Total neoadjuvant therapy in oesophageal and gastro-oesophageal junctional adenocarcinoma
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Title
Total neoadjuvant therapy in oesophageal and gastro-oesophageal junctional adenocarcinoma
Authors
Keywords
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Journal
BRITISH JOURNAL OF CANCER
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-10-28
DOI
10.1038/s41416-023-02458-w
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Note: Only part of the references are listed.- Long-Term Postsurgical Outcomes of Neoadjuvant Chemoradiation (CROSS) Versus Chemotherapy (FLOT) for Multimodal Treatment of Adenocarcinoma of the Esophagus and the Esophagogastric Junction
- (2023) Florian Gebauer et al. ANNALS OF SURGICAL ONCOLOGY
- KEYNOTE-859 study of pembrolizumab plus chemotherapy for advanced HER2-negative gastric or gastroesophageal junction (G/GEJ) cancer: Outcomes in the protocol-specified PD-L1–selected populations.
- (2023) Sun Young Rha et al. JOURNAL OF CLINICAL ONCOLOGY
- Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiation in patients with locally advanced rectal cancer: 7-year results of PRODIGE 23 phase III trial, a UNICANCER GI trial.
- (2023) Thierry Conroy et al. JOURNAL OF CLINICAL ONCOLOGY
- Facing adenocarcinoma of distal esophagus and esophagogastric junction: a CROSS versus FLOT propensity score-matched analysis of oncological outcomes in a high-volume institution
- (2023) Pietro Maria Lombardi et al. Updates in Surgery
- ATTRACTION-5: A phase 3 study of nivolumab plus chemotherapy as postoperative adjuvant treatment for pathological stage III (pStage III) gastric or gastroesophageal junction (G/GEJ) cancer.
- (2023) Masanori Terashima et al. JOURNAL OF CLINICAL ONCOLOGY
- Induction FOLFOX prior to CROSS chemoradiotherapy and surgery in patients with locally-advanced esophageal and gastroesophageal junction cancer: A phase II study.
- (2022) Richard Francis Dunne et al. JOURNAL OF CLINICAL ONCOLOGY
- Association of circulating tumor DNA dynamics with clinical outcomes in the adjuvant setting for patients with colorectal cancer from an observational GALAXY study in CIRCULATE-Japan.
- (2022) Masahito Kotaka et al. JOURNAL OF CLINICAL ONCOLOGY
- Could Total Neoadjuvant Therapy Followed by Surgical Resection Be the New Standard of Care in Pancreatic Cancer? A Systematic Review and Meta-Analysis
- (2022) Ottavia De Simoni et al. Journal of Clinical Medicine
- Completion of FLOT Therapy, Regardless of Tumor Regression, Significantly Improves Overall Survival in Patients with Esophageal Adenocarcinoma
- (2022) Björn-Ole Stüben et al. Cancers
- Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy
- (2022) Julio Garcia-Aguilar et al. JOURNAL OF CLINICAL ONCOLOGY
- Survival outcomes of neoadjuvant and adjuvant chemoradiotherapy for locally advanced adenocarcinoma of the oesophagogastric junction: a retrospective cohort study using the SEER database
- (2022) Fan Zhang et al. Journal of Gastrointestinal Oncology
- CROSS Versus FLOT Regimens in Esophageal and Esophagogastric Junction Adenocarcinoma: A Propensity-matched Comparison
- (2022) Noel E. Donlon et al. ANNALS OF SURGERY
- Recurrent Disease after Esophageal Cancer Surgery: A Substudy of The Dutch Nationwide Ivory Study
- (2022) Marianne C. Kalff et al. ANNALS OF SURGERY
- An International Cohort Study of Prognosis Associated with Pathologically Complete Response Following Neoadjuvant Chemotherapy versus Chemoradiotherapy of Surgical Treated Esophageal Adenocarcinoma
- (2022) Jonathan Cools-Lartigue et al. ANNALS OF SURGERY
- Total neoadjuvant therapy for locally advanced gastric cancer and esophagogastric junction adenocarcinoma: study protocol for a prospective, multicenter, single-arm, phase II clinical trial
- (2022) Jinming Shi et al. BMC GASTROENTEROLOGY
- Surgical and pathological outcome, and pathological regression, in patients receiving perioperative atezolizumab in combination with FLOT chemotherapy versus FLOT alone for resectable esophagogastric adenocarcinoma: Interim results from DANTE, a randomized, multicenter, phase IIb trial of the FLOT-AIO German Gastric Cancer Group and Swiss SAKK.
