In-cell depolymerization of polysaccharide antigens. Exploring the processing pathways of glycans and why some glycoconjugate vaccines are less effective than expected: A review

Impact and Control of Sugar Size in Glycoconjugate Vaccines

(2022) Giuseppe Stefanetti et al.   MOLECULES

Structure and Immunogenicity of the Bordetella pertussis LOS-Derived Oligosaccharides in the Endosomal-Like Pre-Processing Mice Model

(2021) Sabina Koj et al.   Vaccines

Glycopeptide epitope facilitates HIV-1 envelope specific humoral immune responses by eliciting T cell help

(2020) Lina Sun et al.   Nature Communications

H2S and reactive sulfur signaling at the host bacterial pathogen interface

(2020) Brenna J.C. Walsh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-acetylation of typhoid capsular polysaccharide confers polysaccharide rigidity and immunodominance by masking additional epitopes

(2019) Krisztina Hitri et al.   VACCINE

Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine

(2018) Rafael Radi   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polysaccharide structure dictates mechanism of adaptive immune response to glycoconjugate vaccines

(2018) Ximei Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T Cell–Mediated Humoral Immune Responses to Type 3 Capsular Polysaccharide ofStreptococcus pneumoniae

(2017) Dustin R. Middleton et al.   JOURNAL OF IMMUNOLOGY

O-Acetylation is essential for functional antibody generation against Staphylococcus aureus capsular polysaccharide

(2017) Ingrid L. Scully et al.   Human Vaccines & Immunotherapeutics

Neutrophils to the ROScue: Mechanisms of NADPH Oxidase Activation and Bacterial Resistance

(2017) Giang T. Nguyen et al.   Frontiers in Cellular and Infection Microbiology

Sulfide Homeostasis and Nitroxyl Intersect via Formation of Reactive Sulfur Species in Staphylococcus aureus

(2017) Hui Peng et al.   mSphere

Sialic Acids in the Brain: Gangliosides and Polysialic Acid in Nervous System Development, Stability, Disease, and Regeneration

(2014) Ronald L. Schnaar et al.   PHYSIOLOGICAL REVIEWS

Carbohydrates and T cells: A sweet twosome

(2013) Fikri Y. Avci et al.   SEMINARS IN IMMUNOLOGY

Single priming dose of meningococcal group C conjugate vaccine (NeisVac-C®) in infants

(2013) Eva-Maria Poellabauer et al.   VACCINE

Synthetic Vaccines from Tumor-Associated Glycopeptide Antigens

(2011) Ulrika Westerlind et al.   CHIMIA

Meningococcal glycoconjugate vaccines

(2011) Roberto Gasparini et al.   Human vaccines & immunotherapeutics

A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design

(2011) Fikri Y Avci et al.   NATURE MEDICINE

Oxidative depolymerization of polysaccharides by reactive oxygen/nitrogen species

(2010) J. Duan et al.   GLYCOBIOLOGY

Carbohydrate Oxidation Acidifies Endosomes, Regulating Antigen Processing and TLR9 Signaling

(2010) C. J. Lewis et al.   JOURNAL OF IMMUNOLOGY

How Bacterial Carbohydrates Influence the Adaptive Immune System

(2009) Fikri Y. Avci et al.   Annual Review of Immunology

Beneficial effects of Bacteroides fragilis polysaccharides on the immune system

(2009) Erin et al.   Frontiers in Bioscience-Landmark

Vaccines Containing de- N -Acetyl Sialic Acid Elicit Antibodies Protective against Neisseria meningitidis Groups B and C

(2009) Gregory R. Moe et al.   JOURNAL OF IMMUNOLOGY

Antigen processing of glycoconjugate vaccines; the polysaccharide portion of the pneumococcal CRM197 conjugate vaccine co-localizes with MHC II on the antigen processing cell surface

(2009) Zengzu Lai et al.   VACCINE

Characteristics of carbohydrate antigen binding to the presentation protein HLA-DR

(2008) Brian A Cobb et al.   GLYCOBIOLOGY

Type I Streptococcus pneumoniae carbohydrate utilizes a nitric oxide and MHC II-dependent pathway for antigen presentation

(2008) Christopher D. Velez et al.   IMMUNOLOGY

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE

Microbial carbohydrate depolymerization by antigen-presenting cells: Deamination prior to presentation by the MHCII pathway

(2008) Jinyou Duan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

(2008) Caroline L. Trotter et al.   VACCINE