Small molecule inhibition of TFF3 overcomes tamoxifen resistance and enhances taxane efficacy in ER+ mammary carcinoma
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Title
Small molecule inhibition of TFF3 overcomes tamoxifen resistance and enhances taxane efficacy in ER+ mammary carcinoma
Authors
Keywords
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Journal
CANCER LETTERS
Volume 579, Issue -, Pages 216443
Publisher
Elsevier BV
Online
2023-10-17
DOI
10.1016/j.canlet.2023.216443
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Note: Only part of the references are listed.- A Pro-Regenerative Environment Triggers Premalignant to Malignant Transformation of Senescent Hepatocytes
- (2023) Anna Wuestefeld et al. CANCER RESEARCH
- BC-DETECT: combined detection of serum HE4 and TFF3 improves breast cancer diagnostic efficacy
- (2022) Mohamed A. Abdelrazek et al. Breast Cancer
- Correlation between CA12 and TFF3 and their prediction value of neoadjuvant chemotherapy response in breast cancer
- (2022) Mengjia Shen et al. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
- Trefoil factor 3 promotes pancreatic carcinoma progression via WNT pathway activation mediated by enhanced WNT ligand expression
- (2022) Feifei Cheng et al. Cell Death & Disease
- BCL-2 protein family: attractive targets for cancer therapy
- (2022) Deeksha Kaloni et al. APOPTOSIS
- Mitochondria: The metabolic switch of cellular oncogenic transformation
- (2021) Yan Qin Tan et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway
- (2021) Yunchao Xin et al. Evidence-based Complementary and Alternative Medicine
- Chemical Synthesis of TFF3 Reveals Novel Mechanistic Insights and a Gut-Stable Metabolite
- (2021) Nayara Braga Emidio et al. JOURNAL OF MEDICINAL CHEMISTRY
- Tamoxifen resistance alters sensitivity to 5-fluorouracil in a subset of estrogen receptor-positive breast cancer
- (2021) Takayuki Watanabe et al. PLoS One
- DEHP mediates drug resistance by directly targeting AhR in human breast cancer
- (2021) Tsung-Hua Hsieh et al. BIOMEDICINE & PHARMACOTHERAPY
- Endocrine resistance and epigenetic reprogramming in estrogen receptor positive breast cancer
- (2021) Foteinos-Ioannis Dimitrakopoulos et al. CANCER LETTERS
- Analysis of the Estrogen Receptor-Associated LncRNA Landscape Identifies a Role for ERLC1 in Breast Cancer Progression
- (2021) Hui Yuan et al. CANCER RESEARCH
- Overcoming Endocrine Resistance in Breast Cancer
- (2020) Ariella B. Hanker et al. CANCER CELL
- Breast Cancer, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology
- (2020) William J. Gradishar et al. Journal of the National Comprehensive Cancer Network
- LINC00160 mediated paclitaxel‐And doxorubicin‐resistance in breast cancer cells by regulating TFF3 via transcription factor C/EBPβ
- (2020) Huaiguo Wu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- 5th ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 5)†
- (2020) F. Cardoso et al. ANNALS OF ONCOLOGY
- Cancer stem cells: Culprits in endocrine resistance and racial disparities in breast cancer outcomes
- (2020) Nicole Mavingire et al. CANCER LETTERS
- The activity of transient receptor potential channel C-6 modulates the differentiation of fat cells
- (2019) Yan Qin Tan et al. FASEB JOURNAL
- Trefoil factors peptide-3 is associated with residual invasive breast carcinoma following neoadjuvant chemotherapy
- (2019) Suhail Al-Salam et al. BMC CANCER
- The Central Contributions of Breast Cancer Stem Cells in Developing Resistance to Endocrine Therapy in Estrogen Receptor (ER)-Positive Breast Cancer
- (2019) David Rodriguez et al. Cancers
- Dynamic interactions between the extracellular matrix and estrogen activity in progression of ER+ breast cancer
- (2019) Fatou Jallow et al. ONCOGENE