- (2022) Salah-Eddin Al-Batran et al. JOURNAL OF CLINICAL ONCOLOGY
- Neoadjuvant Nivolumab Plus Ipilimumab and Adjuvant Nivolumab in Localized Deficient Mismatch Repair/Microsatellite Instability-High Gastric or Esophagogastric Junction Adenocarcinoma: The GERCOR NEONIPIGA Phase II Study
- (2022) Thierry André et al. JOURNAL OF CLINICAL ONCOLOGY
- Rectal Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology
- (2022) Al B. Benson et al. Journal of the National Comprehensive Cancer Network
- Association of total neoadjuvant therapy with favorable clinical outcomes in patients with locally advanced esophageal and gastroesophageal junction adenocarcinomas (LA-GEJ CA).
- (2021) Lauren Jurkowski et al. JOURNAL OF CLINICAL ONCOLOGY
- The AUGIS Survival Predictor
- (2021) Saqib A. Rahman et al. ANNALS OF SURGERY
- Induction Chemotherapy Plus Neoadjuvant Chemoradiation for Esophageal and Gastroesophageal Junction Adenocarcinoma
- (2021) Felix Ho et al. ANNALS OF SURGICAL ONCOLOGY
- Total neoadjuvant FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy and adjuvant gemcitabine for resectable and borderline resectable pancreatic cancer (PREOPANC-2 trial): study protocol for a nationwide multicenter randomized controlled trial
- (2021) Q. P. Janssen et al. BMC CANCER
- Clinical Impact of Presurgery Circulating Tumor DNA after Total Neoadjuvant Treatment in Locally Advanced Rectal Cancer: A Biomarker Study from the GEMCAD 1402 Trial
- (2021) Joana Vidal et al. CLINICAL CANCER RESEARCH
- Prognostic relevance of lymph node regression on survival in esophageal cancer: a systematic review and meta-analysis
- (2021) Eliza Hagens et al. DISEASES OF THE ESOPHAGUS
- Ten-Year Outcome of Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer: The Randomized Controlled CROSS Trial
- (2021) Ben M. Eyck et al. JOURNAL OF CLINICAL ONCOLOGY
- Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial
- (2021) Thierry Conroy et al. LANCET ONCOLOGY
- Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer
- (2021) Ronan J. Kelly et al. NEW ENGLAND JOURNAL OF MEDICINE
- Induction FOLFOX and PET-Directed Chemoradiation For Locally Advanced Esophageal Adenocarcinoma
- (2021) Rebecca A. Carr et al. ANNALS OF SURGERY
- Results and molecular correlates from a pilot study of neoadjuvant induction FOLFIRINOX followed by chemoradiation and surgery for gastroesophageal adenocarcinomas
- (2021) Jennifer Y. Wo et al. CLINICAL CANCER RESEARCH
- Clinical utility and applicability of circulating tumor DNA testing in esophageal cancer: a systematic review and meta-analysis
- (2021) Swathikan Chidambaram et al. DISEASES OF THE ESOPHAGUS
- PRODIGY: A Phase III Study of Neoadjuvant Docetaxel, Oxaliplatin, and S-1 Plus Surgery and Adjuvant S-1 Versus Surgery and Adjuvant S-1 for Resectable Advanced Gastric Cancer
- (2021) Yoon-Koo Kang et al. JOURNAL OF CLINICAL ONCOLOGY
- Neo-AEGIS (Neoadjuvant trial in Adenocarcinoma of the Esophagus and Esophago-Gastric Junction International Study): Preliminary results of phase III RCT of CROSS versus perioperative chemotherapy (Modified MAGIC or FLOT protocol). (NCT01726452).
