The BCL2 inhibitor venetoclax mediates anticancer effects through dendritic cell activation

First-Line Venetoclax Combinations in Chronic Lymphocytic Leukemia

(2023) Barbara Eichhorst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immunogenic cell death (ICD) enhancers—Drugs that enhance the perception of ICD by dendritic cells

(2023) Peng Liu et al.   IMMUNOLOGICAL REVIEWS

Mechanisms of BCL-2 family proteins in mitochondrial apoptosis

(2023) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BCL2 Inhibition Reveals a Dendritic Cell–Specific Immune Checkpoint That Controls Tumor Immunosurveillance

(2023) Liwei Zhao et al.   Cancer Discovery

Anticancer effects of ikarugamycin and astemizole identified in a screen for stimulators of cellular immune responses

(2023) Shuai Zhang et al.   Journal for ImmunoTherapy of Cancer

Immunogenic cell stress and death

(2022) Guido Kroemer et al.   NATURE IMMUNOLOGY

Drugging the efferocytosis process: concepts and opportunities

(2022) Parul Mehrotra et al.   NATURE REVIEWS DRUG DISCOVERY

Dendritic Cells Revisited

(2021) Mar Cabeza-Cabrerizo et al.   Annual Review of Immunology

Noncanonical Cell Fate Regulation by Bcl-2 Proteins

(2020) Stephen Jun Fei Chong et al.   TRENDS IN CELL BIOLOGY

Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors

(2020) Lorenzo Galluzzi et al.   Nature Reviews Clinical Oncology

Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia

(2020) Courtney D. DiNardo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Flotetuzumab as Salvage Immunotherapy for Refractory Acute Myeloid Leukemia

(2020) Geoffrey L Uy et al.   BLOOD

A TLR3 ligand reestablishes chemotherapeutic responses in the context of FPR1 deficiency

(2020) Julie Le Naour et al.   Cancer Discovery

Venetoclax increases intra-tumoral effector T cells and anti-tumor efficacy in combination with immune checkpoint blockade

(2020) Frederick J Kohlhapp et al.   Cancer Discovery

Immunomodulation by targeted anticancer agents

(2020) Giulia Petroni et al.   CANCER CELL

Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

(2019) Rumani Singh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients

(2019) Iva Truxova et al.   HAEMATOLOGICA

Apoptosis and Clearance of Apoptotic Cells

(2018) Shigekazu Nagata   Annual Review of Immunology

Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study

(2018) Courtney D DiNardo et al.   LANCET ONCOLOGY

Linking cellular stress responses to systemic homeostasis

(2018) Lorenzo Galluzzi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Efficacy, Safety, and Biomarkers of Response to Azacitidine and Nivolumab in Relapsed/Refractory Acute Myeloid Leukemia: A Non-randomized, Open-label, Phase 2 Study

(2018) Naval Daver et al.   Cancer Discovery

Venetoclax: First Global Approval

(2016) Emma D. Deeks   DRUGS

Venetoclax in relapsed or refractory chronic lymphocytic leukaemia with 17p deletion: a multicentre, open-label, phase 2 study

(2016) Stephan Stilgenbauer et al.   LANCET ONCOLOGY

Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia

(2016) Andrew W. Roberts et al.   NEW ENGLAND JOURNAL OF MEDICINE

Individualized vaccination of AML patients in remission is associated with induction of antileukemia immunity and prolonged remissions

(2016) J. Rosenblatt et al.   Science Translational Medicine

Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents

(2015) Lorenzo Galluzzi et al.   CANCER CELL

Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells

(2013) Yuting Ma et al.   IMMUNITY

Generation of Inducible Immortalized Dendritic Cells with Proper Immune Function In Vitro and In Vivo

(2013) Cornelia Richter et al.   PLoS One

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

Decoding Cell Death Signals in Inflammation and Immunity

(2010) Laurence Zitvogel et al.   CELL

Calreticulin exposure on malignant blasts predicts a cellular anticancer immune response in patients with acute myeloid leukemia

(2010) M Wemeau et al.   Cell Death & Disease

The anticancer immune response: indispensable for therapeutic success?

(2008) Laurence Zitvogel et al.   JOURNAL OF CLINICAL INVESTIGATION

Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset

(2008) M. L. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE