia-inducible factor-1α

(2021) Jianlong Wang et al.   Molecular Therapy-Nucleic Acids

MiR-195 inhibits the ubiquitination and degradation of YY1 by Smurf2, and induces EMT and cell permeability of retinal pigment epithelial cells

(2021) Shu-Hua Fu et al.   Cell Death & Disease

RACK1 Prevents the Premature Differentiation of Epidermal Progenitor Cells by Inhibiting IRF6 Expression

(2021) Ji Ling et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Interplay between protein acetylation and ubiquitination controls MCL1 protein stability

(2021) Kouhei Shimizu et al.   Cell Reports

Dual functions of Rack1 in regulating Hedgehog pathway

(2020) Yan Li et al.   CELL DEATH AND DIFFERENTIATION

The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt–PCAF pathway in promotion of esophageal squamous cell carcinoma growth

(2020) Yue Wu et al.   NUCLEIC ACIDS RESEARCH

Ubiquitination-mediated degradation of SIRT1 by SMURF2 suppresses CRC cell proliferation and tumorigenesis

(2020) Le Yu et al.   ONCOGENE

Acetylation Stabilizes Phosphoglycerate Dehydrogenase by Disrupting the Interaction of E3 Ligase RNF5 to Promote Breast Tumorigenesis

(2020) Chao Wang et al.   Cell Reports

Opposite regulation of Wnt/β-catenin and Shh signaling pathways by Rack1 controls mammalian cerebellar development

(2019) Haihong Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversible regulation of SATB1 ubiquitination by USP47 and SMURF2 mediates colon cancer cell proliferation and tumor progression

(2019) Le Yu et al.   CANCER LETTERS

Rack1 mediates Src binding to drug transporter P-glycoprotein and modulates its activity through regulating Caveolin-1 phosphorylation in breast cancer cells

(2019) Yanling Fan et al.   Cell Death & Disease

RACK1 promotes the invasive activities and lymph node metastasis of cervical cancer via galectin-1

(2019) Hao Wu et al.   CANCER LETTERS

O -GlcNAcylation of RACK1 promotes hepatocellular carcinogenesis

(2018) Fangfang Duan et al.   JOURNAL OF HEPATOLOGY

Functions and mechanisms of non-histone protein acetylation

(2018) Takeo Narita et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The ubiquitin–proteasome system and its potential application in hepatocellular carcinoma therapy

(2016) Yan-Jie Chen et al.   CANCER LETTERS

Types of Ubiquitin Ligases

(2016) Francesca Ester Morreale et al.   CELL

Fucose-containing fraction of Ling-Zhi enhances lipid rafts-dependent ubiquitination of TGFβ receptor degradation and attenuates breast cancer tumorigenesis

(2016) Shu-Ming Tsao et al.   Scientific Reports

Silencing the receptor of activated C-kinase 1 (RACK1) suppresses tumorigenicity in epithelial ovarian cancer in vitro and in vivo

(2014) YANG LIN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells

(2013) Parnetta Sutton et al.   Molecular Cancer

Overexpressions of RACK1 and CD147 Associated with Poor Prognosis in Stage T1 Pulmonary Adenocarcinoma

(2012) Xinwen Zhong et al.   ANNALS OF SURGICAL ONCOLOGY

A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20

(2012) Michael Blank et al.   NATURE MEDICINE

Diversity of Polyubiquitin Chains

(2009) Anirban Adhikari et al.   DEVELOPMENTAL CELL