- (2021) John V. Reynolds et al. JOURNAL OF CLINICAL ONCOLOGY
- Adjuvant nivolumab (NIVO) in resected esophageal or gastroesophageal junction cancer (EC/GEJC) following neoadjuvant chemoradiotherapy (CRT): Expanded efficacy and safety analyses from CheckMate 577.
- (2021) Ronan Joseph Kelly et al. JOURNAL OF CLINICAL ONCOLOGY
- Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 study
- (2021) Jong-Mu Sun et al. LANCET
- First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial
- (2021) Yelena Y Janjigian et al. LANCET
- Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer
- (2021) Emmanouil Fokas et al. JAMA Oncology
- Operative Results and Perioperative Morbidity After Intensified Neoadjuvant Chemotherapy with FLOT for Gastroesophageal Adenocarcinoma Impact of Intensified Neoadjuvant Treatment
- (2020) Petra Ganschow et al. JOURNAL OF GASTROINTESTINAL SURGERY
- Lymph Node and Bone Marrow Micrometastases Define the Prognosis of Patients with pN0 Esophageal Cancer
- (2020) Karl-F. Karstens et al. Cancers
- Serial circulating tumour DNA analysis for locally advanced rectal cancer treated with preoperative therapy: prediction of pathological response and postoperative recurrence
- (2020) Satoshi Murahashi et al. BRITISH JOURNAL OF CANCER
- MSI as a predictive factor for treatment outcome of gastroesophageal adenocarcinoma
- (2020) M.J.M. van Velzen et al. CANCER TREATMENT REVIEWS
- ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper
- (2020) Arvind Dasari et al. Nature Reviews Clinical Oncology
- Compliance and tolerability of short-course radiotherapy followed by preoperative chemotherapy and surgery for high-risk rectal cancer – Results of the international randomized RAPIDO-trial
- (2020) Maxime J.M. van der Valk et al. RADIOTHERAPY AND ONCOLOGY
- Total Neoadjuvant Therapy for Operable Pancreatic Cancer
- (2020) Rebecca Y. Kim et al. ANNALS OF SURGICAL ONCOLOGY
- RACE-trial: neoadjuvant radiochemotherapy versus chemotherapy for patients with locally advanced, potentially resectable adenocarcinoma of the gastroesophageal junction - a randomized phase III joint study of the AIO, ARO and DGAV
- (2020) Sylvie Lorenzen et al. BMC CANCER
- Prognostic significance of postsurgery circulating tumor DNA in nonmetastatic colorectal cancer: Individual patient pooled analysis of three cohort studies
- (2020) Jeanne Tie et al. INTERNATIONAL JOURNAL OF CANCER
- Spatial profiling of gastric cancer patient-matched primary and locoregional metastases reveals principles of tumour dissemination
- (2020) Raghav Sundar et al. GUT
- Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial
- (2020) Renu R Bahadoer et al. LANCET ONCOLOGY
- Total Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer
- (2020) Anup Kasi et al. JAMA Network Open
- Detection of Circulating Tumor DNA in Plasma: A Potential Biomarker for Esophageal Adenocarcinoma
- (2019) Matthew Egyud et al. ANNALS OF THORACIC SURGERY
- Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial
- (2019) Salah-Eddin Al-Batran et al. LANCET
- Long-course preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for clinical T4 and fixed clinical T3 rectal cancer: long-term results of the randomized Polish II study
- (2019) B Ciseł et al. ANNALS OF ONCOLOGY
- Total Neoadjuvant Therapy in Rectal Cancer
- (2019) Fausto Petrelli et al. ANNALS OF SURGERY
- Study protocol of a randomized phase III trial of comparing preoperative chemoradiation with preoperative chemotherapy in patients with locally advanced gastric cancer or esophagogastric junction adenocarcinoma: PREACT
- (2019) Xiaowen Liu et al. BMC CANCER
