RAD54B inhibits vascular endothelial senescence via suppression of CHK1/p53/p21 pathway

The p53 network: cellular and systemic DNA damage responses in cancer and aging

(2022) Pavana Lakshmi Vaddavalli et al.   TRENDS IN GENETICS

Mechanisms and consequences of endothelial cell senescence

(2022) Samuel I. Bloom et al.   Nature Reviews Cardiology

The central role of DNA damage in the ageing process

(2021) Björn Schumacher et al.   NATURE

KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis

(2021) Dechao Bu et al.   NUCLEIC ACIDS RESEARCH

HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity

(2021) Wenwei Luo et al.   Cell Death & Disease

A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling

(2021) Daipayan Banerjee et al.   Nature Communications

LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity

(2021) Pengyi Yan et al.   Cell Reports

Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan

(2020) Laurent Grosse et al.   Cell Metabolism

RAD51: Beyond the break

(2020) Isabel E. Wassing et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Fight to the bitter end: DNA repair and aging

(2020) Yu Chen et al.   AGEING RESEARCH REVIEWS

PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis

(2019) Caiyun G. Li et al.   Cell Reports

Transcriptome signature of cellular senescence

(2019) Gabriel Casella et al.   NUCLEIC ACIDS RESEARCH

Knockdown of RAD54B expression reduces cell proliferation and induces apoptosis in lung cancer cells

(2019) Chuan Xu et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

RAD54B potentiates tumor growth and predicts poor prognosis of patients with luminal A breast cancer

(2019) Zeyu Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Heme oxygenase-1 ameliorates oxidative stress-induced endothelial senescence via regulating endothelial nitric oxide synthase activation and coupling

(2018) Wenwei Luo et al.   Aging-US

The enigmatic oncogene and tumor suppressor-like properties of RAD54B: Insights into genome instability and cancer

(2017) Erin N. McAndrew et al.   GENES CHROMOSOMES & CANCER

Sliding sleeves of XRCC4–XLF bridge DNA and connect fragments of broken DNA

(2016) Ineke Brouwer et al.   NATURE

The role of DNA damage and repair in atherosclerosis: A review

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Ageing, metabolism and cardiovascular disease

(2015) Sarah Costantino et al.   JOURNAL OF PHYSIOLOGY-LONDON

Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes

(2015) Mikhail Shaposhnikov et al.   Scientific Reports

Rad54B serves as a scaffold in the DNA damage response that limits checkpoint strength

(2014) Takaaki Yasuhara et al.   Nature Communications

Genome Instability and Aging

(2013) Jan Vijg et al.   Annual Review of Physiology

Activation of the BRCA1/Chk1/p53/p21Cip1/Waf1 pathway by nitric oxide and cell cycle arrest in human neuroblastoma NB69 cells

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XRCC4's interaction with XLF is required for coding (but not signal) end joining

(2012) S. Roy et al.   NUCLEIC ACIDS RESEARCH

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence

(2012) Graeme Hewitt et al.   Nature Communications

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Functions of the Snf2/Swi2 family Rad54 motor protein in homologous recombination

(2011) Shannon J. Ceballos et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Gambogic acid triggers DNA damage signaling that induces p53/p21Waf1/CIP1 activation through the ATR-Chk1 pathway

(2010) Jing-Jing Rong et al.   CANCER LETTERS

Homologous recombination in DNA repair and DNA damage tolerance

(2008) Xuan Li et al.   CELL RESEARCH

Modification of the ATM/ATR directed DNA damage response state with aging and long after hepatocyte senescence induction in vivo

(2008) Suchismita Panda et al.   MECHANISMS OF AGEING AND DEVELOPMENT