- A Novel Paclitaxel Conjugate with Higher Efficiency and Lower Toxicity: A New Drug Candidate for Cancer Treatment
- (2019) Falah et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths
- (2019) Nicole Maloney Belle et al. Nature Communications
- A novel small-molecule inhibitor of trefoil factor 3 (TFF3) potentiates MEK1/2 inhibition in lung adenocarcinoma
- (2019) Mengyi Zhang et al. Oncogenesis
- Inhibition of TFF3 Enhances Sensitivity—and Overcomes Acquired Resistance—to Doxorubicin in Estrogen Receptor-Positive Mammary Carcinoma
- (2019) Han Poh et al. Cancers
- Pharmacological Inhibition of TFF3 Enhances Sensitivity of CMS4 Colorectal Carcinoma to 5-Fluorouracil through Inhibition of p44/42 MAPK
- (2019) Ru-Mei Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sabutoclax, pan-active BCL-2 protein family antagonist, overcomes drug resistance and eliminates cancer stem cells in breast cancer
- (2018) Yunhui Hu et al. CANCER LETTERS
- Tamoxifen-resistant breast cancer cells are resistant to DNA-damaging chemotherapy because of upregulated BARD1 and BRCA1
- (2018) Yinghua Zhu et al. Nature Communications
- Expression of two non-mutated genetic elements is sufficient to stimulate oncogenic transformation of human mammary epithelial cells
- (2018) Vijay Pandey et al. Cell Death & Disease
- LEM4 confers tamoxifen resistance to breast cancer cells by activating cyclin D-CDK4/6-Rb and ERα pathway
- (2018) Ang Gao et al. Nature Communications
- Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer
- (2017) Pasquale Sansone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Release of HER2 repression of trefoil factor 3 (TFF3) expression mediates trastuzumab resistance in HER2+/ER+ mammary carcinoma
- (2017) Qing-Yun Chong et al. Oncotarget
- Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent
- (2017) Ming-Liang You et al. Oncotarget
- Hypomethylation associated enhanced transcription of trefoil factor-3 mediates tamoxifen-stimulated oncogenicity of ER+ endometrial carcinoma cells
- (2017) Vijay Pandey et al. Oncotarget
- Microtubule destabilising agents: far more than just antimitotic anticancer drugs
- (2016) Darcy Bates et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Breast cancer stem cell: the roles and therapeutic implications
- (2016) Fang Yang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Overcoming Resistance to Endocrine Therapy in Breast Cancer: New Approaches to a Nagging Problem
- (2016) Yunus A. Luqmani et al. MEDICAL PRINCIPLES AND PRACTICE
- Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia
- (2016) Andrew W. Roberts et al. NEW ENGLAND JOURNAL OF MEDICINE
- Enhanced efficacy of chemotherapy for breast cancer stem cells by simultaneous suppression of multidrug resistance and antiapoptotic cellular defense
- (2015) Ming Sun et al. Acta Biomaterialia
- Gene expression alterations associated with outcome in aromatase inhibitor-treated ER+ early-stage breast cancer patients
- (2015) Karina G. Thomsen et al. BREAST CANCER RESEARCH AND TREATMENT
- TFF3 is a valuable predictive biomarker of endocrine response in metastatic breast cancer
- (2015) F. E. B. May et al. ENDOCRINE-RELATED CANCER
- High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
- (2015) Hui Gao et al. NATURE MEDICINE
- ESR1 mutations—a mechanism for acquired endocrine resistance in breast cancer
- (2015) Rinath Jeselsohn et al. Nature Reviews Clinical Oncology
- Targeting BCL-2 to enhance vulnerability to therapy in estrogen receptor-positive breast cancer
- (2015) D Merino et al. ONCOGENE
- Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer
- (2015) Jun Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Functionally Significant Cross-talk between Androgen Receptor and ErbB2 Pathways in Estrogen Receptor Negative Breast Cancer
- (2015) Ali Naderi et al. NEOPLASIA