- Randomized Phase II Trial of Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: CAO/ARO/AIO-12
- (2019) Emmanouil Fokas et al. JOURNAL OF CLINICAL ONCOLOGY
- Adjuvant chemotherapy is associated with improved survival in patients with nodal metastases after neoadjuvant therapy and esophagectomy
- (2019) Justin Drake et al. Journal of Thoracic Disease
- Circulating tumor DNA analysis for detection of minimal residual disease after chemoradiotherapy for localized esophageal cancer
- (2019) Tej D. Azad et al. GASTROENTEROLOGY
- Assessment of Response to Neoadjuvant Chemoradiotherapy by 18F-FDG PET/CT in Patients With Locally Advanced Esophagogastric Junction Adenocarcinoma
- (2019) Nuria Sánchez-Izquierdo et al. CLINICAL NUCLEAR MEDICINE
- 18FDG-PET-CT identifies histopathological non-responders after neoadjuvant chemotherapy in locally advanced gastric and cardia cancer: cohort study
- (2018) Paul M. Schneider et al. BMC CANCER
- Neoadjuvant chemoradiotherapy plus surgery versus active surveillance for oesophageal cancer: a stepped-wedge cluster randomised trial
- (2018) Bo Jan Noordman et al. BMC CANCER
- Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study
- (2018) Jeanne Tie et al. GUT
- Prognostic value of pathological lymph node status and primary tumour regression grading following neoadjuvant chemotherapy - results from the MRC OE02 oesophageal cancer trial
- (2018) Nasser Davarzani et al. HISTOPATHOLOGY
- Adjuvant Chemotherapy for Pathologic Node Positive Esophageal Cancer Patients Following Induction Chemotherapy is Associated with Improved Survival
- (2018) Pamela Samson et al. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
- Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study
- (2018) Maxime J M van der Valk et al. LANCET
- Adjuvant Chemotherapy vs Postoperative Observation Following Preoperative Chemoradiotherapy and Resection in Gastroesophageal Cancer
- (2018) Ali A. Mokdad et al. JAMA Oncology
- Total Neoadjuvant Therapy With FOLFIRINOX Followed by Individualized Chemoradiotherapy for Borderline Resectable Pancreatic Adenocarcinoma
- (2018) Janet E. Murphy et al. JAMA Oncology
- Adoption of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer
- (2018) Andrea Cercek et al. JAMA Oncology
- CRITICS-II: a multicentre randomised phase II trial of neo-adjuvant chemotherapy followed by surgery versus neo-adjuvant chemotherapy and subsequent chemoradiotherapy followed by surgery versus neo-adjuvant chemoradiotherapy followed by surgery in resectable gastric cancer
- (2018) Astrid E. Slagter et al. BMC CANCER
- Lymph node regression and survival following neoadjuvant chemotherapy in oesophageal adenocarcinoma
- (2018) A. R. Davies et al. BRITISH JOURNAL OF SURGERY
- Neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for cancer of the esophagus or gastroesophageal junction: long-term results of a randomized clinical trial
- (2018) G A von Döbeln et al. DISEASES OF THE ESOPHAGUS
- Does timing of esophagectomy following neoadjuvant chemoradiation affect outcomes? A meta-analysis
- (2018) Qin Qin et al. International Journal of Surgery
- Neoadjuvant chemoradiotherapy or chemotherapy for gastroesophageal junction adenocarcinoma: A systematic review and meta-analysis
- (2018) Fausto Petrelli et al. Gastric Cancer
- Preoperative chemotherapy versus chemoradiotherapy in locally advanced adenocarcinomas of the oesophagogastric junction (POET): Long-term results of a controlled randomised trial
- (2017) Michael Stahl et al. EUROPEAN JOURNAL OF CANCER
- Surgical resection after neoadjuvant chemoradiation for oesophageal adenocarcinoma: what is the optimal timing?
- (2017) David N. Ranney et al. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
- Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma
- (2017) Eirini Pectasides et al. Cancer Discovery
- PAN-EX: a pooled analysis of two trials of neoadjuvant chemotherapy followed by chemoradiotherapy in MRI-defined, locally advanced rectal cancer
- (2016) F. Sclafani et al. ANNALS OF ONCOLOGY
- Long-course oxaliplatin-based preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for cT4 or fixed cT3 rectal cancer: results of a randomized phase III study
- (2016) K. Bujko et al. ANNALS OF ONCOLOGY
- ypN0: Does It Matter How You Get There? Nodal Downstaging in Esophageal Cancer
- (2016) Andrea Zanoni et al. ANNALS OF SURGICAL ONCOLOGY
- ESOPEC: prospective randomized controlled multicenter phase III trial comparing perioperative chemotherapy (FLOT protocol) to neoadjuvant chemoradiation (CROSS protocol) in patients with adenocarcinoma of the esophagus (NCT02509286)
- (2016) Jens Hoeppner et al. BMC CANCER
- Effect of Pathologic Tumor Response and Nodal Status on Survival in the Medical Research Council Adjuvant Gastric Infusional Chemotherapy Trial
- (2016) Elizabeth C. Smyth et al. JOURNAL OF CLINICAL ONCOLOGY
- Pathologic Complete Response Is an Independent Predictor of Improved Survival Following Neoadjuvant Chemoradiation for Esophageal Adenocarcinoma
- (2016) Raed M. Alnaji et al. JOURNAL OF GASTROINTESTINAL SURGERY
- Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): results from the phase 2 part of a multicentre, open-label, randomised phase 2/3 trial
- (2016) Salah-Eddin Al-Batran et al. LANCET ONCOLOGY
- Chemoradiation, surgery and adjuvant chemotherapy versus induction chemotherapy followed by chemoradiation and surgery: long-term results of the Spanish GCR-3 phase II randomized trial
- (2015) C. Fernandez-Martos et al. ANNALS OF ONCOLOGY
- NeoFLOT: Multicenter phase II study of perioperative chemotherapy in resectable adenocarcinoma of the gastroesophageal junction or gastric adenocarcinoma-Very good response predominantly in patients with intestinal type tumors
- (2015) Christoph Schulz et al. INTERNATIONAL JOURNAL OF CANCER
- The Interplay of Immunotherapy and Chemotherapy: Harnessing Potential Synergies
- (2015) Leisha A. Emens et al. Cancer Immunology Research
- 18F-FDG PET-CT after Neoadjuvant Chemoradiotherapy in Esophageal Cancer Patients to Optimize Surgical Decision Making
- (2015) Maarten C. J. Anderegg et al. PLoS One
- Outcomes of Preoperative Chemotherapy with Docetaxel, Cisplatin, and 5-Fluorouracil Followed by Esophagectomy in Patients with Resectable Node-Positive Esophageal Cancer
- (2014) Masayuki Watanabe et al. ANNALS OF SURGICAL ONCOLOGY
- Importance of Surveillance and Success of Salvage Strategies After Definitive Chemoradiation in Patients With Esophageal Cancer
- (2014) Kazuki Sudo et al. JOURNAL OF CLINICAL ONCOLOGY
- Adjuvant capecitabine plus oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): 5-year follow-up of an open-label, randomised phase 3 trial
- (2014) Sung Hoon Noh et al. LANCET ONCOLOGY
- Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus
- (2013) Fergus Noble WORLD JOURNAL OF GASTROENTEROLOGY
- Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer
- (2012) P. van Hagen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Fluorodeoxyglucose Positron Emission Tomography for Evaluating Early Response During Neoadjuvant Chemoradiotherapy in Patients With Potentially Curable Esophageal Cancer
- (2011) Mark van Heijl et al. ANNALS OF SURGERY
- Guidelines for the management of oesophageal and gastric cancer
- (2011) W. H. Allum et al. GUT
- Long-Term Results of a Randomized Trial of Surgery With or Without Preoperative Chemotherapy in Esophageal Cancer
- (2009) William H. Allum et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase III Comparison of Preoperative Chemotherapy Compared With Chemoradiotherapy in Patients With Locally Advanced Adenocarcinoma of the Esophagogastric Junction
- (2009) Michael Stahl et al. JOURNAL OF CLINICAL ONCOLOGY
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