- Trefoil Factor 3 Is Oncogenic and Mediates Anti-Estrogen Resistance in Human Mammary Carcinoma
- (2015) Nagarajan Kannan et al. NEOPLASIA
- Lycopene Enhances Docetaxel's Effect in Castration-Resistant Prostate Cancer Associated with Insulin-like Growth Factor I Receptor Levels
- (2015) Yaxiong Tang et al. NEOPLASIA
- Intestinal trefoil factor activates the PI3K/Akt signaling pathway to protect gastric mucosal epithelium from damage
- (2014) ZHAORUI SUN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Artemin, a Member of the Glial Cell Line-derived Neurotrophic Factor Family of Ligands, Is HER2-regulated and Mediates Acquired Trastuzumab Resistance by Promoting Cancer Stem Cell-like Behavior in Mammary Carcinoma Cells
- (2014) Keshuo Ding et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The protective effect of trefoil factor 3 on the intestinal tight junction barrier is mediated by toll-like receptor 2 via a PI3K/Akt dependent mechanism
- (2013) Nan Lin et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Targeting BCL-2 with the BH3 Mimetic ABT-199 in Estrogen Receptor-Positive Breast Cancer
- (2013) François Vaillant et al. CANCER CELL
- Dysregulation of the epigenome in triple-negative breast cancers: Basal-like and claudin-low breast cancers express aberrant DNA hypermethylation
- (2013) J. Devon Roll et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Prognostic value of Bcl-2 in two independent populations of estrogen receptor positive breast cancer patients treated with adjuvant endocrine therapy
- (2012) Mathilde S. Larsen et al. ACTA ONCOLOGICA
- TFF3 Is a Normal Breast Epithelial Protein and Is Associated with Differentiated Phenotype in Early Breast Cancer but Predisposes to Invasion and Metastasis in Advanced Disease
- (2012) Ahmed R.H. Ahmed et al. AMERICAN JOURNAL OF PATHOLOGY
- Upregulation of Trefoil Factor 3 (TFF3) After Rectal Cancer Chemoradiotherapy Is an Adverse Prognostic Factor and a Potential Therapeutic Target
- (2012) Enrique Casado et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Estrogen receptor-related genes as an important panel of predictors for breast cancer response to neoadjuvant chemotherapy
- (2011) Yizuo Chen et al. CANCER LETTERS
- Tests for Serum Levels of Trefoil Factor Family Proteins Can Improve Gastric Cancer Screening
- (2011) Susumu Aikou et al. GASTROENTEROLOGY
- Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy
- (2011) Eric A Collisson et al. NATURE MEDICINE
- Mitosis is not a key target of microtubule agents in patient tumors
- (2011) Edina Komlodi-Pasztor et al. Nature Reviews Clinical Oncology
- Implications of Anthracycline-Resistant and Taxane-Resistant Metastatic Breast Cancer and New Therapeutic Options
- (2010) Edgardo Rivera Breast Journal
- BCL2 in breast cancer: a favourable prognostic marker across molecular subtypes and independent of adjuvant therapy received
- (2010) S-J Dawson et al. BRITISH JOURNAL OF CANCER
- Treatment Options for Breast Cancer Resistant to Anthracycline and Taxane
- (2009) Alvaro Moreno-Aspitia et al. MAYO CLINIC PROCEEDINGS
- Trefoil factor 3: a novel serum marker identified by gene expression profiling in high-grade endometrial carcinomas
- (2008) E Bignotti et al. BRITISH JOURNAL OF CANCER
- Bcl-2 inhibitors: small molecules with a big impact on cancer therapy
- (2008) M Vogler et al. CELL DEATH AND DIFFERENTIATION
- Cytochrome c: functions beyond respiration
- (2008) Yong-Ling P. Ow et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cellular Mechanisms of Resistance to Anthracyclines and Taxanes in Cancer: Intrinsic and Acquired
- (2008) A. Jo Chien et al. SEMINARS IN ONCOLOGY
- Are trefoil factors oncogenic?
- (2007) Jo K. Perry et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
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